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Total 184 results found since Jan 2013.

Attention-deficit/hyperactivity disorder as a risk factor for cardiovascular diseases: a nationwide population-based cohort study
World Psychiatry. 2022 Oct;21(3):452-459. doi: 10.1002/wps.21020.ABSTRACTAccumulating evidence suggests a higher risk for cardiovascular diseases among individuals with mental disorders, but very little is known about the risk for overall and specific groups of cardiovascular diseases in people with attention-deficit/hyperactivity disorder (ADHD). To fill this knowledge gap, we investigated the prospective associations between ADHD and a wide range of cardiovascular diseases in adults. In a nationwide population-based cohort study, we identified 5,389,519 adults born between 1941 and 1983, without pre-existing cardiovascul...
Source: World Psychiatry - September 8, 2022 Category: Psychiatry Authors: Lin Li Zheng Chang Jiangwei Sun Miguel Garcia-Argibay Ebba Du Rietz Maja Dobrosavljevic Isabell Brikell Tomas Jernberg Marco Solmi Samuele Cortese Henrik Larsson Source Type: research

Association between history of attention-deficit/hyperactivity disorder diagnosis and cardiovascular disease in U.S. adults.
Conclusions: In a nationally representative sample of U.S. adults, we found a significant, positive association between a history of ADHD diagnosis and CVD. Further investigation is needed to replicate our findings and determine the underlying mechanisms. (PsycInfo Database Record (c) 2022 APA, all rights reserved)
Source: Health Psychology - July 18, 2022 Category: Psychiatry & Psychology Source Type: research

D-serine metabolism in the medial prefrontal cortex, but not the hippocampus, is involved in AD/HD-like behaviors in SHRSP/Ezo
Eur J Pharmacol. 2022 Mar 29:174930. doi: 10.1016/j.ejphar.2022.174930. Online ahead of print.ABSTRACTAttention-deficit/hyperactivity disorder (AD/HD) is a mild neurodevelopmental disorder with inattention, hyperactivity, and impulsivity as its core symptoms. We previously revealed that an AD/HD animal model, juvenile stroke-prone spontaneously hypertensive rats (SHRSP/Ezo) exhibited functional abnormalities in N-methyl-D-aspartate (NMDA) receptors in the prefrontal cortex. D-serine is an endogenous co-ligand that acts on the glycine-binding site of NMDA receptors, which is essential for the physiological activation of NMD...
Source: European Journal of Pharmacology - April 1, 2022 Category: Drugs & Pharmacology Authors: Tsugumi Shindo Hiroki Shikanai Akane Watarai Sachiko Hiraide Kenji Iizuka Takeshi Izumi Source Type: research

Frontal interhemispheric structural connectivity, attention, and executive function in children with perinatal stroke
Perinatal stroke affects ∼1 in 1000 births and concomitant cognitive impairments such as Attention Deficit/Hyperactivity Disorder (ADHD) and executive dysfunction can be disabling. We used diffusion tensor imaging (DTI) to investigate whether stroke-related differences in frontal white matter (WM) relate to cognitive impa irments. WM metrics correlated with parental ratings of ADHD and executive function suggesting that underlying microstructure of frontal white matter quantified via tractography may provide a relevant biomarker associated with cognition and behavior in children with perinatal stroke. AbstractPerinatal s...
Source: Brain and Behavior - November 26, 2021 Category: Neurology Authors: Nicole Larsen, Brandon T. Craig, Alicia J. Hilderley, Shane Virani, Kara Murias, Brian L. Brooks, Adam Kirton, Helen L. Carlson Tags: ORIGINAL ARTICLE Source Type: research