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Condition: Hypertension
Cancer: Brain Cancers
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Total 139 results found since Jan 2013.
Tumor necrosis factor-{alpha} inhibition attenuates middle cerebral artery remodeling but increases cerebral ischemic damage in hypertensive rats
Hypertension causes vascular inflammation evidenced by an increase in perivascular macrophages and proinflammatory cytokines in the arterial wall. Perivascular macrophage depletion reduced tumor necrosis factor (TNF)-α expression in cerebral arteries of hypertensive rats and attenuated inward remodeling, suggesting that TNF-α might play a role in the remodeling process. We hypothesized that TNF-α inhibition would improve middle cerebral artery (MCA) structure and reduce damage after cerebral ischemia in hypertensive rats. Six-week-old male stroke-prone spontaneously hypertensive rats (SHRSP) were treated ...
Source: AJP: Heart and Circulatory Physiology - September 1, 2014 Category: Cardiology Authors: Pires, P. W., Girgla, S. S., Moreno, G., McClain, J. L., Dorrance, A. M. Tags: VASCULAR BIOLOGY AND MICROCIRCULATION Source Type: research
Peroxisome Proliferator-activated Receptor-γ Agonist Pioglitazone Ameliorates White Matter Lesion and Cognitive Impairment in Hypertensive Rats.
CONCLUSIONS: Long-term treatment of pioglitazone has beneficial effect on hypertension-induced WML and cognition decline, which may partly through its effect on attenuation of arteriolar remodeling, endothelial activation, and brain inflammation.
PMID: 25611692 [PubMed - as supplied by publisher]
Source: CNS Neuroscience and Therapeutics - January 22, 2015 Category: Neuroscience Authors: Lan LF, Zheng L, Yang X, Ji XT, Fan YH, Zeng JS Tags: CNS Neurosci Ther Source Type: research
7 Ways to Permanently Banish Belly Fat
Sixty-nine percent of Americans adults are overweight, and over 35 percent are obese. Obesity increases your risk for numerous conditions including heart disease, stroke, Type 2 diabetes, high blood pressure, and cancer.
Sadly, about 3.4 million adults die each year from being overweight or obese. Globally obesity now kills about the same as tobacco and all wars, terrorism and violence. Nearly all people who are overweight already have "pre-diabetes" and have significant risks of disease and death. They just don't know it.
When you begin to put on weight, especially lethal belly fat, your biology shifts out of balance, v...
Source: Healthy Living - The Huffington Post - February 27, 2015 Category: Consumer Health News Source Type: news
What can blood biomarkers tell us about cardiovascular risk in obstructive sleep apnea?
CONCLUSION: The results clearly demonstrate that the relationship between specific biomarkers and OSA is often influenced by age, gender or ethnicity, which has hindered the identification of a unique marker for the evaluation of all patients with OSA. Moreover, given the frequency of comorbidities in OSA, which, by themselves, increase the cardiovascular risk, all confounding factors must be considered in the evaluation of these biomarkers.
PMID: 25716745 [PubMed - as supplied by publisher]
Source: Sleep and Breathing - February 26, 2015 Category: Sleep Medicine Authors: de Araújo Freitas IG, de Bruin PF, Bittencourt L, de Bruin VM, Tufik S Tags: Sleep Breath Source Type: research
This Diet Could Cut Your Risk Of Alzheimer's By Up To 50 Percent
What if there was a preventative measure that could slash your risk of developing Alzheimer's disease by up to half?
Some nutritionists may have found it, in the form of a Mediterranean-based diet that's high in nutrients and low in sugar and unhealthy fats.
The brain-healthy (and fittingly named) MIND diet -- which stands for "Mediterranean-DASH Intervention for Neurodegenerative Delay" -- is effective even if it is not followed rigorously, according to a new study from Rush University. Researchers found that people who followed the diet closely had a 53 percent lower chance of developing Alzheimer's, and those who onl...
Source: Science - The Huffington Post - March 21, 2015 Category: Science Source Type: news
Atypical isolated nuclear oculomotor nerve syndrome: A diagnostic challenge (P1.031)
CONCLUSION: This report will raise the awareness about nuclear oculomotor nerve syndrome and lead to a potentially successful therapeutic approach.Disclosure: Dr. Liao has nothing to disclose. Dr. Kamiya Matsuoka has nothing to disclose.
Source: Neurology - April 8, 2015 Category: Neurology Authors: Kamiya Matsuoka, C., Liao, B. Tags: Cerebrovascular Disease and Interventional Neurology: Case Reports Source Type: research
7 Big Things We Learned About Sleep In The Past Decade
It's no secret that here at The Huffington Post, we love sleep -- and for good reason.
Sleep has been called the "third pillar" of health, along with nutrition and exercise. Getting the quality sleep that you need has the power to protect your physical and mental health, while skipping out on sleep can seriously hurt your health, cognition and well-being over time.
Over the past 10 years, sleep has finally become widely recognized as a critical aspect of good health, and new research has shed more light on its importance in our lives. Here's what we've learned.
1. A sleeping brain is an active brain.
While you're re...
Source: Science - The Huffington Post - May 25, 2015 Category: Science Source Type: news
Management of Intracranial Pressure
Purpose of Review:: Intracranial pressure (ICP) can be elevated in traumatic brain injury, large artery acute ischemic stroke, intracranial hemorrhage, intracranial neoplasms, and diffuse cerebral disorders such as meningitis, encephalitis, and acute hepatic failure. Raised ICP is also known as intracranial hypertension and is defined as a sustained ICP of greater than 20 mm Hg.
Recent Findings:: ICP must be measured through an invasive brain catheter, typically an external ventricular catheter that can drain CSF and measure ICP, or through an intraparenchymal ICP probe. Proper recognition of the clinical signs of elevated...
Source: CONTINUUM - October 1, 2015 Category: Neurology Tags: Review Articles Source Type: research
Exercise: You may need less than you think
Regular exercise is one of the cornerstones for maintaining good health. Regular physical activity helps to prevent heart and blood vessel disease, diabetes, dementia, and even some types of cancer. But while the health benefits of exercise are indisputable, there is still a question about exactly how much exercise is needed to promote optimal health.
According to a recent article in The Journal of the American Medical Association by Thijs Eijsvogels and Paul Thompson, the answer may be “not as much as you might think.”
Every little bit of exercise counts
Drs. Eijsvogels and Thompson reviewed several published studies ...
Source: New Harvard Health Information - December 8, 2015 Category: Consumer Health News Authors: Gregory Curfman, MD Tags: Diet and Weight Loss Exercise and Fitness Health Heart Health Hypertension and Stroke Prevention Source Type: news
More Doctors Are Prescribing Exercise Instead Of Medication
BOSTON (AP) — When Dr. Michelle Johnson scribbles out prescriptions, the next stop for many of her patients is the gym, not the pharmacy.
Doctors treating chronic health problems increasingly are prescribing exercise for their patients — and encouraging them to think of physical activity as their new medication.
In one such program run by a health center in Boston’s Roxbury neighborhood, primary care physicians, internists and psychologists prescribe access to a gym for $10 a month, including free child care, classes and kids programs. Providing affordable gym access for patients ensures compliance, said Gibbs Sa...
Source: WBZ-TV - Breaking News, Weather and Sports for Boston, Worcester and New Hampshire - March 15, 2016 Category: Consumer Health News Authors: deanreddington Tags: Health Local News Exercise Ken MacLeod Source Type: news
Daily low-dose aspirin may help combat cancer
Conclusion
The systematic review looked at 47 studies and attempted to combine the results, looking for evidence of a beneficial effect of low-dose aspirin on risk of death in people already diagnosed with cancer.
The few RCTs identified – the best-quality evidence – did not provide conclusive evidence that aspirin improves survival rates.
The rest of the studies were observational in nature, so cannot prove that aspirin reduces the risk of death from cancer. The only significant results were for a 24% reduction in risk of death from colon cancer, and a possible 11% reduced risk of death from prostate cancer. However,...
Source: NHS News Feed - April 22, 2016 Category: Consumer Health News Tags: Cancer Medication Source Type: news
Phytocannabinoids and cannabimimetic drugs: recent patents in central nervous system disorders.
CONCLUSIONS: Finally, although the study of the mechanisms of action of these compounds is still unsolved, many reports and patents strongly suggest therapeutic potential of these compounds in neurological diseases.
PMID: 27184693 [PubMed - as supplied by publisher]
Source: Recent Patents on CNS Drug Discovery - May 18, 2016 Category: Drugs & Pharmacology Tags: Recent Pat CNS Drug Discov Source Type: research
Ask JJ: Type 2 Diabetes
Dear JJ: My doctor just diagnosed me with pre-diabetes. Type 2 diabetes runs in my family, but I will not accept it as my fate. You've written about sugar's detrimental impact, so how can I get this under control so it doesn't blow up into full-blown diabetes?
Diabetes doesn't happen overnight or linearly, but when your metabolic machinery breaks, serious havoc ensues. The massive repercussions can become deadly.
Every time you eat, you raise blood sugar, which triggers your pancreas to release a hormone called insulin. Every food raises blood sugar, but high-sugar impact foods do it big time.
Your pancreas "secretes s...
Source: Healthy Living - The Huffington Post - June 16, 2016 Category: Consumer Health News Source Type: news
