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Source: Journal of Medicine and Life
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Total 306 results found since Jan 2013.
Diagnosis and treatment of Watershed strokes: a narrative review
J Med Life. 2023 Jun;16(6):842-850. doi: 10.25122/jml-2023-0127.ABSTRACTWatershed strokes have been described previously as ischemic strokes located in vulnerable border zones between brain tissue supplied by the anterior, posterior, and middle cerebral arteries in the distal junction between two non-anastomotic arterial territories. Ischemic strokes in border zones are well-recognized entities and well-described in terms of imaging features, but the pathophysiological mechanism of brain injury production is not fully defined. Border zone ischemia is caused by cerebral hypoperfusion through decreased cerebral blood flow an...
Source: Journal of Medicine and Life - September 7, 2023 Category: General Medicine Authors: Oana Andreea Dogariu Ioan Dogariu Corina Maria Vasile Mihaela Corina Berceanu Victor Cornel Raicea Carmen Valeria Albu Ioana Andreea Gheonea Source Type: research
Role of Iberin as an anti-apoptotic agent on renal ischemia-reperfusion injury in rats
This study aimed to investigate the therapeutic potential of Iberin, known for its anti-inflammatory, antioxidant, and antiapoptotic properties, in a rat model of renal IRI. Twenty-four adult male rats were randomly divided into four groups: Group I (Sham group) underwent laparotomy without IRI induction; Group II (Control group) underwent laparotomy followed by renal artery clamping for 30 minutes to induce ischemia, followed by 2 hours of reperfusion; Group III (Iberin treatment group) received a pre-injection of Iberin (15 mg/kg) and underwent 30 minutes of ischemia followed by 2 hours of reperfusion; and Group IV (Vehi...
Source: Journal of Medicine and Life - September 7, 2023 Category: General Medicine Authors: Yahiya Ibrahim Yahiya Najah Rayish Hadi Ahmed Abu Raghif Heider Qassam Noor Ghaffar Said Al Habooby Source Type: research
Diagnosis and treatment of Watershed strokes: a narrative review
J Med Life. 2023 Jun;16(6):842-850. doi: 10.25122/jml-2023-0127.ABSTRACTWatershed strokes have been described previously as ischemic strokes located in vulnerable border zones between brain tissue supplied by the anterior, posterior, and middle cerebral arteries in the distal junction between two non-anastomotic arterial territories. Ischemic strokes in border zones are well-recognized entities and well-described in terms of imaging features, but the pathophysiological mechanism of brain injury production is not fully defined. Border zone ischemia is caused by cerebral hypoperfusion through decreased cerebral blood flow an...
Source: Journal of Medicine and Life - September 7, 2023 Category: General Medicine Authors: Oana Andreea Dogariu Ioan Dogariu Corina Maria Vasile Mihaela Corina Berceanu Victor Cornel Raicea Carmen Valeria Albu Ioana Andreea Gheonea Source Type: research
Serum biomarkers to predict hemorrhagic transformation and ischemic stroke outcomes in a prospective cohort study
This study aimed to investigate the potential prognosis role of non-specific laboratory data at admission and baseline MMP-2 and MMP-9 serum levels in predicting HT risk, discharge, and 3-month follow-up status of IS patients. Data from 150 successive acute cerebral infarction patients were analyzed in a prospective cohort study. The active group included patients who developed HT during hospitalization (55 persons). There were no significant differences in age, gender distribution, time to admission, or time to blood sample collection for MMPs measurement between patients in the active and control groups. IS patients from...
Source: Journal of Medicine and Life - September 7, 2023 Category: General Medicine Authors: Elena Costru-Tasnic Mihail Gavriliuc Elena Manole Source Type: research
Role of Iberin as an anti-apoptotic agent on renal ischemia-reperfusion injury in rats
This study aimed to investigate the therapeutic potential of Iberin, known for its anti-inflammatory, antioxidant, and antiapoptotic properties, in a rat model of renal IRI. Twenty-four adult male rats were randomly divided into four groups: Group I (Sham group) underwent laparotomy without IRI induction; Group II (Control group) underwent laparotomy followed by renal artery clamping for 30 minutes to induce ischemia, followed by 2 hours of reperfusion; Group III (Iberin treatment group) received a pre-injection of Iberin (15 mg/kg) and underwent 30 minutes of ischemia followed by 2 hours of reperfusion; and Group IV (Vehi...
Source: Journal of Medicine and Life - September 7, 2023 Category: General Medicine Authors: Yahiya Ibrahim Yahiya Najah Rayish Hadi Ahmed Abu Raghif Heider Qassam Noor Ghaffar Said Al Habooby Source Type: research
Diagnosis and treatment of Watershed strokes: a narrative review
J Med Life. 2023 Jun;16(6):842-850. doi: 10.25122/jml-2023-0127.ABSTRACTWatershed strokes have been described previously as ischemic strokes located in vulnerable border zones between brain tissue supplied by the anterior, posterior, and middle cerebral arteries in the distal junction between two non-anastomotic arterial territories. Ischemic strokes in border zones are well-recognized entities and well-described in terms of imaging features, but the pathophysiological mechanism of brain injury production is not fully defined. Border zone ischemia is caused by cerebral hypoperfusion through decreased cerebral blood flow an...
Source: Journal of Medicine and Life - September 7, 2023 Category: General Medicine Authors: Oana Andreea Dogariu Ioan Dogariu Corina Maria Vasile Mihaela Corina Berceanu Victor Cornel Raicea Carmen Valeria Albu Ioana Andreea Gheonea Source Type: research
Serum biomarkers to predict hemorrhagic transformation and ischemic stroke outcomes in a prospective cohort study
This study aimed to investigate the potential prognosis role of non-specific laboratory data at admission and baseline MMP-2 and MMP-9 serum levels in predicting HT risk, discharge, and 3-month follow-up status of IS patients. Data from 150 successive acute cerebral infarction patients were analyzed in a prospective cohort study. The active group included patients who developed HT during hospitalization (55 persons). There were no significant differences in age, gender distribution, time to admission, or time to blood sample collection for MMPs measurement between patients in the active and control groups. IS patients from...
Source: Journal of Medicine and Life - September 7, 2023 Category: General Medicine Authors: Elena Costru-Tasnic Mihail Gavriliuc Elena Manole Source Type: research
Role of Iberin as an anti-apoptotic agent on renal ischemia-reperfusion injury in rats
This study aimed to investigate the therapeutic potential of Iberin, known for its anti-inflammatory, antioxidant, and antiapoptotic properties, in a rat model of renal IRI. Twenty-four adult male rats were randomly divided into four groups: Group I (Sham group) underwent laparotomy without IRI induction; Group II (Control group) underwent laparotomy followed by renal artery clamping for 30 minutes to induce ischemia, followed by 2 hours of reperfusion; Group III (Iberin treatment group) received a pre-injection of Iberin (15 mg/kg) and underwent 30 minutes of ischemia followed by 2 hours of reperfusion; and Group IV (Vehi...
Source: Journal of Medicine and Life - September 7, 2023 Category: General Medicine Authors: Yahiya Ibrahim Yahiya Najah Rayish Hadi Ahmed Abu Raghif Heider Qassam Noor Ghaffar Said Al Habooby Source Type: research
Diagnosis and treatment of Watershed strokes: a narrative review
J Med Life. 2023 Jun;16(6):842-850. doi: 10.25122/jml-2023-0127.ABSTRACTWatershed strokes have been described previously as ischemic strokes located in vulnerable border zones between brain tissue supplied by the anterior, posterior, and middle cerebral arteries in the distal junction between two non-anastomotic arterial territories. Ischemic strokes in border zones are well-recognized entities and well-described in terms of imaging features, but the pathophysiological mechanism of brain injury production is not fully defined. Border zone ischemia is caused by cerebral hypoperfusion through decreased cerebral blood flow an...
Source: Journal of Medicine and Life - September 7, 2023 Category: General Medicine Authors: Oana Andreea Dogariu Ioan Dogariu Corina Maria Vasile Mihaela Corina Berceanu Victor Cornel Raicea Carmen Valeria Albu Ioana Andreea Gheonea Source Type: research
Role of Iberin as an anti-apoptotic agent on renal ischemia-reperfusion injury in rats
This study aimed to investigate the therapeutic potential of Iberin, known for its anti-inflammatory, antioxidant, and antiapoptotic properties, in a rat model of renal IRI. Twenty-four adult male rats were randomly divided into four groups: Group I (Sham group) underwent laparotomy without IRI induction; Group II (Control group) underwent laparotomy followed by renal artery clamping for 30 minutes to induce ischemia, followed by 2 hours of reperfusion; Group III (Iberin treatment group) received a pre-injection of Iberin (15 mg/kg) and underwent 30 minutes of ischemia followed by 2 hours of reperfusion; and Group IV (Vehi...
Source: Journal of Medicine and Life - September 7, 2023 Category: General Medicine Authors: Yahiya Ibrahim Yahiya Najah Rayish Hadi Ahmed Abu Raghif Heider Qassam Noor Ghaffar Said Al Habooby Source Type: research
Diagnosis and treatment of Watershed strokes: a narrative review
J Med Life. 2023 Jun;16(6):842-850. doi: 10.25122/jml-2023-0127.ABSTRACTWatershed strokes have been described previously as ischemic strokes located in vulnerable border zones between brain tissue supplied by the anterior, posterior, and middle cerebral arteries in the distal junction between two non-anastomotic arterial territories. Ischemic strokes in border zones are well-recognized entities and well-described in terms of imaging features, but the pathophysiological mechanism of brain injury production is not fully defined. Border zone ischemia is caused by cerebral hypoperfusion through decreased cerebral blood flow an...
Source: Journal of Medicine and Life - September 7, 2023 Category: General Medicine Authors: Oana Andreea Dogariu Ioan Dogariu Corina Maria Vasile Mihaela Corina Berceanu Victor Cornel Raicea Carmen Valeria Albu Ioana Andreea Gheonea Source Type: research
Serum biomarkers to predict hemorrhagic transformation and ischemic stroke outcomes in a prospective cohort study
This study aimed to investigate the potential prognosis role of non-specific laboratory data at admission and baseline MMP-2 and MMP-9 serum levels in predicting HT risk, discharge, and 3-month follow-up status of IS patients. Data from 150 successive acute cerebral infarction patients were analyzed in a prospective cohort study. The active group included patients who developed HT during hospitalization (55 persons). There were no significant differences in age, gender distribution, time to admission, or time to blood sample collection for MMPs measurement between patients in the active and control groups. IS patients from...
Source: Journal of Medicine and Life - September 7, 2023 Category: General Medicine Authors: Elena Costru-Tasnic Mihail Gavriliuc Elena Manole Source Type: research
Role of Iberin as an anti-apoptotic agent on renal ischemia-reperfusion injury in rats
This study aimed to investigate the therapeutic potential of Iberin, known for its anti-inflammatory, antioxidant, and antiapoptotic properties, in a rat model of renal IRI. Twenty-four adult male rats were randomly divided into four groups: Group I (Sham group) underwent laparotomy without IRI induction; Group II (Control group) underwent laparotomy followed by renal artery clamping for 30 minutes to induce ischemia, followed by 2 hours of reperfusion; Group III (Iberin treatment group) received a pre-injection of Iberin (15 mg/kg) and underwent 30 minutes of ischemia followed by 2 hours of reperfusion; and Group IV (Vehi...
Source: Journal of Medicine and Life - September 7, 2023 Category: General Medicine Authors: Yahiya Ibrahim Yahiya Najah Rayish Hadi Ahmed Abu Raghif Heider Qassam Noor Ghaffar Said Al Habooby Source Type: research
