Filtered By:
Source: European Journal of Heart Failure
Condition: Heart Failure
This page shows you your search results in order of date.
Order by Relevance | Date
Total 113 results found since Jan 2013.
Noncardiac comorbidities and intensive up ‐titration of oral treatment in patients recently hospitalized for heart failure: insights from the STRONG‐HF trial
ConclusionsIn the STRONG-HF trial, non-cardiac comorbidities neither limited the rapid up-titration of HF-therapies, nor attenuated the benefit of HIC on primary endpoint.In the context of a clinical trial, the benefit-risk ratio favors the rapid up-titration of HF-therapies even in patients with multiple NCCsThis article is protected by copyright. All rights reserved.
Source: European Journal of Heart Failure - September 21, 2023 Category: Cardiology Authors: Ovidiu Chioncel,
Beth Davison,
Marianna Adamo,
Laura E Antohi,
Mattia Arrigo,
Marianela Barros,
Jan Biegus,
Kamil ė Čerlinskaitė‐Bajorė,
Jelena Celutkiene,
Alain Cohen‐Solal,
Albertino Damasceno,
Rafael Diaz,
Christopher Edwards,
Gera Tags: Research Article Source Type: research
Impact of comorbidities on health status measured using the Kansas City Cardiomyopathy Questionnaire in patients with HFrEF and HFpEF
ConclusionsCardiac and non-cardiac comorbidities are common in both HFrEF and HFpEF patients and most are associated with reductions in health status although the impact varied among comorbidities, by the number of comorbidities, and by HF phenotype. Treating/correcting comorbidity is a therapeutic approach that may improve the health status of patients with HF.This article is protected by copyright. All rights reserved.
Source: European Journal of Heart Failure - July 4, 2023 Category: Cardiology Authors: Mingming Yang,
Toru Kondo,
Carly Adamson,
Jawad H. Butt,
William T. Abraham,
Akshay S. Desai,
Karola S. Jering,
Lars K øber,
Mikhail N. Kosiborod,
Milton Packer,
Jean L. Rouleau,
Scott D. Solomon,
Muthiah Vaduganathan,
Michael R. Zile,
Pard Tags: Research Article Source Type: research
Influenza vaccination and cardiovascular events in patients with ischaemic heart disease and heart failure: A meta ‐analysis
ConclusionIn this meta-analysis of available RCTs in patients at high cardiovascular risk, influenza vaccination was associated with a reduced incidence of cardiovascular events, cardiovascular death and all-cause death as compared to placebo or no treatment.
Source: European Journal of Heart Failure - June 28, 2023 Category: Cardiology Authors: Daniel Modin,
Mats Christian H øjbjerg Lassen,
Brian Claggett,
Niklas Dyrby Johansen,
Maryam Keshtkar‐Jahromi,
Kristoffer Grundtvig Skaarup,
Joshua Nealon,
Jacob A. Udell,
Orly Vardeny,
Scott D. Solomon,
Gunnar Gislason,
Tor Biering‐Søren Tags: Research Article Source Type: research
Impact of multimorbidity on mortality in heart failure with reduced ejection fraction: which comorbidities matter most? An analysis of PARADIGM ‐HF and ATMOSPHERE
ConclusionsIn HF, the impact of multimorbidity differed at the individual patient and population level, depending on the prevalence of and the risk related to each comorbidity, and the interaction between individual comorbidities. Patients with coexistent PAD and stroke were at greatest individual risk whereas, from a population perspective, coexistent CKD and hypertension mattered most.
Source: European Journal of Heart Failure - April 25, 2023 Category: Cardiology Authors: Pooja Dewan,
Jo ão Pedro Ferreira,
Jawad H. Butt,
Mark C. Petrie,
William T. Abraham,
Akshay S. Desai,
Kenneth Dickstein,
Lars Køber,
Milton Packer,
Jean L. Rouleau,
Simon Stewart,
Karl Swedberg,
Michael R. Zile,
Scott D. Solomon,
Pardeep Tags: Research Article Source Type: research
Impact of multimorbidity on mortality in HFrEF: Which comorbidities matter most? – An analysis of PARADIGM‐HF and ATMOSPHERE
ConclusionsIn HF, the impact of multimorbidity differed at the individual-patient and population level, depending on the prevalence of and the risk related to each comorbidity, and the interaction between individual comorbidities. Patients with co-existent PAD and stroke were at greatest individual risk whereas, from a population perspective, co-existent CKD and hypertension mattered mostThis article is protected by copyright. All rights reserved.
Source: European Journal of Heart Failure - April 17, 2023 Category: Cardiology Authors: Pooja Dewan,
Jo ão P Ferreira,
Jawad H Butt,
Mark C Petrie,
William T Abraham,
Akshay S. Desai,
Kenneth Dickstein,
Lars Køber,
Milton Packer,
Jean L Rouleau,
Simon Stewart,
Karl Swedberg,
Michael R Zile,
Scott D Solomon,
Pardeep S Jhund,
Tags: Research Article Source Type: research
Ventricular Stiffening and Chamber Contracture in Heart Failure with Higher Ejection Fraction
ConclusionMost pathophysiologic differences in patients with HFpEF and higher EF are related to smaller heart size, increased LV diastolic stiffness, and leftward shift in the EDPVR. These findings may help to explain the absence of efficacy for neurohormonal antagonists in this group and raise a new hypothesis, that interventions to stimulate eccentric LV remodeling and enhance diastolic capacitance may be beneficial for patients with HFpEF and EF in the higher range.
Source: European Journal of Heart Failure - March 30, 2023 Category: Cardiology Authors: Dejana Popovic,
Alessio Alogna,
Massar Omar,
Hidemi Sorimachi,
Kazunori Omote,
Yogesh N V Reddy,
Margaret M. Redfield,
Daniel Burkhoff,
Barry A Borlaug Tags: Research Article Source Type: research
Concomitant latent pulmonary vascular disease leads to impaired global cardiac performance in heart failure with preserved ejection fraction
ConclusionsLatent PVD is a feature of HFpEF and is associated with impaired RV functional reserve, global diastolic filling and LV-CI. This can be quantified by CMR and used to identify patients likely to benefit from IASD implantation.
Source: European Journal of Heart Failure - March 3, 2023 Category: Cardiology Authors: Andreas Schuster,
Alexander Schulz,
Torben Lange,
Ruben Evertz,
Finn Hartmann,
Johannes T. Kowallick,
Kristian Hellenkamp,
Martin Uecker,
Tim Seidler,
Gerd Hasenfu ß,
Sören J. Backhaus Tags: Research Article Source Type: research
Effects of haemodynamically atrio ‐ventricular optimized His bundle pacing on heart failure symptoms and exercise capacity: the His Optimized Pacing Evaluated for Heart Failure (HOPE‐HF) randomized, double‐blind, cross‐over trial
ConclusionHis bundle pacing did not increase peak oxygen uptake but, under double-blind conditions, significantly improved quality of life and was symptomatically preferred by the clear majority of patients. Ventricular pacing delivered via the His bundle did not adversely impact ventricular function during the 6 months.
Source: European Journal of Heart Failure - February 24, 2023 Category: Cardiology Authors: Zachary I. Whinnett,
Matthew J. Shun ‐Shin,
Mark Tanner,
Paul Foley,
Badri Chandrasekaran,
Philip Moore,
Shaumik Adhya,
Norman Qureshi,
Amal Muthumala,
Rebecca Lane,
Aldo Rinaldi,
Sharad Agarwal,
Francisco Leyva,
Jonathan Behar,
Sukh Bassi Tags: Research Article Source Type: research
Effect of Patisiran on Stroke Volume in Hereditary Transthyretin ‐Mediated Amyloidosis: Insights from Pressure‐Volume Analysis of the APOLLO Study
ConclusionsPatisiran may delay progression of LV chamber dysfunction starting at 9 months of therapy. These data elucidate the mechanisms by which transthyretin reducing therapies modulate progression of cardiac disease and need to be confirmed in ongoing phase III trials.
Source: European Journal of Heart Failure - January 25, 2023 Category: Cardiology Authors: Hannah R. Rosenblum,
Jan M. Griffin,
Masatoshi Minamisawa,
Narayana Prasad,
John Vest,
Matthew T. White,
Scott D. Solomon,
M.D. Daniel Burkhoff,
Mathew S. Maurer Tags: Research Article Source Type: research
Concomitant latent pulmonary vascular disease leads to impaired global cardiac performance in HFpEF
ConclusionsLatent PVD is a feature of HFpEF and is associated with impaired RV functional reserve, global diastolic filling and LV-CI. This can be quantified by CMR and used to identify patients likely to benefit from IASD implantation.
Source: European Journal of Heart Failure - January 24, 2023 Category: Cardiology Authors: Andreas Schuster,
Alexander Schulz,
Torben Lange,
Ruben Evertz,
Finn Hartmann,
Johannes T. Kowallick,
Kristian Hellenkamp,
Martin Uecker,
Tim Seidler,
Gerd Hasenfu ß,
Sören J. Backhaus Tags: Research Article Source Type: research
Normal and excessive muscle sympathetic nerve activity in heart failure: implications for future trials of therapeutic autonomic modulation
ConclusionBurst frequency and incidence exceeded normative values in only ~53% and ~33% of patients. Such diversity encourages selective deployment of sympatho-modulatory therapies. Clinical characteristics can highlight individuals who may benefit from future personalized interventions targeting pathological sympathetic activation.
Source: European Journal of Heart Failure - December 3, 2022 Category: Cardiology Authors: Mark B. Badrov,
Daniel A. Keir,
George Tomlinson,
Catherine F. Notarius,
Philip J. Millar,
Derek S. Kimmerly,
J. Kevin Shoemaker,
Evan Keys,
John S. Floras Tags: Research Article Source Type: research
Effects of haemodynamically atrio ‐ventricular optimized His‐pacing on heart failure symptoms and exercise capacity: The His Optimized Pacing Evaluated for Heart Failure (HOPE‐HF) randomised, double‐blind, cross‐over trial
ConclusionHis-bundle pacing did not increase peak oxygen uptake but, under double-blind conditions, significantly improved quality of life and was symptomatically preferred by the clear majority of patients. Ventricular pacing delivered via the His bundle did not adversely impact ventricular function during the 6 months.This article is protected by copyright. All rights reserved.
Source: European Journal of Heart Failure - November 21, 2022 Category: Cardiology Authors: Zachary I Whinnett,
Matthew J Shun ‐Shin,
Mark Tanner,
Paul Foley,
Badri Chandrasekaran,
Philip Moore,
Shaumik Adhya,
Norman Qureshi,
Amal Muthumala,
Rebecca Lane,
Aldo Rinaldi,
Sharad Agarwal,
Francisco Leyva,
Jonathan Behar,
Sukh Bassi, Tags: Research Article Source Type: research
The Effects of Mineralocorticoid Receptor Antagonists on Cardiovascular Outcomes in Patients With End ‐Stage Renal Disease and Heart Failure
ConclusionsIn patients undergoing regular dialysis who are diagnosed with heart failure, the use of MRAs is associated with lower risks of all-cause mortality and CV death. The benefits of MRA treatment in heart failure may persist in patients with ESRD. Further investigations through randomized controlled trials are needed to assess the efficacy and safety of MRAs in this high-risk population.This article is protected by copyright. All rights reserved.
Source: European Journal of Heart Failure - November 21, 2022 Category: Cardiology Authors: Donna Shu ‐Han Lin,
Fang‐Ju Irene Lin,
Yu‐Sheng Lin,
Jen‐Kuang Lee,
Yen‐Hung Lin Tags: Research Article Source Type: research
Dulaglutide and Cardiovascular and Heart Failure Outcomes in Patients With and Without Heart Failure: A Post ‐hoc Analysis from the REWIND Randomized Trial
ConclusionsDulaglutide was not associated with a reduction in HF events in patients with type 2 diabetes regardless of baseline HF status over 5.4 years of follow up.This article is protected by copyright. All rights reserved.
Source: European Journal of Heart Failure - September 8, 2022 Category: Cardiology Authors: Kelley R. H. Branch,
Gilles R. Dagenais,
Alvaro Avezum,
Jan Basile,
Ignacio Conget,
William C. Cushman,
Petr Jansky,
Mark Lakshmanan,
Fernando Lanas,
Lawrence A. Leiter,
Prem Pais,
Nana Pogosova,
Peter J. Raubenheimer,
Lars Ryden,
Jonathan E Tags: Research Article Source Type: research
Finerenone in patients with chronic kidney disease and type 2 diabetes with and without heart failure: a prespecified subgroup analysis of the FIDELIO ‐DKD trial
ConclusionIn FIDELIO-DKD, finerenone improved cardiorenal outcome in patients with CKD and T2D irrespective of baseline HF history.
Source: European Journal of Heart Failure - May 19, 2022 Category: Cardiology Authors: Gerasimos Filippatos,
Bertram Pitt,
Rajiv Agarwal,
Dimitrios Farmakis,
Luis M. Ruilope,
Peter Rossing,
Johann Bauersachs,
Robert J. Mentz,
Peter Kolkhof,
Charlie Scott,
Amer Joseph,
George L. Bakris,
Stefan D. Anker,
FIDELIO ‐DKD Investigat Tags: Research Article Source Type: research
