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MRI scan may help diagnose chronic traumatic encephalopathy, UCLA researchers report
UCLA doctors have found what may be an earlier and easier way to diagnose chronic traumatic encephalopathy, or CTE, a disorder that is thought to affect some former football players and others with a history of repetitive brain trauma. Using a new software tool for analyzing MRI scans, the researchers detected the shrinkage of several key brain regions in a former football player with cognitive problems. The same pattern of brain changes is commonly seen in CTE cases that have been confirmed by autopsies after a person’s death. While the findings from this single case report are preliminary, they raise the possibility th...
Source: UCLA Newsroom: Health Sciences - August 24, 2016 Category: Universities & Medical Training Source Type: news

Head injuries can alter hundreds of genes and lead to serious brain diseases, UCLA biologists report
Head injuries can harm hundreds of genes in the brain in a way that increases people ’s risk for a wide range of neurological and psychiatric disorders, UCLA life scientists report.The researchers identified for the first time master genes that they believe control hundreds of other genes which are linked to Alzheimer ’s disease, Parkinson’s disease, post-traumatic stress disorder, stroke, attention deficit hyperactivity disorder, autism, depression, schizophrenia and other disorders.Knowing what the master genes are could give scientists targets for new pharmaceuticals to treat brain diseases. Eventually, scientists...
Source: UCLA Newsroom: Health Sciences - March 6, 2017 Category: Universities & Medical Training Source Type: news

Rare genetic variants found to increase risk for Tourette syndrome
An international team led by researchers from UCLA and Massachusetts General Hospital has identified the first definitive genes associated with Tourette syndrome, giving scientists a long-sought foothold on the biology of the disease.The report in the June 21 issue of Neuron describes the discovery of rare mutations — either deletions or duplications of genetic material — in two neurodevelopmental genes, NRXN1 and CNTN6, in people with Tourette syndrome, a disorder characterized by multiple chronic, involuntary motor and vocal tics.“This is a first, key step in understanding the role of these genes in the disease pro...
Source: UCLA Newsroom: Health Sciences - June 21, 2017 Category: Universities & Medical Training Source Type: news