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Benefit of initial dual-therapy on stroke prevention in Chinese hypertensive patients: a real world cohort study.
CONCLUSIONS: Our study demonstrates that, for patients with uncontrolled hypertension, initial dual therapy is more effective in the prevention of stroke during the first 6 months of treatment, but not thereafter. Combination antihypertensive therapy may be a beneficial initial strategy for early stroke prevention. PMID: 26101644 [PubMed]
Source: Journal of Thoracic Disease - June 26, 2015 Category: Respiratory Medicine Tags: J Thorac Dis Source Type: research

Sleep-disordered breathing and stroke: chicken or egg?
Authors: Alexiev F, Brill AK, Ott SR, Duss S, Schmidt M, Bassetti CL Abstract The bidirectional interaction between sleep-disordered breathing (SDB) and stroke has been the subject of many studies. On the one hand, different forms of SDB, and especially obstructive sleep apnea, increase the risk of stroke either directly or indirectly by influencing other known cardiovascular risk factors such as arterial hypertension and arrhythmias. On the other hand, stroke itself can cause either de novo appearance of SDB, aggravate a pre-existing SDB, or trigger a transition from one type of pathological SDB pattern into anoth...
Source: Journal of Thoracic Disease - January 29, 2019 Category: Respiratory Medicine Tags: J Thorac Dis Source Type: research

Study on the predictive ability of emergency CHADS < sub > 2 < /sub > score and CHA < sub > 2 < /sub > DS < sub > 2 < /sub > -VASc score for coronary artery disease and prognosis in patients with acute ST-segment elevation myocardial infarction
CONCLUSIONS: Multiple factors jointly affect the severity and prognosis of CAD in patients with acute STEMI. The CHA2DS2-VASc score is better than the CHADS2 score in predicting the severity of coronary artery lesions and prognosis of patients, providing theoretical support for clinical practice.PMID:35928606 | PMC:PMC9344425 | DOI:10.21037/jtd-22-763
Source: Journal of Thoracic Disease - August 5, 2022 Category: Respiratory Medicine Authors: Xin Huang Hong Lv Zeyan Liu Yuan Liu Xue Yang Source Type: research

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