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Source: Atherosclerosis
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Total 65 results found since Jan 2013.
Predictive Accuracy of Stroke Risk Prediction Models Across Black and White Race, Sex, and Age Groups
CONCLUSIONS AND RELEVANCE: In this analysis of Black and White individuals without stroke or transient ischemic attack among 4 US cohorts, existing stroke-specific risk prediction models and novel machine learning techniques did not significantly improve discriminative accuracy for new-onset stroke compared with the pooled cohort equations, and the REGARDS self-report model had the best calibration. All algorithms exhibited worse discrimination in Black individuals than in White individuals, indicating the need to expand the pool of risk factors and improve modeling techniques to address observed racial disparities and imp...
Source: Atherosclerosis - January 24, 2023 Category: Cardiology Authors: Chuan Hong Michael J Pencina Daniel M Wojdyla Jennifer L Hall Suzanne E Judd Michael Cary Matthew M Engelhard Samuel Berchuck Ying Xian Ralph D'Agostino George Howard Brett Kissela Ricardo Henao Source Type: research
Artificial intelligence-based preventive, personalized and precision medicine for cardiovascular disease/stroke risk assessment in rheumatoid arthritis patients: a narrative review
Rheumatol Int. 2023 Aug 30. doi: 10.1007/s00296-023-05415-1. Online ahead of print.ABSTRACTThe challenges associated with diagnosing and treating cardiovascular disease (CVD)/Stroke in Rheumatoid arthritis (RA) arise from the delayed onset of symptoms. Existing clinical risk scores are inadequate in predicting cardiac events, and conventional risk factors alone do not accurately classify many individuals at risk. Several CVD biomarkers consider the multiple pathways involved in the development of atherosclerosis, which is the primary cause of CVD/Stroke in RA. To enhance the accuracy of CVD/Stroke risk assessment in the RA...
Source: Atherosclerosis - August 30, 2023 Category: Cardiology Authors: Mustafa Al-Maini Mahesh Maindarkar George D Kitas Narendra N Khanna Durga Prasanna Misra Amer M Johri Laura Mantella Vikas Agarwal Aman Sharma Inder M Singh George Tsoulfas John R Laird Gavino Faa Jagjit Teji Monika Turk Klaudija Viskovic Zoltan Ruzsa Sop Source Type: research
Cardiovascular/Stroke Risk Assessment in Patients with Erectile Dysfunction-A Role of Carotid Wall Arterial Imaging and Plaque Tissue Characterization Using Artificial Intelligence Paradigm: A Narrative Review
Diagnostics (Basel). 2022 May 17;12(5):1249. doi: 10.3390/diagnostics12051249.ABSTRACTPURPOSE: The role of erectile dysfunction (ED) has recently shown an association with the risk of stroke and coronary heart disease (CHD) via the atherosclerotic pathway. Cardiovascular disease (CVD)/stroke risk has been widely understood with the help of carotid artery disease (CTAD), a surrogate biomarker for CHD. The proposed study emphasizes artificial intelligence-based frameworks such as machine learning (ML) and deep learning (DL) that can accurately predict the severity of CVD/stroke risk using carotid wall arterial imaging in ED ...
Source: Atherosclerosis - May 28, 2022 Category: Cardiology Authors: Narendra N Khanna Mahesh Maindarkar Ajit Saxena Puneet Ahluwalia Sudip Paul Saurabh K Srivastava Elisa Cuadrado-Godia Aditya Sharma Tomaz Omerzu Luca Saba Sophie Mavrogeni Monika Turk John R Laird George D Kitas Mostafa Fatemi Al Baha Barqawi Martin Miner Source Type: research
Quantitative CTA vascular calcification, atherosclerosis burden, and stroke mechanism in patients with ischemic stroke
CONCLUSION: Atherosclerosis calcium volumes in major vessels were significantly higher in LAA compared to non-LAA stroke in younger age.PMID:37148773 | DOI:10.1016/j.jns.2023.120667
Source: Atherosclerosis - May 6, 2023 Category: Cardiology Authors: Takashi Shimoyama Sibaji Gaj Kunio Nakamura Shivakrishna Kovi Shumei Man Ken Uchino Source Type: research
Preventing post-stroke dementia. The MARCH Trial. Protocol and statistical analysis plan of a randomized clinical trial testing the safety and efficacy of Maraviroc in post-stroke cognitive impairment
CONCLUSIONS: The results of this work could lead to a novel, readily available, therapeutic avenue to reduce PSCI, and possibly other pathologies. This study will test safety and effectiveness of Maraviroc in limiting cognitive deterioration and/or post stroke cognitive impairment in patients with cerebral small vessel disease.SCHEDULE: First-patient first-visit was May 2021. Recruitment to complete in 2023, follow-up to complete in 2024.PMID:36082248 | PMC:PMC9446318 | DOI:10.1177/23969873221098857
Source: Atherosclerosis - September 9, 2022 Category: Cardiology Authors: Einor Ben Assayag Jeremy Molad Estelle Seyman Ofer Rotschild Ehud Zeltzer Udi Sadeh-Gonik Noa Bregman Aviva Alpernas Yahel Segal Dafna Ben Bashat Talya Nathan Muhamad Hawwari Oren Tene Hen Hallevi Source Type: research
Heterogeneity in diagnosis and prognosis of ischaemic stroke subtypes: 9-year follow-up of 22000 cases in Chinese adults
CONCLUSIONS: This study highlighted substantial heterogeneity in prognosis of IS subtypes and utility of ML approaches for classification of IS cases with incomplete clinical investigations.PMID:36847304 | DOI:10.1177/17474930231162265
Source: Atherosclerosis - February 27, 2023 Category: Cardiology Authors: Matthew Chun Haiqiang Qin Iain Turnbull Sam Sansome Simon Gilbert Alex Hacker Neil Wright Tingting Zhu David Clifton Derrick Bennett Yu Guo Pei Pei Jun Lv Canqing Yu Ling Yang Liming Li Yan Lu Zhengming Chen Ben Cairns Yiping Chen Robert Clarke Source Type: research
The association of stroke risk factors with the future thickness of carotid atherosclerotic plaques
DISCUSSION: The effect of each predictor on plaque thickness is complicated by interactions with other risk factors, particularly for the left carotid artery. The side of carotid artery involvement should be considered for stroke prevention.PMID:37125820 | DOI:10.1080/01616412.2023.2208484
Source: Atherosclerosis - May 1, 2023 Category: Cardiology Authors: Tanya Mohammadi Zahra Hooshanginezhad Babak Mohammadi Sina Dolatshahi Source Type: research
A comparative effectiveness study of carotid intervention for long-term stroke prevention in patients with severe asymptomatic stenosis from a large integrated health system
CONCLUSIONS: In this contemporary cohort study of patients with ACS utilizing rigorous analytic methodology, CEA appears to have a small but statistically significant effect on stroke prevention out to 8 years. Further study is needed to appropriately select the subset of patients most likely to benefit from intervention.PMID:37406943 | DOI:10.1016/j.jvs.2023.06.024
Source: Atherosclerosis - July 5, 2023 Category: Cardiology Authors: Robert W Chang Noel Pimentel Lue-Yen Tucker Kara A Rothenberg Andrew L Avins Alexander C Flint Rishad M Faruqi Mai N Nguyen-Huynh Romain Neugebauer Source Type: research
Causative Classification of Ischemic Stroke by the Machine Learning Algorithm Random Forests
CONCLUSION: The proposed RF model could be a useful diagnostic tool to help neurologists categorize etiologies of stroke.CLINICAL TRIAL REGISTRATION: [www.ClinicalTrials.gov], identifier [NCT01274117].PMID:35493925 | PMC:PMC9051333 | DOI:10.3389/fnagi.2022.788637
Source: Atherosclerosis - May 2, 2022 Category: Cardiology Authors: Jianan Wang Xiaoxian Gong Hongfang Chen Wansi Zhong Yi Chen Ying Zhou Wenhua Zhang Yaode He Min Lou Source Type: research
