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Source: Translational Stroke Research
Nutrition: Glucosamine
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Significance of Mitochondrial Protein Post-translational Modifications in Pathophysiology of Brain Injury
AbstractMitochondria are complex organelles that undergo constant fusion and fission in order to adapt to the ever-changing cellular environment. The fusion/fission proteins, localized in the inner and outer mitochondrial membrane, play critical roles under pathological conditions such as acute brain injury and neurodegenerative diseases. Post-translational modifications of these proteins tightly regulate their function and activity, ultimately impacting mitochondrial dynamics and their efficiency to generate ATP. The individual post-translational modifications that are known to affect mitochondrial dynamics include SUMOyl...
Source: Translational Stroke Research - September 21, 2017 Category: Neurology Source Type: research
