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Echocardiographic pressure –strain loop‐derived stroke work of the right ventricle: validation against the gold standard
ConclusionsIntegrated echo measurement of pressure –strain loop-derived SW correlates with PV loop-based assessment of RV SW. Wasted work correlates with invasive measures of load-independent RV function. Given the methodological and anatomical challenges of RV work assessment, evolution of this approach by incorporating more elaborated echo analy sis data and an RV reference curve might improve its reliability to mirror invasively assessed RV SW.
Source: ESC Heart Failure - July 7, 2023 Category: Cardiology Authors: Manuel J. Richter, Philipp Douschan, Federico Fortuni, Henning Gall, Hossein A. Ghofrani, Stanislav Keranov, Nils Kremer, Steffen D. Kriechbaum, Zvonimir A. Rako, Andreas J. Rieth, Bruno Brito Rocha, Werner Seeger, Daniel Zedler, Selin Yildiz Tags: Short Communication Source Type: research

Adrenomedullin peptides and precursor levels in relation to haemodynamics and prognosis after heart transplantation
ConclusionsElevated plasma levels of ADM may be a marker of pressure/volume overload in HF patients with PH, as well as long-term prognosis after HT. In line with previous studies, our findings additionally confirm that ADM may be a marker of venous congestion in HF. Further studies are encouraged to establish a deeper understanding of the properties of ADM and its relationship with HF and PH, in order to potentially facilitate clinical management of HF and associated PH.
Source: ESC Heart Failure - May 29, 2023 Category: Cardiology Authors: Abdulla Ahmed, Kriss Kania, Hebba Abdul Rahim, Salaheldin Ahmed, G öran Rådegran Tags: Original Article Source Type: research

Combination of SVI/S' and diagnostic scores for heart failure with preserved ejection fraction
This study aimed to compare the three approaches in patients with suspected HFpEF. Patients referred to right heart catheterization for suspected HFpEF were classified into low-, intermediate- and high-likelihood groups according to H2 FPEF or HFA-PEFF scores. A diagnosis of HFpEF was confirmed by pulmonary capillary wedge pressure (PCWP) of ≥15 mm Hg according to the guidelines. In result, a total of 128 patients were included. Of these, 71 patients with PCWP ≥15 mm Hg and 57 patients with PCWP <15 mm Hg. Moderate correlations were observed between H2 FPEF score, HFA-PEFF score, SVI/S' and PCWP. The area under curv...
Source: Clinical and Experimental Pharmacology and Physiology - May 19, 2023 Category: Drugs & Pharmacology Authors: Guanyu Mu Weiding Wang Changle Liu Juan Xie Hao Zhang Xiaowei Zhang Jingjin Che Gary Tse Tong Liu Guangping Li Huaying Fu Kangyin Chen Source Type: research

Bioimpedance based determination of cardiac index does not show enough trueness for point of care use in patients with systolic heart failure
AbstractCardiac output (CO) is a key parameter in diagnostics and therapy of heart failure (HF). The thermodilution method (TD) as gold standard for CO determination is an invasive procedure with corresponding risks. As an alternative, thoracic bioimpedance (TBI) has gained popularity for CO estimation as it is non-invasive. However, systolic heart failure (HF) itself might worsen its validity. The present study validated TBI against TD.  In patients with and without systolic HF (LVEF ≤ 50% or>  50% and NT-pro-BNP <  125 pg/ml, respectively) right heart catheterization including TD was performed. TBI (Ta...
Source: Journal of Clinical Monitoring and Computing - April 19, 2023 Category: Information Technology Source Type: research

Predictive Value of CHA2DS2-VASc Score in Patients with Contrast-Induced Nephropathy After Primary Percutaneous Coronary Intervention for ST-Elevated Myocardial Infarction
CONCLUSION: Our current study showed that the CHA2DS2-VASc risk score has an effective discriminating power in determining the contrast-induced nephropathy development and a score ≥2 defines the group at risk in patients presenting with ST-elevation myocardial infarction and underwent primary percutaneous coronary intervention. Moreover, contrast-induced nephropathy development is associated with longer coronary care unit stay and major adverse cardiac events (in-hospital decompensated heart failure, cardiogenic shock, cardiac arrest, and mortality).PMID:36916809 | DOI:10.5543/tkda.2022.46994
Source: Turk Kardiyoloji Dernegi arsivi - March 14, 2023 Category: Cardiology Authors: Esra D önmez Sevgi Özcan Orhan İnce İrfan Şahin Ertu ğrul Okuyan Source Type: research

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