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Zika associated Guillain-Barre syndrome in the United States (P2.327)
Conclusions:Zika can induce GBS after a brief viral illness. Neuropathy can be a mixture of demyelinating and axonal. Dysautonomia may also be present including severe dysphagia, orthostatics and retention.Zika RNA has a short detection window in serum and CSF making a diagnosis time sensitive. Serological assays using IgM and IgG cross-react with other flaviviruses making them unable to differentiate between recent Zika exposure and cross reactivity with Dengue and Chikungunya. Our pt likely had prior exposure to Dengue, being from an endemic area. Prior Dengue exposure may possibly modulate the response to Zika via antib...
Source: Neurology - April 17, 2017 Category: Neurology Authors: Tantillo, G., Sclar, G., Vasa, C., Shin, S., Sivak, M. Tags: Zika, Chikungunya, West Nile Virus, and Other Viral Infections I Source Type: research

Neurological involvement in Chikangunya Virus infection (S40.007)
Conclusions:Chikangunya fever is frequently associated with neurological symptoms, especially alteration in sensorium, neutrophilia and hyponatremia in more than two-thirds of the patients, sepsis and hepatorenal dysfunction in almost one third of the patients, CSF lymphocytosis with raised proteins and topographically involves temporal and frontal lobes predominantly.Disclosure: Dr. Anand has nothing to disclose. Dr. Kasundra has nothing to disclose. Dr. Prasad has nothing to disclose. Dr. Handa has nothing to disclose.
Source: Neurology - April 17, 2017 Category: Neurology Authors: Anand, R., Kasundra, G., Prasad, A., Handa, R. Tags: Infectious Disease: The Neurology of Zika, Chikungunya, and Acute Flaccid Myelitis Source Type: research