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Condition: Ischemic Stroke
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Total 40393 results found since Jan 2013.

Hospitalized Infection as a Trigger for Acute Ischemic Stroke: The Atherosclerosis Risk in Communities Study Clinical Sciences
Conclusions— These results support the hypothesis that hospitalized infection is a trigger of ischemic stroke and may explain some cryptogenic strokes. Infection control efforts may prevent strokes. CVD preventive therapies may prevent strokes if used in the peri-infection period, but clinical trials are needed.
Source: Stroke - May 22, 2016 Category: Neurology Authors: Cowan, L. T., Alonso, A., Pankow, J. S., Folsom, A. R., Rosamond, W. D., Gottesman, R. F., Lakshminarayan, K. Tags: Epidemiology, Ischemic Stroke Clinical Sciences Source Type: research

Carotid Atherosclerosis and Stroke in Atrial Fibrillation: The Atherosclerosis Risk in Communities Study Brief Reports
Conclusions— Increased cIMT and presence of carotid plaque are associated with increased risk of ischemic stroke in individuals with AF. Furthermore, they may improve risk prediction of stroke, over and above the CHA2DS2-VASc score.
Source: Stroke - May 22, 2016 Category: Neurology Authors: Bekwelem, W., Jensen, P. N., Norby, F. L., Soliman, E. Z., Agarwal, S. K., Lip, G. Y. H., Pan, W., Folsom, A. R., Longstreth, W. T., Alonso, A., Heckbert, S. R., Chen, L. Y. Tags: Atrial Fibrillation, Risk Factors, Ischemic Stroke, Atherosclerosis Brief Reports Source Type: research

Thrombus Histology Suggests Cardioembolic Cause in Cryptogenic Stroke Clinical Sciences
Conclusions— Quantitative evaluation of thrombus composition may help to distinguish between different stroke causes. Our findings support the notion that the majority of cryptogenic strokes are cardioembolic.
Source: Stroke - June 26, 2016 Category: Neurology Authors: Boeckh-Behrens, T., Kleine, J. F., Zimmer, C., Neff, F., Scheipl, F., Pelisek, J., Schirmer, L., Nguyen, K., Karatas, D., Poppert, H. Tags: Cerebrovascular Disease/Stroke, Ischemic Stroke Clinical Sciences Source Type: research

High-Sensitive C-Reactive Protein Predicts Recurrent Stroke and Poor Functional Outcome: Subanalysis of the Clopidogrel in High-Risk Patients With Acute Nondisabling Cerebrovascular Events Trial Clinical Sciences
Conclusions— High hsCRP levels predict recurrent stroke and poor functional outcome in acute patients with minor stroke or transient ischemic attack. Clinical Trial Registration— URL: http://www.clinicaltrials.gov. Unique identifier: NCT00979589.
Source: Stroke - July 24, 2016 Category: Neurology Authors: Li, J., Zhao, X., Meng, X., Lin, J., Liu, L., Wang, C., Wang, A., Wang, Y., Wang, Y., on behalf of the CHANCE Investigators Tags: Biomarkers, Inflammation, Ischemic Stroke, Transient Ischemic Attack (TIA) Clinical Sciences Source Type: research

Antiphospholipid Antibodies and the Risk of Stroke in Urban and Rural Tanzania: A Community-Based Case-Control Study Clinical Sciences
Conclusions— The presence of lupus anticoagulant is a strong, and to date unrecognized, risk factor for stroke in Tanzania, especially in young and middle-aged individuals.
Source: Stroke - September 25, 2016 Category: Neurology Authors: de Mast, Q., Molhoek, J. E., van der Ven, A. J., Gray, W. K., de Groot, P. G., Jusabani, A., Mugusi, F., Urbanus, R. T., Walker, R. W. Tags: Etiology, Mechanisms, Pathophysiology, Cerebrovascular Disease/Stroke, Ischemic Stroke Clinical Sciences Source Type: research

Substantial Progress Yet Significant Opportunity for Improvement in Stroke Care in China Clinical Sciences
Conclusions—Adherence to stroke performance metrics has increased over time, but significant opportunities remain for further improvement. Continuous stroke quality improvement program should be developed as a national priority in China.
Source: Stroke - October 23, 2016 Category: Neurology Authors: Li, Z., Wang, C., Zhao, X., Liu, L., , Li, H., Shen, H., Liang, L., Bettger, J., Yang, Q., Wang, D., Wang, A., Pan, Y., Jiang, Y., Yang, X., Zhang, C., Fonarow, G. C., Schwamm, L. H., Hu, B., Peterson, E. D., Xian, Y., Wang, Y., Tags: Clinical Studies, Health Services, Quality and Outcomes, Cerebrovascular Disease/Stroke Original Contributions Source Type: research

Intravenous Thrombolysis in Unknown-Onset Stroke Clinical Sciences
Conclusions—Our data suggest no excess risk of symptomatic intracerebral hemorrhage but increased mortality and reduced favorable outcome in patients with UKO stroke compared with patients treated within the approved time window.
Source: Stroke - February 26, 2017 Category: Neurology Authors: Laura Dorado, Niaz Ahmed, Gotz Thomalla, Manuel Lozano, Branko Maloȷcic, Mushtaq Wani, Monica Millan, Ales Tomek, Antoni Davalos Tags: Cerebrovascular Disease/Stroke, Ischemic Stroke Original Contributions Source Type: research

Changes in the Employment Status and Risk of Stroke and Stroke Types Clinical Sciences
Conclusions—Job lost men and women and reemployed men had increased risks for both hemorrhagic and ischemic stroke incidence and mortality.
Source: Stroke - April 24, 2017 Category: Neurology Authors: Ehab S. Eshak, Kaori Honjo, Hiroyasu Iso, Ai Ikeda, Manami Inoue, Norie Sawada, Shoichiro Tsugane Tags: Epidemiology, Risk Factors, Cerebrovascular Disease/Stroke, Intracranial Hemorrhage, Ischemic Stroke Original Contributions Source Type: research

XBP1 (X-Box-Binding Protein-1)-Dependent O-GlcNAcylation Is Neuroprotective in Ischemic Stroke in Young Mice and Its Impairment in Aged Mice Is Rescued by Thiamet-G Basic Sciences
Conclusions—Our study indicates a critical role for the IRE1/XBP1 unfolded protein response branch in stroke outcome. O-GlcNAcylation is a prosurvival pathway that is activated in the stroke penumbra in young mice but impaired in aged mice. Boosting prosurvival pathways to counterbalance the age-related decline in the brain’s self-healing capacity could be a promising strategy to improve ischemic stroke outcome in aged brains.
Source: Stroke - May 22, 2017 Category: Neurology Authors: Meng Jiang, Shu Yu, Zhui Yu, Huaxin Sheng, Ying Li, Shuai Liu, David S. Warner, Wulf Paschen, Wei Yang Tags: Aging, Ischemic Stroke, Neuroprotectants Original Contributions Source Type: research

Confounding by Pre-Morbid Functional Status in Studies of Apparent Sex Differences in Severity and Outcome of Stroke Clinical Sciences
Conclusions—We found no evidence of a worse outcome of stroke in women when adjusting for age and pre-morbid mRS. Failure to account for sex differences in pre-morbid handicap could explain contradictory findings in previous studies. Properties of the mRS may also contribute to these inconsistencies.
Source: Stroke - September 25, 2017 Category: Neurology Authors: Christel Renoux, Janie Coulombe, Linxin Li, Aravind Ganesh, Louise Silver, Peter M. Rothwell Tags: Clinical Studies, Epidemiology, Women, Ischemic Stroke, Transient Ischemic Attack (TIA) Original Contributions Source Type: research

Burden of Intracranial Atherosclerosis Is Associated With Long-Term Vascular Outcome in Patients With Ischemic Stroke Clinical Sciences
Conclusions—ICAS burden was independently associated with the risk of subsequent composite vascular outcome in patients with ischemic stroke. These findings suggest that ICAS burden can reflect the risk of long-term vascular outcome.
Source: Stroke - September 25, 2017 Category: Neurology Authors: Byung-Su Kim, Pil-Wook Chung, Kwang-Yeol Park, Hong-Hee Won, Oh Young Bang, Chin-Sang Chung, Kwang Ho Lee, Gyeong-Moon Kim Tags: Cerebrovascular Disease/Stroke, Ischemic Stroke, Transient Ischemic Attack (TIA) Original Contributions Source Type: research

One-Year Outcomes After Minor Stroke or High-Risk Transient Ischemic Attack Clinical Sciences
Conclusions—Contemporary secondary stroke prevention strategies based on thorough diagnostic evaluation may contribute to the low subsequent vascular event rates observed in real-world clinical practice in Korea.
Source: Stroke - October 23, 2017 Category: Neurology Authors: Hong-Kyun Park, Beom Joon Kim, Moon-Ku Han, Jong-Moo Park, Kyusik Kang, Soo Joo Lee, Jae Guk Kim, Jae-Kwan Cha, Dae-Hyun Kim, Hyun-Wook Nah, Tai Hwan Park, Sang-Soon Park, Kyung Bok Lee, Jun Lee, Keun-Sik Hong, Yong-Jin Cho, Byung-Chul Lee, Kyung-Ho Yu, M Tags: Quality and Outcomes, Ischemic Stroke, Transient Ischemic Attack (TIA) Original Contributions Source Type: research

Substitution of Linoleic Acid for Other Macronutrients and the Risk of Ischemic Stroke Clinical Sciences
Conclusions—This study suggests that replacing saturated fatty acid, glycemic carbohydrate, or monounsaturated fatty acid with linoleic acid may be associated with a lower risk of ischemic stroke.
Source: Stroke - November 27, 2017 Category: Neurology Authors: Stine K. Veno, Erik B. Schmidt, Marianne U. Jakobsen, Soren Lundbye–Christensen, Flemming W. Bach, Kim Overvad Tags: Diet and Nutrition, Epidemiology, Ischemic Stroke Original Contributions Source Type: research

Stroke Incidence by Major Pathological Type and Ischemic Subtypes in the Auckland Regional Community Stroke Studies Clinical Sciences
Conclusions—A lack of change in IS and ICH incidence may reflect a trend toward increased incidence of younger strokes. Increased rates of large-artery atherosclerosis and small-vessel occlusion are associated with increased smoking and high blood pressure. Ethnic differences in the proportional distribution of pathological stroke subtypes suggest differential exposure and susceptibility to risk factors.
Source: Stroke - December 22, 2017 Category: Neurology Authors: Rita V. Krishnamurthi, Suzanne Barker-Collo, Varsha Parag, Priyakumari Parmar, Emma Witt, Amy Jones, Susan Mahon, Craig S. Anderson, P. Alan Barber, Valery L. Feigin Tags: Epidemiology, Cerebrovascular Disease/Stroke, Ischemic Stroke Original Contributions Source Type: research

Revised Framingham Stroke Risk Score, Nontraditional Risk Markers, and Incident Stroke in a Multiethnic Cohort Clinical Sciences
Conclusions—The R-FSRS downgraded stroke risk but had better calibration and discriminative ability for incident stroke compared with the original FSRS. Nontraditional risk markers modestly improved the discriminative ability of the R-FSRS, with coronary artery calcium performing the best.
Source: Stroke - January 22, 2018 Category: Neurology Authors: Peter Flueckiger, Will Longstreth, David Herrington, Joseph Yeboah Tags: Epidemiology, Primary Prevention, Race and Ethnicity, Risk Factors, Cerebrovascular Disease/Stroke Original Contributions Source Type: research