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Infectious Disease: SARS

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Total 158 results found since Jan 2013.

A Potential Role of the CD47/SIRPalpha Axis in COVID-19 Pathogenesis
Curr Issues Mol Biol. 2021 Sep 22;43(3):1212-1225. doi: 10.3390/cimb43030086.ABSTRACTThe coronavirus SARS-CoV-2 is the cause of the ongoing COVID-19 pandemic. Most SARS-CoV-2 infections are mild or even asymptomatic. However, a small fraction of infected individuals develops severe, life-threatening disease, which is caused by an uncontrolled immune response resulting in hyperinflammation. However, the factors predisposing individuals to severe disease remain poorly understood. Here, we show that levels of CD47, which is known to mediate immune escape in cancer and virus-infected cells, are elevated in SARS-CoV-2-infected ...
Source: Current Issues in Molecular Biology - October 26, 2021 Category: Molecular Biology Authors: Katie-May McLaughlin Denisa Bojkova Joshua D Kandler Marco Bechtel Philipp Reus Trang Le Florian Rothweiler Julian U G Wagner Andreas Weigert Sandra Ciesek Mark N Wass Martin Michaelis Jindrich Cinatl Source Type: research

Outcomes in post-acute sequelae of COVID-19 (PASC) at 6 months post-infection Part 1: Cognitive functioning
CONCLUSIONS: The results were noteworthy for infrequent Impaired scores, and significant correlations between cognition and mood/anxiety measures, but not between cognitive performance and premorbid vascular risk factors, psychiatric diagnoses, or COVID-19 disease severity. Results suggest that psychological distress was prominent in PASC and related to objective cognitive performance, but objective cognitive performance was unrelated to cognitive complaints. Other contributing factors may include fatigue/sleep issues. Neurologically based cognitive deficits were not suggested by the results.During the COVID-19 pandemic, r...
Source: The Clinical Neuropsychologist - February 8, 2022 Category: Psychiatry & Psychology Authors: Douglas M Whiteside Michael R Basso Savana M Naini James Porter Erin Holker Eric J Waldron Tanya E Melnik Natalie Niskanen Sarah E Taylor Source Type: research