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Neuropharmacologic Approaches to Restore the Brain’s Microenvironment
Abstract Maintaining the central nervous system microenvironment after injury, infection, inflammatory and degenerative diseases is contingent upon adequate control of glial homeostatic functions. Disease is caused by microbial, environmental and endogenous factors that compromise ongoing nervous system functions. The final result is neuronal injury, dropout and nerve connection loss, and these underlie the pathobiology of Alzheimer’s and Parkinson’s disease, amyotrophic lateral sclerosis, stroke, and bacterial, parasitic and viral infections. However, what promotes disease are homeostatic changes in the brain...
Source: Journal of NeuroImmune Pharmacology - June 27, 2016 Category: Drugs & Pharmacology Source Type: research

Neuropharmacologic Approaches to Restore the Brain ’s Microenvironment
Abstract Maintaining the central nervous system microenvironment after injury, infection, inflammatory and degenerative diseases is contingent upon adequate control of glial homeostatic functions. Disease is caused by microbial, environmental and endogenous factors that compromise ongoing nervous system functions. The final result is neuronal injury, dropout and nerve connection loss, and these underlie the pathobiology of Alzheimer ’s and Parkinson’s disease, amyotrophic lateral sclerosis, stroke, and bacterial, parasitic and viral infections. However, what promotes disease are homeostatic changes in the brain’s mi...
Source: Journal of NeuroImmune Pharmacology - June 27, 2016 Category: Drugs & Pharmacology Source Type: research