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Total 172 results found since Jan 2013.

Role of Renal Dysfunction as a Prognostic Factor in Acute Stroke Patients at a Tertiary Hospital in Northeastern Nigeria
Saudi J Kidney Dis Transpl. 2021 Jan-Feb;32(1):199-203. doi: 10.4103/1319-2442.318524.ABSTRACTChronic kidney disease (CKD) and stroke share many common risk factors, and the presence of CKD confers added risk factors for stroke. With increasing interest and understanding of the close relationship between the kidney and the brain, this study aims to assess the prevalence and impact of renal dysfunction on outcomes acute stroke patients. This is a prospective hospital-based study carried out in the neurology unit of University of Maiduguri Teaching Hospital, Maiduguri, northeastern Nigeria. The study population consisted of ...
Source: Saudi Journal of Kidney Diseases and Transplantation - June 19, 2021 Category: Urology & Nephrology Authors: Mohammad Maina Sulaiman Musa Mamman Watila Jummai Shettima Ibrahim Ummate Yakubu Wilberforce Nyandaiti Source Type: research

Gut microbes impact stroke severity via the trimethylamine N-oxide pathway
Cell Host Microbe. 2021 Jun 10:S1931-3128(21)00230-4. doi: 10.1016/j.chom.2021.05.002. Online ahead of print.ABSTRACTClinical studies have demonstrated associations between circulating levels of the gut-microbiota-derived metabolite trimethylamine-N-oxide (TMAO) and stroke incident risk. However, a causal role of gut microbes in stroke has not yet been demonstrated. Herein we show that gut microbes, through dietary choline and TMAO generation, directly impact cerebral infarct size and adverse outcomes following stroke. Fecal microbial transplantation from low- versus high-TMAO-producing human subjects into germ-free mice s...
Source: Cell Host and Microbe - June 17, 2021 Category: Microbiology Authors: Weifei Zhu Kymberleigh A Romano Lin Li Jennifer A Buffa Naseer Sangwan Prem Prakash Aaron N Tittle Xinmin S Li Xiaoming Fu Charlie Androjna Anthony J DiDonato Kimberly Brinson Bruce D Trapp Michael A Fischbach Federico E Rey Adeline M Hajjar Joseph A DiDo Source Type: research