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Predictors of futile recanalization after endovascular treatment in acute ischemic stroke: a meta-analysis
Conclusion This study identified female sex, comorbidities, admission systolic blood pressure, serum glucose, occlusion site, non-bridging therapy, and post-procedural complication as predictors of futile recanalization, and also confirmed previously reported factors. Further large-scale prospective studies are needed.
Source: Journal of NeuroInterventional Surgery - August 12, 2022 Category: Neurosurgery Authors: Deng, G., Xiao, J., Yu, H., Chen, M., Shang, K., Qin, C., Tian, D.-S. Tags: Ischemic stroke Source Type: research

E-136 endovascular rescue therapy post-stentriever use in large vessel occlusion; real world experience from a regional stroke network
ConclusionsTranslation of clinical trial results into real world experience is feasible and reiterates the unmet need and importance of continuing innovation to keep on improving upon current thrombectomy devices.DisclosuresK. Patel: None. P. Bhuva: None. P. Hansen: None. R. Gianatasio: None. T. Shams: None. V. Janardhan: None.
Source: Journal of NeuroInterventional Surgery - July 26, 2015 Category: Neurosurgery Authors: Patel, K., Bhuva, P., Hansen, P., Gianatasio, R., Shams, T., Janardhan, V. Tags: SNIS 12th Annual Meeting Electronic Poster Abstracts Source Type: research

P-008 Evaluating Racial/Ethnic Disparity in Endovascular Thrombectomy Outcome for Acute Stroke Patients: 4,763 patients using Premier data 2011 to 2015
ConclusionsThere were no differences in hospital outcome among races/ethnicities in endovascular thrombectomy outcomes for acute stroke patients in the Premier data. Racial/ethnic disparities play role for patients’ selection not for patients’ outcome in endovascular thrombectomy.DisclosuresS. Park: None. M. Pilot: None. M. Alexander: 1; C; Consultant for Stryker Neurovascular, Medtronic, and Penumbra, Inc. A. Rosengart: None.
Source: Journal of NeuroInterventional Surgery - July 28, 2016 Category: Neurosurgery Authors: Park, S., Pilot, M., Alexander, M., Rosengart, A. Tags: Oral poster abstracts Source Type: research

E-051 Disparities in stroke: Associating socioeconomic factors with ischemic stroke outcome
ConclusionsMedian income based on zip code is a SES indicator that is potentially associated with functional outcomes of ischemic stroke patients undergoing mechanical thrombectomy. Further studies addressing this relationship are needed.Disclosures A. Nguyen: None. G. M. Cortez: None. M. Baretta: None. A. Aghaebrahim: None. E. Sauvageau: None. R. Hanel: None.
Source: Journal of NeuroInterventional Surgery - July 26, 2021 Category: Neurosurgery Authors: Nguyen, A., Cortez, G., Baretta, M., Aghaebrahim, A., Sauvageau, E., Hanel, R. Tags: Electronic poster abstracts Source Type: research

E-086 The effect of covid-19 vaccines on stroke outcomes: a single-center study
ConclusionAlthough vaccination did not show any significant difference in stroke patient outcomes on follow-up, vaccines were associated with lower rates of morbidity and mortality at discharge among stroke patients during the pandemic.Abstract E-086 Table 1Comparison of outcomes between COVID-19-positive unvaccinated vs. fully vaccinated patients presenting with stroke.*Adjusted for hypertension, atrial fibrillation, PVD, admission NIHSS, ASPECTS, tandem occlusion, and thrombectomy Unvaccinated Vaccinated Effect Variable Unadjusted Value (95% CI ) Unadjusted p-value Adjusted Value (95% CI )* Adjusted p-value* Primary Out...
Source: Journal of NeuroInterventional Surgery - July 30, 2023 Category: Neurosurgery Authors: El Naamani, K., Amllay, A., Chen, C., Capone, S., Abbas, R., Sioutas, G., Munoz, A., Yudkoff, C., Carreras, A., Samabngi, A., Hunt, A., Jain, P., Stine, E., Sathe, A., Smit, R., Yazbeck, F., Tjoumakaris, S., Gooch, M., Herial, N., Rosenwasser, R., Zarzour Tags: SNIS 20th annual meeting electronic poster abstracts Source Type: research

E-177 Treatment of ischemic stroke in patients diagnosed with covid-19: a matched analysis of the national inpatient sample
ConclusionsIn this matched NIS analysis of patients treated for ischemic stroke with a concomitant COVID diagnosis, we demonstrate that EVT trends towards, although nonsignificant, higher rates of favorable functional outcomes when compared to medically managed patients.Abstract E-177 Table 1Patients with COVID and Acute Ischemic Stroke Comparing medical management vs EVT 1:1 Nearest Neighbor Matching for EVT based on Age, NIHSS, Gender, and Comorbidities Medically Managed N = 495 1 Endovascular ThrombectomyN = 495 1 p-value 2 Age in years at admission 66.82 ± 16.98 (19.00-90.00), (1.77) 65.67 ± 14.81 (28...
Source: Journal of NeuroInterventional Surgery - July 30, 2023 Category: Neurosurgery Authors: Heskett, C., Fry, L., Brake, A., De Stefano, F., Morey, K., Lei, C., Alkiswani, A., Le, K., Peterson, J., Ebersole, K. Tags: SNIS 20th annual meeting electronic poster abstracts Source Type: research

P-026 Extracellular vesicle neurotrophin expression in plasma collected during mechanical thrombectomy from patients with emergent large vessel stroke
DiscussionThese data suggest that EV proBDNF/BDNF levels can reflect vascular changes that lead to decreased cognition and should be explored further for translational applications.Disclosures A. Trout: None. D. Britsch: None. W. Naberhaus: None. J. Turchan-Cholewo: None. C. McLouth: None. L. Whitnel-Smith: None. J. Frank: None. J. Roberts: None. P. Shivani: None. D. Dornboss III: None. J. Harp: None. K. Pennypacker: None. A. Stowe: None. J. Fraser: None.
Source: Journal of NeuroInterventional Surgery - July 30, 2023 Category: Neurosurgery Authors: Trout, A., Britsch, D., Naberhaus, W., Turchan-Cholewo, J., McLouth, C., Whitnel-Smith, L., Frank, J., Roberts, J., Shivani, P., Dornboss, D., Harp, J., Pennypacker, K., Stowe, A., Fraser, J. Tags: SNIS 20th annual meeting oral poster abstracts Source Type: research

E-093 Carotid webs and stroke: a comprehensive overview of clinical characteristics, risk factors, and treatment modalities
ConclusionThis is the largest systematic review of CWs to date. This study provides novel information not only about risk factors and common treatment modalities for CWs, but also the relationship between CWs and stroke. This data may aid physicians in diagnosis of CWs in younger patients who present with stroke-like symptoms and no cardiovascular risk factors. Furthermore, medical treatment alone may not be as effective as stenting or surgical options.Disclosures N. Gupta: None. V. Kasulla: None. A. Shahbandi: None. J. Gendreau: None. R. Singh: None. N. Brown: None. J. Catapano: None. V. Srinivasan: None.
Source: Journal of NeuroInterventional Surgery - July 30, 2023 Category: Neurosurgery Authors: Gupta, N., Kasulla, V., Shahbandi, A., Gendreau, J., Singh, R., Brown, N., Catapano, J., Srinivasan, V. Tags: SNIS 20th annual meeting electronic poster abstracts Source Type: research

E-092 Use of balloon-guide catheters for concomitant mechanical thrombectomy and carotid revascularization with flow-arrest results in significantly lower sICH and better 90-day outcomes in tandem stroke patients
ConclusionUse of balloon-guide catheters for concomitant mechanical thrombectomy and carotid revascularization with flow-arrest results in significantly lower sICH and better 90-day outcomes in tandem stroke patients.Disclosures A. Baig: None. J. Neumaier: None. M. Waqas: None. A. Monteiro: None. J. Cappuzzo: None. W. Khawar: None. B. Donnelly: None. E. Levy: 2; C; : Claret Medical, GLG Consulting, Guidepoint Global, Imperial Care, Medtronic, Rebound, StimMed, Misionix, Mosiac, Clarion, IRRAS. 4; C; NeXtGen Biologics, RAPID Medical, Claret Medical, Cognition Medical, Imperative Care, Rebound Therapeutics, StimMed, Three Ri...
Source: Journal of NeuroInterventional Surgery - July 23, 2022 Category: Neurosurgery Authors: Baig, A., Neumaier, J., Waqas, M., Monteiro, A., Cappuzzo, J., Khawar, W., Donnelly, B., Levy, E., Siddiqui, A. Tags: SNIS 19th annual meeting electronic poster abstracts Source Type: research

Predictors of early neurologic deterioration (END) following stroke thrombectomy
Conclusions Older patients with acute ischemic stroke who have a history of diabetes or hypertension, with elevated pretreatment SBP and failed reperfusion are at a higher risk of END following stroke thrombectomy for emergent large vessel occlusion.
Source: Journal of NeuroInterventional Surgery - May 16, 2023 Category: Neurosurgery Authors: Bhole, R., Nouer, S. S., Tolley, E. A., Turk, A., Siddiqui, A. H., Alexandrov, A. V., Arthur, A. S., Mocco, J., for the COMPASS investigators Tags: Vascular neurology Source Type: research

Prediction of 90 day home time among patients with low baseline ASPECTS undergoing endovascular thrombectomy: results from Albertas Provincial Stroke Registry (QuICR)
Conclusions Patients with low ASPECTS who are selected for EVT using demographic and clinical profiles similar to higher ASPECTS patients achieved comparable outcomes.
Source: Journal of NeuroInterventional Surgery - July 14, 2023 Category: Neurosurgery Authors: Singh, N., Holodinsky, J. K., Kashani, N., McDonough, R. V., Bala, F., Horn, M., Stang, J., Demchuk, A. M., Hill, M. D., Almekhlafi, M. A. Tags: Vascular neurology Source Type: research

Clinical significance of the circle of Willis in intracranial atherosclerotic stenosis
Conclusions If patients have poor integrity of the circle of Willis, the risk of recurrent stroke may be increased. Such patients appear to be good candidates for endovascular treatment.
Source: Journal of NeuroInterventional Surgery - February 14, 2016 Category: Neurosurgery Authors: Kim, K. M., Kang, H.-S., Lee, W. J., Cho, Y. D., Kim, J. E., Han, M. H. Tags: Ischemic stroke Source Type: research

O-033 Intracranial VCAM1 at time of mechanical thrombectomy predicts ischemic stroke severity
ConclusionsThe current study provides novel data on systemic and intracranial VCAM1 in relation to stroke comorbidities, stroke severity, functional outcomes, as well as the role VCAM1 plays in complex protein-protein signaling pathways. These data will allow future studies to develop predictive biomarkers and proteomic targets for drug development to improve our ability to treat a devastating pathology.Disclosures B. Maglinger: None. M. Sands: None. J. Frank: None. C. McLouth: None. A. Trout: None. J. Roberts: None. S. Grupke: None. J. Turchan-Cholewo: None. A. Stowe: None. J. Fraser: None. K. Pennypacker: None.
Source: Journal of NeuroInterventional Surgery - July 26, 2021 Category: Neurosurgery Authors: Maglinger, B., Sands, M., Frank, J., McLouth, C., Trout, A., Roberts, J., Grupke, S., Turchan-Cholewo, J., Stowe, A., Fraser, J., Pennypacker, K. Tags: Oral abstracts Source Type: research

E-108 Endovascular treatment of patients with acute ischemic stroke due to underlying arterial dissection: a nationwide analysis
ConclusionsDespite a similar prevalence among patients admitted for AIS, CA dissections are associated with a higher rate of endovascular intervention and poorer short-term outcomes compared to VA dissections. This study provides essential epidemiologic and outcome data for the cerebrovascular neurosurgeon.Abstract E-108 Table 1Comparison of clinical characteristics and outcomes among patients presenting with acute ischemic stroke due to carotid or vertebral artery dissections Characteristic Vertebral Artery Dissection, N = 2,562 Carotid Artery Dissection, N = 2,789 p-value1 Age (years), Mean (SD) 53 (17) 57 (17) <0.00...
Source: Journal of NeuroInterventional Surgery - July 30, 2023 Category: Neurosurgery Authors: Brandel, M., McCann, C., Wali, A., Wu, V., Esmail, S., Steinberg, J., Olson, S., Pannell, J., Khalessi, A., Santiago-Dieppa, D. Tags: SNIS 20th annual meeting electronic poster abstracts Source Type: research

A lower admission level of interleukin-6 is associated with first-pass effect in ischemic stroke patients
Conclusion A lower admission level of IL-6 is associated with FPE.
Source: Journal of NeuroInterventional Surgery - February 16, 2022 Category: Neurosurgery Authors: Mechtouff, L., Bochaton, T., Paccalet, A., Crola Da Silva, C., Buisson, M., Amaz, C., Derex, L., Ong, E., Berthezene, Y., Dufay, N., Ovize, M., Mewton, N., Cho, T.-H., Nighoghossian, N., Eker, O. F. Tags: Vascular neurology Source Type: research

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