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Quick magnesium treatment fails to improve stroke outcomes, but study has silver lining
In the first study of its kind, a consortium led by UCLA physicians found that giving stroke patients intravenous magnesium within an hour of the onset of symptoms does not improve stroke outcomes.   However, the 8-year trial did find that with the help of paramedics in the field, intravenous medications can frequently be administered to stroke victims within that so-called "golden hour," during which they have the best chance to survive and avoid debilitating, long-term neurological damage.   The latter finding is a "game-changer," said Dr. Jeffrey Saver, director of the UCLA Stroke Center and a professor of ...
Source: UCLA Newsroom: Health Sciences - February 13, 2014 Category: Universities & Medical Training Source Type: news

Ultrasound imaging in teaching cardiac physiology
This laboratory session provides hands-on experience for students to visualize the beating human heart with ultrasound imaging. Simple views are obtained from which students can directly measure important cardiac dimensions in systole and diastole. This allows students to derive, from first principles, important measures of cardiac function, such as stroke volume, ejection fraction, and cardiac output. By repeating the measurements from a subject after a brief exercise period, an increase in stroke volume and ejection fraction are easily demonstrable, potentially with or without an increase in left ventricular end-diastoli...
Source: AJP: Advances in Physiology Education - July 20, 2016 Category: Universities & Medical Training Authors: Johnson, C. D., Montgomery, L. E. A., Quinn, J. G., Roe, S. M., Stewart, M. T., Tansey, E. A. Tags: HOW WE TEACH: CLASSROOM AND LABORATORY RESEARCH PROJECTS Source Type: research

Ultrasound imaging in teaching cardiac physiology.
Abstract This laboratory session provides hands-on experience for students to visualize the beating human heart with ultrasound imaging. Simple views are obtained from which students can directly measure important cardiac dimensions in systole and diastole. This allows students to derive, from first principles, important measures of cardiac function, such as stroke volume, ejection fraction, and cardiac output. By repeating the measurements from a subject after a brief exercise period, an increase in stroke volume and ejection fraction are easily demonstrable, potentially with or without an increase in left ventri...
Source: Adv Physiol Educ - July 25, 2016 Category: Universities & Medical Training Authors: Johnson CD, Montgomery LE, Quinn JG, Roe SM, Stewart MT, Tansey EA Tags: Adv Physiol Educ Source Type: research

Pesticides and Parkinson's: UCLA researchers uncover further proof of a link
For several years, neurologists at UCLA have been building a case that a link exists between pesticides and Parkinson's disease. To date, paraquat, maneb and ziram — common chemicals sprayed in California's Central Valley and elsewhere — have been tied to increases in the disease, not only among farmworkers but in individuals who simply lived or worked near fields and likely inhaled drifting particles.   Now, UCLA researchers have discovered a link between Parkinson's and another pesticide, benomyl, whose toxicological effects still linger some 10 years after the chemical was banned by the U.S. Environment...
Source: UCLA Newsroom: Health Sciences - January 3, 2013 Category: Universities & Medical Training Source Type: news

Researchers ID more pesticides linked to Parkinson's, gene that increases risk
This report provides evidence for the relevance of ALDH inhibition in Parkinson's disease pathogenesis, identifies pesticides that should be avoided to reduce the risk of developing Parkinson's disease and suggests that therapies modulating ALDH enzyme activity or otherwise eliminating toxic aldehydes should be developed and tested to potentially reduce Parkinson's disease occurrence or slow its progression, particularly for patients exposed to pesticides," the study states.   The study was funded in part by the National Institute of Environmental Health Sciences (P01ES016732, R01ES010544, 5R21ES16446-2 and U54ES0120...
Source: UCLA Newsroom: Health Sciences - February 3, 2014 Category: Universities & Medical Training Source Type: news

Integrating resident‐to‐resident teaching in interdisciplinary stroke education
Source: Medical Education - April 9, 2014 Category: Universities & Medical Training Authors: Analiz Rodriguez, Roy Strowd, Patrick Reynolds, Cedric Lefebvre Tags: Really Good Stuff: Lessons learned through innovation in medical education Source Type: research

Using stimulation of the diving reflex in humans to teach integrative physiology
During underwater submersion, the body responds by conserving O2 and prioritizing blood flow to the brain and heart. These physiological adjustments, which involve the nervous, cardiovascular, and respiratory systems, are known as the diving response and provide an ideal example of integrative physiology. The diving reflex can be stimulated in the practical laboratory setting using breath holding and facial immersion in water. Our undergraduate physiology students complete a laboratory class in which they investigate the effects of stimulating the diving reflex on cardiovascular variables, which are recorded and calculated...
Source: AJP: Advances in Physiology Education - November 29, 2014 Category: Universities & Medical Training Authors: Choate, J. K., Denton, K. M., Evans, R. G., Hodgson, Y. Tags: SOURCEBOOK OF LABORATORY ACTIVITIES IN PHYSIOLOGY Source Type: research

Taking Risk: Early Results From Teaching Hospitals’ Participation in the Center for Medicare and Medicaid Innovation Bundled Payments for Care Improvement Initiative
The authors describe observations from the 27 teaching hospitals constituting the Association of American Medical Colleges (AAMC) cohort in the Center for Medicare and Medicaid Innovation (CMMI) Bundled Payments for Care Improvement (BPCI) initiative. CMMI introduced BPCI in August 2011 and selected the first set of participants in January 2013. BPCI participants enter into Medicare payment arrangements for episodes of care for which they take financial risk. The first round of participants entered risk agreements on October 1, 2013 and January 1, 2014. In April 2014, CMMI selected additional participants who started takin...
Source: Academic Medicine - June 30, 2016 Category: Universities & Medical Training Tags: Articles Source Type: research

UCLA helps many to live long and prosper
In Westwood, more than 100 faculty experts from 25 departments have embarked on anall-encompassing push to cut the health and economic impacts of depression in half by the year 2050. The mammoth undertaking will rely on platforms developed by the new Institute for Precision Health, which will harness the power of big data and genomics to move toward individually tailored treatments and health-promotion strategies.On the same 419 acres of land, researchers across the spectrum, from the laboratory bench to the patient bedside, are ushering in a potentially game-changing approach to turning the body ’s immune defenses again...
Source: UCLA Newsroom: Health Sciences - November 9, 2017 Category: Universities & Medical Training Source Type: news

How to stay healthy and happy through the decades
Successful aging can be the norm, says UCLA psychology professor Alan Castel in his new book, “Better with Age: The Psychology of Successful Aging” (Oxford University Press). Castel sees many inspiring role models of aging. French Impressionist Claude Monet, he notes, began his beloved water lily paintings at age 73.Castel cites hundreds of research studies, including his own, combined with personal accounts from older Americans, including Maya Angelou, Warren Buffett, John Wooden, Bob Newhart, Frank Gehry, David Letterman, Jack LaLanne, Jared Diamond, Kareem Abdul-Jabbar, John Glenn and Vin Scully.Castel notes that ar...
Source: UCLA Newsroom: Health Sciences - November 1, 2018 Category: Universities & Medical Training Source Type: news

UCLA raises $611 million in 2020 –21, supporting students and advancing critical research
UCLA raised more than $611 million in gifts and pledges in the fiscal year ending June 30, exceeding its annual goal and drawing donors from all 50 states and 72 countries.“Generous donors at all levels have continued to partner with UCLA to effect meaningful change on campus, in the community and around the world,” said Chancellor Gene Block. “Despite a challenging year, our friends have once again demonstrated their extraordinary commitment to UCLA’s mission of education, research and service.”In response to conditions created by the COVID-19 pandemic, many donors focused on students ’ need to adapt to distan...
Source: UCLA Newsroom: Health Sciences - October 4, 2021 Category: Universities & Medical Training Source Type: news

Arterial Demonstration Device Illustrates Core Physiological Concepts
FASEB J. 2022 May;36 Suppl 1. doi: 10.1096/fasebj.2022.36.S1.R4868.ABSTRACTWe have created a hand-held, interactive arterial demonstration device that simplifies the teaching of several core physiological concepts. The device consists of low breaking point one-way spirometer valve coupled serially to a flow-through latex balloon that is fitted distally with a flow restrictor. The spirometer valve models the aortic valve; the latex balloon models the elastic arteries; the restrictor valve models the peripheral resistance. The user blows vigorously and intermittently into the proximal end of the device, modeling the ventricl...
Source: Adv Physiol Educ - May 13, 2022 Category: Universities & Medical Training Authors: Terrence E Sweeney Source Type: research

New UArizona study links brain waves directly to memory
The findings could lay foundations for cognitive impairment therapy and help improve memory. Niranjana Rajalakshmi Today University CommunicationsOscillations feature.jpgHealthCollege of ScienceExpertsResearch Media contact(s)Niranjana Rajalakshmi Science Writer, University Communicationsniranjanar@arizona.edu917-415-3497 Researcher contact(s)Arne Ekstrom Department of Psychologyadekstrom@email.arizona.edu520-621-4594Neurons produce rhythmic patterns of electrical activity in the brain. One of the unsettled questions in the field of neuroscience is what primarily drives these rhythmic signals, called oscillations. U...
Source: The University of Arizona: Health - July 31, 2023 Category: Universities & Medical Training Authors: niranjanar Source Type: research