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Total 326 results found since Jan 2013.

Barriers and facilitators to staying in work after stroke: insight from an online forum
Conclusions Despite having been able to return to work after a stroke, people may still experience difficulties in staying in work and risking losing their job. There is a need to improve awareness, in particular of invisible stroke-related impairments, among stroke survivors, work personnel and clinicians. This might be achieved through improved assessments of residual impairments in the workplace and in general practice. Future studies should investigate the effect of unrecognised fatigue and invisible impairments on staying in work following stroke, and explore the potential role for primary care in supporting stroke su...
Source: BMJ Open - April 5, 2016 Category: Journals (General) Authors: Balasooriya-Smeekens, C., Bateman, A., Mant, J., De Simoni, A. Tags: Open access, Cardiovascular medicine, General practice / Family practice, Occupational and environmental medicine, Qualitative research, Rehabilitation medicine, Research methods Source Type: research

Are healthcare costs from obesity associated with body mass index, comorbidity or depression? Cohort study using electronic health records
The objective of this study was to evaluate the association between body mass index (BMI) and healthcare costs in relation to obesity‐related comorbidity and depression. A population‐based cohort study was undertaken in the UK Clinical Practice Research Datalink (CPRD). A stratified random sample was taken of participants registered with general practices in England in 2008 and 2013. Person time was classified by BMI category and morbidity status using first diagnosis of diabetes (T2DM), coronary heart disease (CHD), stroke or malignant neoplasms. Participants were classified annually as depressed or not depressed. Cos...
Source: Clinical Obesity - March 31, 2016 Category: Eating Disorders and Weight Management Authors: C. Rudisill, J. Charlton, H. P. Booth, M. C. Gulliford Tags: Original Article Source Type: research

Prevalence of chronic diseases among older patients in German general practices.
CONCLUSIONS: Our study showed that the prevalence of CDs is high in the German elderly population. Hypertension was the most frequent chronic condition and around 25% of patients displayed at least four CDs. PMID: 26977142 [PubMed - in process]
Source: GMS German Medical Science - March 17, 2016 Category: Journals (General) Tags: Ger Med Sci Source Type: research

Use of forms for follow-up of diabetes in general practice.
Abstract BACKGROUND The majority of patients with type 2 diabetes are followed up in general practice. We have investigated whether the use of forms by GPs for recording clinical data contributes to lower mortality and morbidity for this patient group.MATERIAL AND METHOD This systematic review is based on literature searches in MEDLINE, EMBASE, ISI Web of Science, Cochrane CENTRAL and PubMed. We included studies that 1) dealt with adults over 18 years of age with diabetes who were followed up in the primary health service and 2) compared mortality and morbidity with and without the use of forms. We summarised the ...
Source: Tidsskrift for den Norske Laegeforening - March 1, 2016 Category: Journals (General) Authors: Larun L, Bjørner T, Fretheim A, Brurberg KG Tags: Tidsskr Nor Laegeforen Source Type: research

Can CREST Procedural Results Be Reproduced in General Practice in Post CREST Era? Analysis of National Surgical Quality Improvement Program (NSQIP) Registry (S42.001)
Conclusions: Our results support reproducibility of CREST procedural outcomes for both CEA and CAS in general practice in post-trial period.Disclosure: Dr. Jani has nothing to disclose. Dr. Zafar has nothing to disclose. Dr. Afzal has nothing to disclose. Dr. Qureshi has nothing to disclose.
Source: Neurology - February 7, 2016 Category: Neurology Authors: Jani, V., Zafar, A., Afzal, M., Qureshi, A. Tags: Stroke Mechanism and Modifiers Source Type: research

Stroke prevention in atrial fibrillation: we can do better.
PMID: 26823244 [PubMed - in process]
Source: The British Journal of General Practice - January 30, 2016 Category: Primary Care Authors: Kearney M, Fay M, Fitzmaurice DA Tags: Br J Gen Pract Source Type: research

Low to moderate quality evidence demonstrates the potential benefits and adverse events of cannabinoids for certain medical indications
Commentary on: Whiting PF, Wolff RF, Deshpande S, et al.. Cannabinoids for medical use: a systematic review and meta-analysis. JAMA 2015;313:2456–73. Context As of September 2015, 23 states and the District of Columbia in the USA legalised the medicinal use of marijuana, underscoring the need for physicians to understand the science underlying medical marijuana as well as the practical issues associated with it. For years policymakers, scientists and physicians alike have debated the potential risks associated with marijuana use.1 Now marijuana's utility as a treatment for certain medical indications has taken focus....
Source: Evidence-Based Medicine - January 22, 2016 Category: Internal Medicine Authors: Hill, K. P., Hurley-Welljams-Dorof, W. M. Tags: Sexual transmitted infections (viral), Clinical trials (epidemiology), General practice / family medicine, Genetics, Immunology (including allergy), HIV/AIDS, Drugs: CNS (not psychiatric), Pain (neurology), Sleep disorders (neurology), Stroke, Ophthalmolo Source Type: research

General practice based psychosocial interventions for supporting carers of people with dementia or stroke: a systematic review
Particularly with ageing populations, dementia and stroke and their resultant disability are worldwide concerns. Much of the support for people with these conditions comes from unpaid carers or caregivers. The...
Source: BMC Family Practice - January 15, 2016 Category: Primary Care Authors: Nan Greenwood, Ferruccio Pelone and Anne-Marie Hassenkamp Source Type: research

Oxidative phosphorylation and lacunar stroke: Genome-wide enrichment analysis of common variants
Conclusions: Our results implicate the OXPHOS pathway in the pathogenesis of lacunar stroke, and show the association is specific to patients with the MLI/LA subtype. They show that MRI-based subtyping of lacunar stroke can provide insights into disease pathophysiology, and imply that different radiologic subtypes of lacunar stroke subtypes have distinct underlying pathophysiologic processes.
Source: Neurology - January 11, 2016 Category: Neurology Authors: Traylor, M., Anderson, C. D., Hurford, R., Bevan, S., Markus, H. S. Tags: MRI, All Cerebrovascular disease/Stroke, Case control studies, Association studies in genetics ARTICLE Source Type: research

Understanding stroke survivors and informal carers experiences of and need for primary care and community health services--a systematic review of the qualitative literature: protocol
Introduction Despite the rising prevalence of stroke, no comprehensive model of postacute stroke care exists. Research on stroke has focused on acute care and early supported discharge, with less attention dedicated to longer term support in the community. Likewise, relatively little research has focused on long-term support for informal carers. This review aims to synthesise and appraise extant qualitative evidence on: (1) long-term healthcare needs of stroke survivors and informal carers, and (2) their experiences of primary care and community health services. The review will inform the development of a primary care mode...
Source: BMJ Open - January 6, 2016 Category: Journals (General) Authors: Aziz, N. A., Pindus, D. M., Mullis, R., Walter, F. M., Mant, J., Lim, Rundell, Hobbs Tags: Open access, General practice / Family practice, Qualitative research, Research methods Protocol Source Type: research

HbA1c measurement and relationship to incident stroke
ConclusionsThe frequency of diabetes testing was higher in patients who had experienced a stroke before and after their incident stroke compared with control patients but did not increase after their stroke. Glucose control improved significantly in the year after a stroke.This article is protected by copyright. All rights reserved.
Source: Diabetic Medicine - December 19, 2015 Category: Endocrinology Authors: R. Robson, A. Lacey, S. Luzio, H Van Woerden, M. Heaven, M. Wani, J. Halcox, L. Castilla‐Guerra, J. Dawson, J. Hewitt Tags: Short Report Source Type: research

Implementing guidelines to routinely prevent chronic vascular disease in primary care: the Preventive Evidence into Practice cluster randomised controlled trial
Conclusions This intervention was associated with improved recording of some risk factors but no change in the level of risk at the follow-up audit. Trial registration number Australian and New Zealand Clinical Trials Register (ANZCTR): ACTRN12612000578808, results.
Source: BMJ Open - December 11, 2015 Category: Journals (General) Authors: Harris, M. F., Parker, S. M., Litt, J., van Driel, M., Russell, G., Mazza, D., Jayasinghe, U. W., Del Mar, C., Lloyd, J., Smith, J., Zwar, N., Taylor, R., Powell Davies, G., On behalf of the Preventive Evidence into Practice (PEP) Partnership Group, On be Tags: Open access, Cardiovascular medicine, Evidence based practice, General practice / Family practice, Health services research, Public health, Diabetes and Endocrinology Source Type: research

Evaluating quality and its determinants in lipid control for secondary prevention of heart disease and stroke in primary care: a study in an inner London Borough
Conclusions In this study, the key factor that explained poor lipid control in people with CVD was having no current prescription record of a statin. Women were more likely to have poorly controlled cholesterol (independent of comorbid risk factors and after adjusting for age, ethnicity, deprivation index and practice-level variation). Women with CVD should be offered statin prescription and may require higher statin dosage for improved control.
Source: BMJ Open - December 9, 2015 Category: Journals (General) Authors: Dodhia, H., Kun, L., Logan Ellis, H., Crompton, J., Wierzbicki, A. S., Williams, H., Hodgkinson, A., Balazs, J. Tags: Open access, Cardiovascular medicine, General practice / Family practice, Health services research Source Type: research

Primary Care Atrial Fibrillation Service: outcomes from consultant-led anticoagulation assessment clinics in the primary care setting in the UK
Conclusions Systematic identification of patients with AF with high stroke-risk and consultation in PCAF consultant-led clinics effectively delivers oral anticoagulation to high-risk patients with AF in the community.
Source: BMJ Open - December 9, 2015 Category: Journals (General) Authors: Das, M., Panter, L., Wynn, G. J., Taylor, R. M., Connor, N., Mills, J. D., Kirchhof, P., Gupta, D. Tags: Open access, Cardiovascular medicine, General practice / Family practice, Pharmacology and therapeutics Research Source Type: research

New oral anticoagulants for nonvalvular atrial fibrillation in the elderly: Limited applicability in primary care.
CONCLUSION: There is uncertainty about effectiveness and safety of NOACs in unselected elderly patients with AF in primary care. Therefore, the balance between benefit and harm is still unclear. For this reason, routine use of NOACs is not recommended in elderly patients in primary care. PMID: 25495417 [PubMed - in process]
Source: European Journal of General Practice - December 4, 2015 Category: Primary Care Tags: Eur J Gen Pract Source Type: research