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Characterization of an Enterococcus faecalis Bacteriophage vB_EfaM_LG1 and Its Synergistic Effect With Antibiotic
Enterococcus faecalis is a Gram-positive opportunistic pathogen that could cause pneumonia and bacteremia in stroke patients. The development of antibiotic resistance in hospital-associated E. faecalis is a formidable public health threat. Bacteriophage therapy is a renewed solution to treat antibiotic-resistant bacterial infections. However, bacteria can acquire phage resistance quite quickly, which is a significant barrier to phage therapy. Here, we characterized a lytic E. faecalis bacteriophage Vb_EfaM_LG1 with lytic activity. Its genome did not contain antibiotic resistance or virulence genes. Vb_EfaM_LG1 effectively ...
Source: Frontiers in cellular and infection microbiology - July 16, 2021 Category: Microbiology Source Type: research

Emphysematous cystitis: An atypical multi-organism presentation.
Abstract An 84-year-old diabetic women receiving in-hospital stroke management began suffering from vague lower abdominal pain, increased urge incontinence and gross hematuria. Physical examination revealed suprapubic tenderness and a tympanic bladder. A computed tomography confirmed a distended bladder with gas foci delineating the bladder wall. Microbiology revealed an atypical multi-organism presentation of Klebsiella pneumoniae and Enterococcus species. Emphysematous cystitis is characterized by air within the bladder wall often found in elderly diabetic females. Predominant organisms include Escherichia coli ...
Source: Canadian Urological Association Journal - March 1, 2014 Category: Urology & Nephrology Authors: Bos D, Patal P, Ditullio S Tags: Can Urol Assoc J Source Type: research