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Inflammatory and Metabolic Syndrome Biomarker Analysis of Vascular Outcomes in End-stage Renal Disease
Int J Angiol DOI: 10.1055/s-0036-1593409End-stage renal disease (ESRD) presents a complex syndrome in which inflammatory and metabolic processes contribute to disease progression and development of comorbid conditions. Over $1 trillion is spent globally on ESRD care.Plasma samples collected from 83 ESRD patients prior to hemodialysis were profiled for metabolic and inflammatory biomarker concentrations. Concentrations were compared between groups with and without history of stroke, acute coronary syndrome (ACS), congestive heart failure (CHF), and coronary artery disease (CAD).The 25 patients (30.1%) with history of stroke...
Source: International Journal of Angiology - October 4, 2016 Category: Cardiology Authors: Sweigert, Patrick J. Bansal, Vinod K. Hoppensteadt, Debra A. Saluk, Jennifer L. Syed, Daneyal A. Fareed, Jawed Tags: Original Article Source Type: research

Obesity or obesities? Controversies on the association between body mass index and premature mortality.
Abstract Obesity is still defined on the basis of body mass index (BMI) and BMI in itself is generally accepted as a strong predictor of overall early mortality. However, an inverse association between BMI and mortality has been reported in patients with many disease states and in several clinical settings: hemodialysis, cardiovascular diseases, hypertension, stroke, diabetes, chronic obstructive pulmonary disease, surgery, etc. This unexpected phenomenon is usually called obesity-survival paradox (OP). The contiguous concepts of metabolically healthy obesity (MHO, a phenotype having BMI ≥ 30 but not having an...
Source: Eating and weight disorders : EWD - April 3, 2016 Category: Eating Disorders and Weight Management Authors: Bosello O, Donataccio MP, Cuzzolaro M Tags: Eat Weight Disord Source Type: research

Exploring the role of lipoprotein(a) in cardiovascular diseases and diabetes in Chinese population
Int J Biol Macromol. 2023 Feb 7:123586. doi: 10.1016/j.ijbiomac.2023.123586. Online ahead of print.ABSTRACTA high level of lipoprotein (a) in the plasma has been associated with a variety of cardiovascular diseases and is considered to be an independent predictor of some other diseases. Based on recent studies, the concentration levels of Lp(a) in the Chinese population exhibit a distinctive variation from other populations. In the Chinese population, a high level of Lp(a) indicates a higher incidence of revascularization, platelet aggregation, and thrombogenicity following PCI. Increased risk of atherosclerotic cardiovasc...
Source: International Journal of Biological Macromolecules - February 9, 2023 Category: Biochemistry Authors: Zubair Hussain Hongcai Liu Junaid Iqbal Hou-De Zhou Source Type: research