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Multiple risk factors and ischaemic stroke in the elderly Asian population with and without atrial fibrillation. An analysis of 425,600 Chinese individuals without prior stroke.
In conclusion, an increasing cluster of multiple cardiovascular risk factors (besides AF) contributes to a greater risk for ischaemic stroke, especially in the elderly population. If elderly and with multiple risk factors, non-AF patients may have a risk of incident ischaemic stroke that is comparable or even higher than patients with AF, suggesting that the incremental stroke risk attributable to AF is marginal in such 'high risk' patients. PMID: 26322338 [PubMed - as supplied by publisher]
Source: Thrombosis and Haemostasis - August 31, 2015 Category: Hematology Authors: Guo Y, Wang H, Tian Y, Wang Y, Lip GY Tags: Thromb Haemost Source Type: research

Comparison of risk of serious cardiovascular events after haemorrhagic versus ischaemic stroke: a population-based study
CONCLUSIONS: The risk of subsequent cardiovascular events is similar between patients with incident haemorrhagic or ischaemic stroke. Patients with previous haemorrhagic stroke should be regarded as a population at very-high risk of subsequent CVD.PMID:35688459 | DOI:10.1055/a-1873-9092
Source: Thrombosis and Haemostasis - June 10, 2022 Category: Hematology Authors: Ralph Kwame Akyea Georgios Georgiopoulos Barbara Iyen Joe Kai Nadeem Qureshi George Ntaios Source Type: research

Essen Stroke Risk Score Predicts Clinical Outcomes in Heart Failure Patients With Preserved Ejection Fraction: Evidence From the TOPCAT trial
This study sought to determine whether the Essen Stroke Risk Score (ESRS) could predict the risks of adjudicated clinical outcomes in patients with Heart failure with preserved ejection fraction (HFpEF) from the TOPCAT trial. Of 3,441 HFpEF patients with a mean follow-up of 3.3 years, the risk of stroke ranged from 0.32% per year at an ESRS of 1-2 points to 1.71% per year at a score of ≥6 points. Each point increase in ESRS was associated with increased risks of stroke (HR=1.33 [95% CI 1.16-1.53]) with a C-index of 0.68, as well as myocardial infarction (HR=1.60 [95% CI 1.40-1.83]; C-index, 0.75), HF hospitalization (HR=...
Source: Thrombosis and Haemostasis - August 29, 2022 Category: Hematology Authors: Wengen Zhu Yalin Cao Min Ye Hulin Huang Yuzhong Wu Jianyong Ma Yugang Dong Xiao Liu Chen Liu Gregory Yh Lip Source Type: research

Relationship Between Red Cell Distribution Width and Stroke in Patients With Stable Chronic Heart Failure: A Propensity Score Matching Analysis
Conclusion: In conclusion, this study demonstrated that RDW may be important hematological indices for stroke in patients with HF using propensity score analysis.
Source: Clinical and Applied Thrombosis/Hemostasis - February 2, 2015 Category: Hematology Authors: Kaya, A., Isik, T., Kaya, Y., Enginyurt, O., Gunaydin, Z. Y., Iscanli, M. D., Kurt, M., Tanboga, I. H. Tags: Original Articles Source Type: research

Heart failure patients have enhanced cerebral autoregulation response in acute ischemic stroke
AbstractThe cerebrovascular effects of a failing heart-pump are largely unknown. Chronic heart failure (HF) might cause pre-conditioning effect on cerebral hemodynamics but not study so far in acute stroke. We aimed to investigate if HF induces effects in dynamic cerebral autoregulation (CA), within 6  h of symptom-onset through chronic stage of ischemic stroke. We enrolled 50 patients with acute ischemic stroke. Groups with (N = 8) and without HF and 20 heathy controls were compared. Arterial blood pressure (Finometer) and cerebral blood flow velocity (transcranial Doppler) were monitored w ithin 6 and at 24 h from ...
Source: Journal of Thrombosis and Thrombolysis - May 31, 2020 Category: Hematology Source Type: research

Association of education and feedback on hypertension management with risk for stroke and cardiovascular disease
CONCLUSIONS: This study does not support an association between education and feedback on hypertension management to primary care physicians and the risk for stroke or cardiovascular outcomes. The observed differences for mortality outcomes should be interpreted with caution.PMID:35179089 | DOI:10.1080/08037051.2022.2041393
Source: Blood Pressure - February 18, 2022 Category: Hematology Authors: Mattias Brunstr öm Nawi Ng John Dahlstr öm Lars H Lindholm Margareta Norberg Lennarth Nystr öm Lars Weinehall Bo Carlberg Source Type: research

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