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Case Report: Dengue Hemorrhagic Fever with Ischemic Stroke
We report a case of ischemic stroke in a patient with dengue hemorrhagic fever. A 52-year-old previously healthy male presented with a history of fever for 2 days, and left-sided weakness and numbness of sudden onset. MRI scanning showed a right-sided thalamic lacunar infarct. Diagnosis of dengue fever was made based on leuco-thrombocytopenia, positive dengue nonstructural protein-1 (NS-1) antigen, and positive dengue IgM antibodies. Severity of limb weakness correlated with the critical phase of dengue hemorrhagic fever (DHF). He was discharged home with good recovery from neurological symptoms and disability. Strokes are...
Source: The American Journal of Tropical Medicine and Hygiene - November 15, 2021 Category: Tropical Medicine Authors: B W M K E Basnayake K G S K Somaratne C U Goonetilleke P M Y I Tilakaratna U K Ranawaka Source Type: research

Zika Virus Emergence and Expansion: Lessons Learned from Dengue and Chikungunya May Not Provide All the Answers.
Abstract Following the emergence of Zika in the past decade, there are lessons to be learned from similar emergence events of dengue (DENV) and chikungunya (CHIKV). Specifically, as Zika emerges in the Americas there is a natural tendency to apply the knowledge base of DENV and CHIKV to mitigation and control of a virus with such a similar transmission system. However, there are marked differences that may preclude such broad stroke application of this knowledge base without making potentially faulty assumptions. Herein, Zika virus (ZIKV) transmission is reviewed, and the commonalities among these three arboviruse...
Source: The American Journal of Tropical Medicine and Hygiene - February 22, 2016 Category: Tropical Medicine Authors: Christofferson RC Tags: Am J Trop Med Hyg Source Type: research

A Population-Based Cohort Study on Chronic Comorbidity Risk Factors for Adverse Dengue Outcomes
Am J Trop Med Hyg. 2021 Sep 27:tpmd210716. doi: 10.4269/ajtmh.21-0716. Online ahead of print.ABSTRACTThe global burden of dengue is increasing against a background of rising global prevalence of chronic noncommunicable diseases (NCDs) and an epidemiological shift of dengue toward older age groups. The contribution of NCDs toward risk for adverse clinical and healthcare utilization outcomes was assessed in a national linked-database study. About 51,433 adult dengue cases between 2014 and 2015 were assessed for outpatient and inpatient claims data in Taiwan's National Health Insurance Research Database for the 30 days after ...
Source: The American Journal of Tropical Medicine and Hygiene - September 28, 2021 Category: Tropical Medicine Authors: Chia-En Lien Yiing-Jenq Chou Yi-Jung Shen Theodore Tsai Nicole Huang Source Type: research