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How experienced community neurologists make diagnoses during clinical encounters
We describe 3 core domains of diagnosis: 1) clinical (C), 2) laboratory and electrodiagnostics (L), and 3) neuroimaging (N). Neurologists were uniform in their practices across these domains except within the clinical domain, where the physical examination varied considerably among clinicians. All neurologists coordinated findings from the 3 domains to arrive at a final diagnosis. This practice of coordination varied across common disease categories (e.g., meningitis vs dementia). To codify this variance, we developed a provisional model of diagnostic practice derived from the data consisting of a 3-point coordinate shorth...
Source: Neurology - October 14, 2013 Category: Neurology Authors: Dhand, A., Engstrom, J., Dhaliwal, G. Tags: Cost effectiveness/economic, Decision analysis, All Clinical Neurology, Methods of education CONTEMPORARY ISSUES Source Type: research

National Stroke Registries: What can we learn from them?
Stroke is a major cause of long-term adult disability, death, and health care costs worldwide. This overwhelming burden on global health necessitates ongoing improvements in stroke management. Indeed, considerable progress in stroke care is evident nowadays, in part owing to better prevention and the increasing use of acute stroke units, urgent triage, multimodal CT- or MRI-based brain imaging, and IV and endovascular reperfusion therapy.
Source: Neurology - September 30, 2013 Category: Neurology Authors: Tanne, D., Koton, S., Bornstein, N. M. Tags: All Health Services Research, Outcome research, All Cerebrovascular disease/Stroke, All epidemiology GLOBAL PERSPECTIVES Source Type: research

Classifying Patients with Spatial Neglect by "Aiming" Versus "Where" Spatial Bias May Explain Differential Response to Bromocriptine Treatment (P03.261)
CONCLUSIONS: Classifying spatial neglect may be vital to interpreting rehabilitation outcomes and treatment studies. In this group study, larger than those performed previously, patients with "aiming" bias appeared to respond favorably to bromocriptine. However, "aiming" neglect patients may also have had milder neglect than those with "where" bias. Therefore, identifying "aiming" bias may also identify milder forms of neglect likely to respond to bromocriptine. Future studies with more bias-characterized patients are indicated.Disclosure: Dr. Chaudhari has nothing to disclose. Dr. Shah has nothing to disclose. Dr. Goedert...
Source: Neurology - February 14, 2013 Category: Neurology Authors: Chaudhari, A., Shah, P., Goedert, K., Adler, U., Barrett, A. Tags: P03 Neural Repair Source Type: research

Cognitive deficits of pure subcortical vascular dementia vs Alzheimer disease: PiB-PET-based study
Conclusions: Patients with PiB(–) SVaD were better at memory but worse at frontal function than patients with PiB(+) AD. The differences in memory/frontal functions observed between the 2 groups, however, could not differentiate all individual data due to some overlap in the cutoff threshold.
Source: Neurology - February 4, 2013 Category: Neurology Authors: Yoon, C. W., Shin, J. S., Kim, H. J., Cho, H., Noh, Y., Kim, G. H., Chin, J. H., Oh, S. J., Kim, J. S., Choe, Y. S., Lee, K.-H., Lee, J.-H., Seo, S. W., Na, D. L. Tags: All Cognitive Disorders/Dementia, Vascular dementia, Cognitive neuropsychology in dementia, Assessment of cognitive disorders/dementia ARTICLE Source Type: research

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