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Total 226 results found since Jan 2013.

Cost of poor adherence to anti-hypertensive therapy in five European countries
This study is the first attempt to estimate the economic impact of non-adherence amongst patients with diagnosed hypertension in Europe, using data from five European countries (Italy, France, Germany, Spain and England).
Source: The European Journal of Health Economics - January 1, 2015 Category: Health Management Source Type: research

Impact of Human Development Index on the profile and outcomes of patients with acute coronary syndrome
Conclusions Clinical patient profiles differed substantially by country HDI groupings. Lower unadjusted event rates in medium-HDI countries may be explained by younger age and lower comorbidity burden among these countries’ patients. This heterogeneity in patient recruitment across country HDI groupings may have important implications for future global ACS trial design. Trial registration number NCT00699998.
Source: Heart - January 29, 2015 Category: Cardiology Authors: Roy, A., Roe, M. T., Neely, M. L., Cyr, D. D., Zamoryakhin, D., Fox, K. A. A., White, H. D., Armstrong, P. W., Ohman, E. M., Prabhakaran, D. Tags: Open access, Editor's choice, Drugs: cardiovascular system, Acute coronary syndromes Healthcare delivery, economics and global health Source Type: research

Use of the Berg Balance Scale to predict independent gait after stroke: a study of an inpatient population in Japan - Makizako H, Kabe N, Takano A, Isobe K.
OBJECTIVE: To examine whether the Berg Balance Scale (BBS) on admission and changes in it after one month predict the Functional Independence Measure (FIM) walking level 6 or 7 (modified independent and independent gait respectively) after 3 months and to ...
Source: SafetyLit: All (Unduplicated) - February 5, 2015 Category: Global & Universal Tags: Economics of Injury and Safety, PTSD, Injury Outcomes Source Type: news

Overweight and obesity on the island of Ireland: an estimation of costs
Conclusions The costs are substantial, and urgent public health action is required in Ireland to address the problem of increasing prevalence of overweight and obesity, which if left unchecked will lead to unsustainable cost escalation within the health service and unacceptable societal costs.
Source: BMJ Open - March 16, 2015 Category: Journals (General) Authors: Dee, A., Callinan, A., Doherty, E., O'Neill, C., McVeigh, T., Sweeney, M. R., Staines, A., Kearns, K., Fitzgerald, S., Sharp, L., Kee, F., Hughes, J., Balanda, K., Perry, I. J. Tags: Open access, Epidemiology, Health economics Research Source Type: research

Lung cancer CT screening is cost-effective but implementation matters
Commentary on: Black WC, Gareen IF, Soneji SS, et al.; National Lung Screening Trial Research Team. Cost-effectiveness of CT screening in the National Lung Screening Trial. N Engl J Med 2014;37:1793–802. Context The National Lung Screening Trial (NLST) revealed a 20% reduction in lung cancer mortality from three annual low-dose CT screening scans compared with chest radiographs in high-risk individuals.1 Since up to 10 million individuals in the USA may qualify for annual CT screening, policymakers have legitimately questioned whether the benefits of lung cancer screening justify the potential high costs of large-sca...
Source: Evidence-Based Medicine - March 17, 2015 Category: Internal Medicine Authors: Goulart, B. Tags: Smoking and tobacco, Health policy, Epidemiologic studies, Stroke, Screening (oncology), Radiology, Clinical diagnostic tests, Radiology (diagnostics), Screening (epidemiology), Health economics, Health service research, Health education, Screening (publi Source Type: research

Study finds obese people may struggle to reach a healthy weight
ConclusionThis research makes use of a general practice database providing just under 10 years of BMI observations for a large, nationally representative UK sample. It demonstrates that low proportions of people in the obese categories were able to achieve a normal BMI over a year of follow-up, and the common problem of weight cycling. However, there are points to consider when interpreting these results: The probability of obtaining a normal BMI over a year was very low: only 1 in 210 for men and 1 in 124 for women in the "simple obese" category of 30 to 35kg/m2, and much lower than that for the higher categor...
Source: NHS News Feed - July 20, 2015 Category: Consumer Health News Tags: Food/diet Obesity Source Type: news

Ezetimibe provides incremental reduction in risk for cardiovascular events and need for revascularisation following an acute coronary syndrome
Commentary on: Cannon CP, Blazing MA, Giugliano RP, et al., IMPROVE-IT Investigators. Ezetimibe Added to Statin Therapy after Acute Coronary Syndromes. N Engl J Med 2015;372:2387–97. Context Use of statin therapy to treat dyslipidemia in patients with established coronary artery disease is the standard of care worldwide. Given the negative results of a number of trials that tested the use of adjuvant lipid-lowering therapies against a statin background, there has been great scepticism about whether or not non-statin drugs provide incremental benefit.1–3 Ezetimibe inhibits the absorption of both dietary and bili...
Source: Evidence-Based Medicine - September 24, 2015 Category: Internal Medicine Authors: Toth, P. P. Tags: Health policy, Epidemiologic studies, Genetics, Immunology (including allergy), Vaccination / immunisation, Stroke, Diet, Ischaemic heart disease, Health economics, Health service research, Lipid disorders Therapeutics/Prevention Source Type: research

Economics of Team-based Care in Controlling Blood Pressure
Conclusions Team-based care to improve blood pressure control is cost effective based on evidence that 26 of 28 estimates of $/QALY gained from ten studies were below a conservative threshold of $50,000. This finding is salient to recent U.S. healthcare reforms and coordinated patient-centered care through formation of Accountable Care Organizations.
Source: American Journal of Preventive Medicine - October 15, 2015 Category: Global & Universal Source Type: research

Current 10-year atherosclerotic cardiovascular disease risk threshold for statin eligibility is cost-effective for primary prevention
Commentary on: Pandya A, Sy S, Cho S, et al. Cost effectiveness of 10-year risk thresholds for initiation of statin therapy for primary prevention of cardiovascular disease. JAMA 2015;314: 142–50 . Context The American College of Cardiology American Heart Association (ACC/AHA) cholesterol guidelines replaced the National Cholesterol Education Program Adult Treatment Panel III (NCEP/ATP III) in 2013,1 a change that was accompanied by significant controversy.2 Notable among the criticisms was that the pooled cohort equations (PCE) overestimates risk and coupled with the relatively lenient risk threshold (10-year PCE &g...
Source: Evidence-Based Medicine - November 24, 2015 Category: Internal Medicine Authors: Yeboah, J. Tags: Health policy, Epidemiologic studies, Drugs: cardiovascular system, Neuromuscular disease, Stroke, Ischaemic heart disease, Musculoskeletal syndromes, Health economics, Health service research Economic analysis Source Type: research

Work productivity loss and indirect costs associated with new cardiovascular events in high-risk patients with hyperlipidemia: estimates from population-based register data in Sweden
Conclusions Indirect costs related to work productivity losses of CV events are substantial in Swedish high-risk patients treated for hyperlipidemia and vary considerably by type of event.
Source: The European Journal of Health Economics - November 25, 2015 Category: Health Management Source Type: research

Needs of Internally Displaced Women and Children in Baghdad, Karbala, and Kirkuk, Iraq
Conclusions The vulnerability of this population is great, and the emotional trauma of multiple displacements, kidnapping and deaths from intentional violence is great. While some aid is reaching families, much more is needed. Though Iraq is a middle income country, reaching the IDPs in central Iraq will take much more in international assistance than is currently being received. Unfortunately, at this time of great need, assistance is being cut back throughout the region because of lack of funding.10 The local civil society organizations which have sprung up in many locations to assist IDPs, offer an avenue for targeting ...
Source: PLOS Currents Disasters - June 10, 2016 Category: Global & Universal Authors: Gilbert Burnham Source Type: research

Diagnosis and mortality in prehospital emergency patients transported to hospital: a population-based and registry-based cohort study - Christensen EF, Larsen TM, Jensen FB, Bendtsen MD, Hansen PA, Johnsen SP, Christiansen CF.
We examined the diag...
Source: SafetyLit - July 9, 2016 Category: Global & Universal Tags: Economics of Injury and Safety, PTSD, Injury Outcomes Source Type: news

The Importance of Talent and Chemistry in New Patient-First Business Models
Forward-thinking life sciences companies are shifting to new patient-centered business models, leaving the traditional volume-first approach behind. This move has tremendous implications, not only for patients but also for the current workforce and future talent: life sciences companies need to design new roles and rethink their talent strategies, including the ways they recruit, train, motivate and retain the best teams.The shift from volume to valueThe historical model in life sciences has been based on selling products, where more was better - more products, more market share and then more profits. Value-based reimburse...
Source: EyeForPharma - August 12, 2016 Category: Pharmaceuticals Authors: Jeff Elton Source Type: news

The Long ‐term Health Effects of Fetal Malnutrition: Evidence from the 1959–1961 China Great Leap Forward Famine
We report evidence of long‐term adverse health impacts of fetal malnutrition exposure of middle‐aged survivors of the 1959–1961 China Famine using data from the China Health and Retirement Longitudinal Study. We find that fetal exposure to malnutrition has large and long‐lasting impacts on both physical health and cognitive abilities, including the risks of suffering a stroke, physical disabilities in speech, walking and vision, and measures of mental acuity even half a century after the tragic event. Our findings imply that policies and programs that improve the nutritional status of pregnant women yield benefits ...
Source: Health Economics - August 18, 2016 Category: Health Management Authors: Seonghoon Kim, Belton Fleisher, Jessica Ya Sun Tags: Research Article Source Type: research

Relationship between walking capacity, biopsychosocial factors, self-efficacy, and walking activity in individuals poststroke - Danks KA, Pohlig RT, Roos M, Wright TR, Reisman DS.
BACKGROUND/PURPOSE: Many factors appear to be related to physical activity after stroke, yet it is unclear how these factors interact and which ones might be the best predictors. Therefore, the purpose of this study was twofold: (1) to examine the relation...
Source: SafetyLit - August 27, 2016 Category: Global & Universal Tags: Economics of Injury and Safety, PTSD, Injury Outcomes Source Type: news