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Source: Stroke
Condition: Atrial Fibrillation

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Total 257 results found since Jan 2013.

Supraventricular Premature Beats and Short Atrial Runs Predict Atrial Fibrillation in Continuously Monitored Patients With Cryptogenic Stroke Brief Reports
Conclusions— Numerous SPBs and SVRs demonstrated a high risk for future AF in patients with cryptogenic stroke.
Source: Stroke - February 24, 2014 Category: Neurology Authors: Kochhauser, S., Dechering, D. G., Dittrich, R., Reinke, F., Ritter, M. A., Ramtin, S., Duning, T., Frommeyer, G., Eckardt, L. Tags: Electrocardiology, Embolic stroke Brief Reports Source Type: research

Antithrombotic Therapy After Acute Ischemic Stroke in Patients With Atrial Fibrillation Clinical Sciences
Conclusions— Contrary to current guidelines, 30% of patients with atrial fibrillation and recent IS are not prescribed any OAC therapy on discharge, whereas a further 30% are prescribed combination OAC and antiplatelet therapy. Combination OAC and antiplatelet therapy in patients at high cardiovascular risk requires evaluation in clinical trials, particularly with the newer OACs, given their more favorable risk–benefit ratio compared with warfarin.
Source: Stroke - November 24, 2014 Category: Neurology Authors: McGrath, E. R., Kapral, M. K., Fang, J., Eikelboom, J. W., Conghaile, A. O., Canavan, M., O'Donnell, M. J., on behalf of the Investigators of the Ontario Stroke Registry Tags: Secondary prevention, Acute Cerebral Infarction, Arrhythmias, clinical electrophysiology, drugs Clinical Sciences Source Type: research

Type of Anesthesia and Differences in Clinical Outcome After Intra-Arterial Treatment for Ischemic Stroke Clinical Sciences
Conclusions— Our study suggests that patients with AIS of the anterior circulation undergoing IAT without GA have a higher probability of good clinical outcome compared with patients treated with general anesthesia.
Source: Stroke - April 27, 2015 Category: Neurology Authors: van den Berg, L. A., Koelman, D. L. H., Berkhemer, O. A., Rozeman, A. D., Fransen, P. S. S., Beumer, D., Dippel, D. W., van der Lugt, A., van Oostenbrugge, R. J., van Zwam, W. H., Brouwer, P. A., Jenniskens, S., Boiten, J., Lycklama a Nijeholt, G. A., Vos Tags: Acute Cerebral Infarction, Emergency treatment of Stroke Clinical Sciences Source Type: research

Stroke and Embolic Events in Hypertrophic Cardiomyopathy: Risk Stratification in Patients Without Atrial Fibrillation Clinical Sciences
Conclusions— The incidence of stroke and embolic events was about 1.0% per year in the HCM cohort. AF had not been previously documented before the event in more than half of patients with events. Older age and enlarged left atrial dimension are possible risk factors for embolic events in patients with HCM without documented AF.
Source: Stroke - March 27, 2016 Category: Neurology Authors: Haruki, S., Minami, Y., Hagiwara, N. Tags: Cerebrovascular Disease/Stroke Clinical Sciences Source Type: research

Stroke in Duchenne Muscular Dystrophy: A Retrospective Longitudinal Study in 54 Patients Brief Reports
Conclusions— This study indicates an increased risk for ischemic strokes in DMD patients. Regular cardiological assessment of all DMD patients is mandatory to evaluate the individual risk profile for cardioembolic events and to adapt therapeutic strategies.
Source: Stroke - July 24, 2016 Category: Neurology Authors: Winterholler, M., Hollander, C., Kerling, F., Weber, I., Dittrich, S., Turk, M., Schroder, R. Tags: Cardiomyopathy, Ischemic Stroke Brief Reports Source Type: research

FABS: An Intuitive Tool for Screening of Stroke Mimics in the Emergency Department Clinical Sciences
Conclusions— FABS seems to be reliable in stratifying SM from acute cerebral ischemia cases among patients in whom the head computed tomography was negative for any acute findings. It can help clinicians consider advanced imaging for further diagnosis.
Source: Stroke - August 21, 2016 Category: Neurology Authors: Goyal, N., Tsivgoulis, G., Male, S., Metter, E. J., Iftikhar, S., Kerro, A., Chang, J. J., Frey, J. L., Triantafyllou, S., Papadimitropoulos, G., Abedi, V., Alexandrov, A. W., Alexandrov, A. V., Zand, R. Tags: Ischemic Stroke Clinical Sciences Source Type: research

Risk Factors and Cognitive Relevance of Cortical Cerebral Microinfarcts in Patients With Ischemic Stroke or Transient Ischemic Attack Clinical Sciences
Conclusions— Cortical CMIs are a common finding in patients with stroke/transient ischemic attack. Associations between CMI with atrial fibrillation and white matter hyperintensities suggest that these lesions have a heterogeneous cause, involving microembolism and cerebral small vessel disease. CMI seemed to preferentially impact visuospatial functions as assessed by a cognitive screening test.
Source: Stroke - September 25, 2016 Category: Neurology Authors: Wang, Z., van Veluw, S. J., Wong, A., Liu, W., Shi, L., Yang, J., Xiong, Y., Lau, A., Biessels, G. J., Mok, V. C. T. Tags: Cognitive Impairment, Ischemic Stroke Clinical Sciences Source Type: research

Geographic Variation in the Use of Oral Anticoagulation Therapy in Stroke Prevention in Atrial Fibrillation Brief Report
Conclusions—Large geographic variation exists in oral anticoagulation use in atrial fibrillation. The use of oral anticoagulation is lower in the South, where the rates of stroke are unusually high. In the future, it will be important to analyze whether the high rates of stroke in the South can be partially attributed to the underuse of oral anticoagulation in this region.
Source: Stroke - July 24, 2017 Category: Neurology Authors: Inmaculada Hernandez, Samir Saba, Yuting Zhang Tags: Arrhythmias, Anticoagulants, Health Services, Ischemic Stroke Brief Reports Source Type: research

Comparison of Clinical Risk Stratification for Predicting Stroke and Thromboembolism in Atrial Fibrillation Clinical Sciences
Conclusions— A direct comparison of 9 risk schemes reveals no profound differences in risk stratification accuracy for high-risk patients. Accurate prediction of low-risk patients is perhaps more valuable in determining those unlikely to benefit from oral anticoagulation therapy. Among our cohort, CHA2DS2-VASc performed best in this purpose.
Source: Stroke - January 27, 2014 Category: Neurology Authors: Aakre, C. A., McLeod, C. J., Cha, S. S., Tsang, T. S. M., Lip, G. Y. H., Gersh, B. J. Tags: Cerebrovascular disease/stroke, Arrhythmias, clinical electrophysiology, drugs, Embolic stroke, Anticoagulants Clinical Sciences Source Type: research

Atrial Premature Beats Predict Atrial Fibrillation in Cryptogenic Stroke: Results From the EMBRACE Trial Clinical Sciences
Conclusions— Among older cryptogenic stroke or transient ischemic attack patients, the number of APBs on a routine 24-hour Holter ECG was a strong dose-dependent independent predictor of prevalent subclinical AF. Those with frequent APBs have a high probability of AF and represent ideal candidates for prolonged ECG monitoring for AF detection. Clinical Trial Registration— URL: http://www.clinicaltrials.gov. Unique identifier: NCT00846924.
Source: Stroke - March 23, 2015 Category: Neurology Authors: Gladstone, D. J., Dorian, P., Spring, M., Panzov, V., Mamdani, M., Healey, J. S., Thorpe, K. E., for the EMBRACE Steering Committee and Investigators*, EMBRACE Steering Committee or Operations Committee, Aviv, Boyle, Blakely, Cote, Hall, Kapral, Kozlowski Tags: Electrocardiology, Arrhythmias, clinical electrophysiology, drugs, Embolic stroke Clinical Sciences Source Type: research

Microbleed Status and 3-Month Outcome After Intravenous Thrombolysis in 717 Patients With Acute Ischemic Stroke Clinical Sciences
Conclusions— Poor outcome or sICH was not associated with CMB presence or burden on pre–intravenous thrombolysis magnetic resonance imaging after adjustment for confounding factors. An individual patient data meta-analysis is needed to determine whether a subgroup of patients with CMBs carries an independent risk of poor outcome that might outweigh the expected benefit of intravenous thrombolysis.
Source: Stroke - August 24, 2015 Category: Neurology Authors: Turc, G., Sallem, A., Moulin, S., Tisserand, M., Machet, A., Edjlali, M., Baron, J.-C., Leclerc, X., Leys, D., Mas, J.-L., Cordonnier, C., Oppenheim, C. Tags: Acute Cerebral Infarction, Emergency treatment of Stroke, Computerized tomography and Magnetic Resonance Imaging, Intracerebral Hemorrhage, Thrombolysis Clinical Sciences Source Type: research

Endovascular Treatment for Acute Ischemic Stroke in the Setting of Anticoagulation Brief Reports
Conclusions— Intra-arterial therapy seems to be safe in patients taking OACs; however, our study showed a nonsignificant increase in hemorrhage and mortality with a nonsignificant decrease in good outcomes in comparison with non-OAC patients. Although these nominal differences may have been related to older age and more comorbidities in the OAC group, larger studies are needed to confirm our findings given our limited sample size.
Source: Stroke - November 23, 2015 Category: Neurology Authors: Rebello, L. C., Haussen, D. C., Belagaje, S., Anderson, A., Frankel, M., Nogueira, R. G. Tags: Anticoagulants, Cerebrovascular Disease/Stroke, Ischemic Stroke Brief Reports Source Type: research

Fibrin Clot Permeability as a Predictor of Stroke and Bleeding in Anticoagulated Patients With Atrial Fibrillation Clinical Sciences
Background and Purpose—Formation of denser fiber networks has been reported in atrial fibrillation and ischemic stroke. In this longitudinal cohort study, we evaluated whether fibrin clot density may predict thromboembolic and bleeding risk in patients with atrial fibrillation on vitamin K antagonists.Methods—In 236 patients with atrial fibrillation receiving vitamin K antagonists treatment, we measured ex vivo plasma clot permeability (Ks), a measure of the pore size in fibrin networks.Results—During a median follow-up of 4.3 (interquartile range, 3.7–4.8) years, annual rates of ischemic stroke or transient ischem...
Source: Stroke - September 25, 2017 Category: Neurology Authors: Leszek Drabik, Paweł Wołkow, Anetta Undas Tags: Atrial Fibrillation, Ischemic Stroke, Thrombosis Original Contributions Source Type: research

Multilocus Genetic Risk Score Associates With Ischemic Stroke in Case-Control and Prospective Cohort Studies Clinical Sciences
Conclusions— A multilocus GRS based on common variants for established cardiovascular risk factors was significantly associated with IS both in clinic-based samples and in the general population. However, the improvement in clinical risk prediction was found to be small.
Source: Stroke - January 27, 2014 Category: Neurology Authors: Malik, R., Bevan, S., Nalls, M. A., Holliday, E. G., Devan, W. J., Cheng, Y.-C., Ibrahim-Verbaas, C. A., Verhaaren, B. F. J., Bis, J. C., Joon, A. Y., de Stefano, A. L., Fornage, M., Psaty, B. M., Ikram, M. A., Launer, L. J., van Duijn, C. M., Sharma, P., Tags: Genetics of Stroke Clinical Sciences Source Type: research

Self-Report of Stroke, Transient Ischemic Attack, or Stroke Symptoms and Risk of Future Stroke in the Reasons for Geographic And Racial Differences in Stroke (REGARDS) Study Original Contributions
Conclusions— Results suggest a spectrum of risk from stroke symptoms to TIA, DS, and RS, and imply a need for establishing these categories in health screenings to manage risk for future stroke, reinforcing the clinical importance of stroke history including the presence of stroke symptoms.
Source: Stroke - December 24, 2012 Category: Neurology Authors: Judd, S. E., Kleindorfer, D. O., McClure, L. A., Rhodes, J. D., Howard, G., Cushman, M., Howard, V. J. Tags: Epidemiology Original Contributions Source Type: research