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Heart Disease and Stroke Statistics-2022 Update: A Report From the American Heart Association
CONCLUSIONS: The Statistical Update represents a critical resource for the lay public, policymakers, media professionals, clinicians, health care administrators, researchers, health advocates, and others seeking the best available data on these factors and conditions.PMID:35078371 | DOI:10.1161/CIR.0000000000001052
Source: Atherosclerosis - January 26, 2022 Category: Cardiology Authors: Connie W Tsao Aaron W Aday Zaid I Almarzooq Alvaro Alonso Andrea Z Beaton Marcio S Bittencourt Amelia K Boehme Alfred E Buxton April P Carson Yvonne Commodore-Mensah Mitchell S V Elkind Kelly R Evenson Chete Eze-Nliam Jane F Ferguson Giuliano Generoso Jen Source Type: research

Heart Disease and Stroke Statistics-2023 Update: A Report From the American Heart Association
CONCLUSIONS: The Statistical Update represents a critical resource for the lay public, policymakers, media professionals, clinicians, health care administrators, researchers, health advocates, and others seeking the best available data on these factors and conditions.PMID:36695182 | DOI:10.1161/CIR.0000000000001123
Source: Atherosclerosis - January 25, 2023 Category: Cardiology Authors: Connie W Tsao Aaron W Aday Zaid I Almarzooq Cheryl A M Anderson Pankaj Arora Christy L Avery Carissa M Baker-Smith Andrea Z Beaton Amelia K Boehme Alfred E Buxton Yvonne Commodore-Mensah Mitchell S V Elkind Kelly R Evenson Chete Eze-Nliam Setri Fugar Giul Source Type: research

Exploring the Role of Irrational Beliefs, Lifestyle Behaviors, and Educational Status in 10-Year Cardiovascular Disease Risk: the ATTICA Epidemiological Study
CONCLUSIONS: The findings of this study underline the need to build new, holistic approaches in order to better understand the inter-relationships between irrational beliefs, lifestyle behaviors, social determinants, and CVD risk in individuals.PMID:35474416 | DOI:10.1007/s12529-022-10091-9
Source: Atherosclerosis - April 27, 2022 Category: Cardiology Authors: Christina Vassou Ekavi N Georgousopoulou Mary Yannakoulia Christina Chrysohoou Charalabos Papageorgiou Christos Pitsavos Mark Cropley Demosthenes B Panagiotakos Source Type: research

Long-term secondary prevention of cardiovascular disease with a Mediterranean diet and a low-fat diet (CORDIOPREV): a randomised controlled trial
This study is registered with ClinicalTrials.gov, NCT00924937.FINDINGS: From Oct 1, 2009, to Feb 28, 2012, a total of 1002 patients were enrolled, 500 (49·9%) in the low-fat diet group and 502 (50·1%) in the Mediterranean diet group. The mean age was 59·5 years (SD 8·7) and 827 (82·5%) of 1002 patients were men. The primary endpoint occurred in 198 participants: 87 in the Mediterranean diet group and 111 in the low-fat group (crude rate per 1000 person-years: 28·1 [95% CI 27·9-28·3] in the Mediterranean diet group vs 37·7 [37·5-37·9] in the low-fat group, log-rank p=0·039). Multivariable-adjusted hazard ratios ...
Source: Atherosclerosis - May 7, 2022 Category: Cardiology Authors: Javier Delgado-Lista Juan F Alcala-Diaz Jose D Torres-Pe ña Gracia M Quintana-Navarro Francisco Fuentes Antonio Garcia-Rios Ana M Ortiz-Morales Ana I Gonzalez-Requero Ana I Perez-Caballero Elena M Yubero-Serrano Oriol A Rangel-Zu ñiga Antonio Camargo Fe Source Type: research

Gut microbiota is a potential goalkeeper of dyslipidemia
Front Endocrinol (Lausanne). 2022 Sep 13;13:950826. doi: 10.3389/fendo.2022.950826. eCollection 2022.ABSTRACTDyslipidemia, as a common metabolic disease, could cause atherosclerosis, coronary heart disease, stroke and other cardio-cerebrovascular diseases. It is mainly caused by the interaction of genetic and environmental factors and its incidence has increased for several years. A large number of studies have shown that gut microbiota disorder is related to the development of dyslipidemia closely. Especially its metabolites such as short-chain fatty acids, bile acids and trimethylamine N-oxide affect dyslipidemia by regu...
Source: Atherosclerosis - September 30, 2022 Category: Cardiology Authors: Lirong Lei Ning Zhao Lei Zhang Jiamei Chen Xiaomin Liu Shenghua Piao Source Type: research

Influence of Management of Intensive Weight, Blood Pressure, and Lipids on Disease Severity in Patients with Carotid Atherosclerosis
CONCLUSIONS: A program for management of body weight, blood pressure, and blood lipids can effectively control the severity of carotid atherosclerosis, can prevent the disease's progression, and can be promoted as a clinical application.PMID:36455146
Source: Atherosclerosis - December 1, 2022 Category: Cardiology Authors: Yongjian Liu Xiaojing Yan Jin Zhou Litao Chen Zhixing Du Jianmin Pang Liya Jiao Dan Li Yongmin Deng Source Type: research

Research on Hepatocyte Regulation of PCSK9-LDLR and Its Related Drug Targets
Chin J Integr Med. 2023 Mar 13. doi: 10.1007/s11655-023-3545-z. Online ahead of print.ABSTRACTThe prevalence of hyperlipidemia has increased significantly due to genetic, dietary, nutritional and pharmacological factors, and has become one of the most common pathological conditions in humans. Hyperlipidemia can lead to a range of diseases such as atherosclerosis, stroke, coronary heart disease, myocardial infarction, diabetes, and kidney failure, etc. High circulating low-density lipoprotein cholesterol (LDL-C) is one of the causes of hyperlipidemia. LDL-C in the blood binds to LDL receptor (LDLR) and regulates cholesterol...
Source: Atherosclerosis - March 13, 2023 Category: Cardiology Authors: Su-Su Liu Tong Yu Yan-Fang Qiao Shu-Xiao Gu Xin-Lou Chai Source Type: research