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Effects of cerebral small vessel disease on the outcome of patients with ischemic stroke caused by large artery atherosclerosis.
DISCUSSION: CSVD can significantly influence the clinical outcome of stroke in patients with cerebral infarction caused by LAA, and the methods to capture whole brain CSVD burden cross the spectrum of changes in CSVD imaging features may be useful for patient stratification in clinical trials. Further studies should be performed to validate the relationship between CSVD related brain damage and LAA stroke. PMID: 29543130 [PubMed - as supplied by publisher]
Source: Neurological Research - March 20, 2018 Category: Neurology Tags: Neurol Res Source Type: research

Frequency and risk factors of spontaneous hemorrhagic transformation following ischemic stroke on the initial brain CT or MRI: data from the China National Stroke Registry (CNSR).
DISCUSSION: Spontaneous HT occurred in 0.92% of the patients with IS in the acute stage. Being female, excess alcohol consumption, atrial fibrillation, and a prolonged period between IS onset and initial imaging were associated with an increased risk of spontaneous HT. PMID: 27320249 [PubMed - in process]
Source: Neurological Research - June 21, 2016 Category: Neurology Tags: Neurol Res Source Type: research

Reversed ophthalmic artery flow following ischemic stroke: a possible predictor of outcomes following carotid artery stenting.
This study provides evidence that CAS is a valid and effective treatment option regardless of whether patients exhibited ROAF or not. Patients without ROAF were significantly more likely to have improved mid-term functional outcomes compared to those with ROAF. In the group without ROAF admission, CRP may play a role in predicting subsequent functional outcomes, whereas admission Barthel Index was a predictor of outcome in the ROAF group. PMID: 30433861 [PubMed - as supplied by publisher]
Source: Neurological Research - November 17, 2018 Category: Neurology Tags: Neurol Res Source Type: research

Thrombolysis with rhPro-UK 3 to 6 hours after embolic stroke in rat.
Conclusions: RhPro-UK had an obvious therapeutic effect on ischemic stroke caused by thrombosis, and could be started within 4.5 h TTW with less side effects of cerebral hemorrhage than that of UK. PMID: 31584350 [PubMed - as supplied by publisher]
Source: Neurological Research - October 5, 2019 Category: Neurology Tags: Neurol Res Source Type: research

S100β as a biomarker for differential diagnosis of intracerebral hemorrhage and ischemic stroke.
CONCLUSION: S100β could serve as a potential biomarker for differentiating between ICH and IS and predicting short-term functional outcome after ICH. PMID: 27078704 [PubMed - as supplied by publisher]
Source: Neurological Research - April 16, 2016 Category: Neurology Tags: Neurol Res Source Type: research

The relationship between the platelet to leukocyte ratio and mechanical thrombectomy outcomes in acute ischemic stroke patients.
CONCLUSION: Platelet to leukocyte ratio may be use to assess the risk of functional outcome and sICH in patients with acute anterior circulation occlusion stroke undergoing endovascular treatment in real world China. PMID: 32643590 [PubMed - as supplied by publisher]
Source: Neurological Research - July 11, 2020 Category: Neurology Tags: Neurol Res Source Type: research

The association between White matter microstructure alterations detected by Diffusional kurtosis imaging in Neural circuit and post-stroke depression.
CONCLUSION: Our research indicated that the damage to WM microstructure in the frontal lobe, temporal lobe and the genu of corpus callosum may be related toPSD. DKI explores the microstructural changes of WM in PSD patients and may be an auxiliary diagnostic method for PSD. PMID: 33588692 [PubMed - as supplied by publisher]
Source: Neurological Research - February 17, 2021 Category: Neurology Tags: Neurol Res Source Type: research

Quantitative assessment and correlation analysis of cerebral microbleed distribution and leukoaraiosis in stroke outpatients.
DISCUSSION: Cerebral microbleed incidence increased with age. Mixed CMB type displayed the highest incidence. The severity and number of CMBs at any location correlated with LA severity. These results suggested interactions between hypertension and CAA during LA progression. PMID: 25875577 [PubMed - as supplied by publisher]
Source: Neurological Research - April 17, 2015 Category: Neurology Tags: Neurol Res Source Type: research

Cerebral density and perfusion measured among heart disease patients with and without stroke.
Authors: Obara K, Meyer JS, Muramatsu K, Mortel KF Abstract This' investigation was designed to clarify the chronic effects of cardiogenic emboli on cerebral perfusion and tissue densities within remaining noninfarcted brain. Local cerebral perfusion and tissue densities were measured by xenon-contrasted CT scanning and compared by cross-sectional designs among normal volunteers without heart disease (Group C, n - 44), normal volunteers with heart disease (Group N, n =20), patients with heart disease and lacunar infarctions (Group L, n = 31) and patients with heart disease associated with cardiogenic cerebral embol...
Source: Neurological Research - November 10, 2016 Category: Neurology Tags: Neurol Res Source Type: research

Internal maxillary artery to intracranial artery bypass: a case series of 31 patients with chronic internal carotid/middle cerebral arterial-sclerotic steno-occlusive disease.
CONCLUSIONS: By supplying an adequate flow to a larger flow territory of chronically stenotic/occlusive major cerebral arteries, IMA bypass surgery is efficient for restoring hemodynamics in selected patients and improving their neurological deficits. PMID: 27122096 [PubMed - as supplied by publisher]
Source: Neurological Research - April 30, 2016 Category: Neurology Tags: Neurol Res Source Type: research