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Condition: Huntington's Disease
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Total 17 results found since Jan 2013.

Structure-Based Virtual Screening to Identify Negative Allosteric Modulators of NMDA
CONCLUSION: The product of the study are compounds which have been validated through pharmacophore and score-based screening and MD simulation techniques to be allosterically inhibiting NMDA receptors and with favorable pharmacokinetic profile are likely to be therapeutic agents ready for in-vitro and in-vivo testing.PMID:35249502 | DOI:10.2174/1573406418666220304224150
Source: Medicinal Chemistry - March 7, 2022 Category: Chemistry Authors: Zaid Anis Sherwani Ruqaiya Khalil Mohammad Nur-E-Alam Sarfaraz Ahmed Zaheer Ul-Haq Source Type: research

Is exercise actually good for the brain?
There are plenty of reasons to get off your duff and exercise—but is improving your brain one of them? The U.S. Centers for Disease Control and Prevention touts exercise as a way to “ boost brain health , ” while the World Health Organization suggests that about 2 hours of moderate activity or 75 minutes of vigorous activity per week can help improve thinking and memory skills . But new research reveals a more complex picture. One recent review of the literature suggests the studies tying exercise to brain health may have important limitations , including small sample sizes. Othe...
Source: ScienceNOW - June 30, 2023 Category: Science Source Type: news