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Post-stroke shoulder pain: Nociceptive or neuropathic?
Acute rehabilitation after stroke can be adversely affected by complications such as pain in the hemiplegic shoulder. The onset of hemiplegic shoulder pain (HSP) can compromise functional gains, and has been shown to contribute to longer term disability . The first systematic study of the incidence of post-stroke shoulder pain (PSSP) found that 40% of patients were affected during the 3–6months following survival of a stroke . In 25% of patients, pain occurred during the first two weeks after stroke . The prognosis at six months, however, appears to be reasonably good, with 80% of patients reporting improvement or comple...
Source: Pain - November 26, 2012 Category: Anesthesiology Authors: Anthony K.P. Jones, Christopher A. Brown Tags: Commentaries Source Type: research

Animal models for central poststroke pain: a critical comprehensive review
Abstract: Central poststroke pain (CPSP) is a severe type of neuropathic pain that can develop after stroke and is difficult to treat. Research into its underlying mechanisms and treatment options could benefit from a valid CPSP animal model. Nine different CPSP animal models have been published, but there are relatively few reports on successful reproductions of these models and so far only little advances in the understanding or the management of CPSP have been made relying on these models. In general, the construct validity (similarity in underlying mechanisms) of these CPSP animal models is relatively high, although th...
Source: Pain - December 30, 2016 Category: Anesthesiology Tags: Comprehensive Review Source Type: research

Do chronic pain and comorbidities affect brain function in sickle cell patients? A systematic review of neuroimaging and treatment approaches
Sickle cell disease (SCD) is a medical condition in which chronic pain is common and negatively impacts psychosocial function and quality of life. Although the brain mechanisms underlying chronic pain are well studied in other painful conditions, the brain mechanisms underlying chronic pain and the associated psychosocial comorbidities are not well established in SCD. A growing literature demonstrates the effect of treatment of chronic pain, including pharmacological and nonpharmacological treatments, on brain function. The present systematic review aimed to (1) determine the effects of chronic pain and psychosocial comorb...
Source: Pain - August 21, 2019 Category: Anesthesiology Tags: Systematic Reviews and Meta-Analyses Source Type: research