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Specialty: Cytology
Procedure: Perfusion
Nutrition: Chloride
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Total 1 results found since Jan 2013.
GPR39 Knockout Worsens Microcirculatory Response to Experimental Stroke in a Sex-Dependent Manner
Transl Stroke Res. 2022 Oct 1. doi: 10.1007/s12975-022-01093-6. Online ahead of print.ABSTRACTNo current treatments target microvascular reperfusion after stroke, which can contribute to poor outcomes even after successful clot retrieval. The G protein-coupled receptor GPR39 is expressed in brain peri-capillary pericytes, and has been implicated in microvascular regulation, but its role in stroke is unknown. We tested the hypothesis that GPR39 plays a protective role after stroke, in part due to preservation of microvascular perfusion. We generated GPR39 knockout (KO) mice and tested whether GPR39 gene deletion worsens cap...
Source: Cell Research - October 1, 2022 Category: Cytology Authors: Yifan Xu Wenri H Zhang Elyse M Allen Lev M Fedorov Anthony P Barnes Zu Yuan Qian Thierno Madjou Bah Yuandong Li Ruikang K Wang Robert E Shangraw Nabil J Alkayed Source Type: research
