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Single-antiplatelet regimen in ruptured cerebral blood blister and dissecting aneurysms treated with flow-diverter stent reconstruction
Conclusions Peri-interventional single-antiplatelet therapy with eptifibatide followed by prasugrel was sufficient to prevent thromboembolic events and reduce re-bleeding using an anti-thrombogenic FDS. FDS with single-antiplatelet therapy might be a viable option for ruptured blood blister and dissecting cerebral aneurysms.
Source: Journal of NeuroInterventional Surgery - September 15, 2023 Category: Neurosurgery Authors: Madjidyar, J., Keller, E., Winklhofer, S., Toth, D., Barnaure, I., Schubert, T., Thurner, P., Fierstra, J., Willms, J. F., Regli, L., Kulcsar, Z. Tags: Hemorrhagic stroke Source Type: research

Relationship between cerebral vasospasm vascular territory and functional outcome after aneurysmal subarachnoid hemorrhage
Conclusions In aneurysmal SAH, left-sided vasospasm is associated with worse discharge functional status. At 6 months, both ACA and BA vasospasm are associated with unfavorable functional status.
Source: Journal of NeuroInterventional Surgery - September 15, 2023 Category: Neurosurgery Authors: Cole, T. S., Rudy, R. F., Faridmoayer, E., Gandhi, S., Cavallo, C., Catapano, J. S., Jadhav, A. P., Lawton, M. T., Albuquerque, F. C., Ducruet, A. F. Tags: Hemorrhagic stroke Source Type: research

Bridging thrombolysis improves survival rates at 90 days compared with direct mechanical thrombectomy alone in acute ischemic stroke due to basilar artery occlusion: a systematic review and meta-analysis of 1096 patients
Conclusions In patients with AIS due to BAO, bridging IVT was associated with lower mortality rates at 90 days, compared with direct MT. There were no improved functional outcomes or increased sICH or SAH between both arms, However, patients with LAA benefited from bridging IVT, with better functional outcomes.
Source: Journal of NeuroInterventional Surgery - September 15, 2023 Category: Neurosurgery Authors: Lee, K. S., Siow, I., Zhang, J. J., Syn, N. L., Gillespie, C. S., Yuen, L. Z., Anil, G., Yang, C., Chan, B. P., Sharma, V. K., Teoh, H.-L., Mingxue, J., Teo, K. S. H., Myint, M. Z., Bhogal, P., Meyer, L., Schob, S., Sia, C.-H., Mpotsaris, A., Maus, V., An Tags: Vascular neurology Source Type: research

Endovascular therapy for acute ischemic stroke in patients with active malignancy: a meta-analysis with trial sequential analysis
Conclusion Although a quarter of patients with active malignancy and AIS regained functional independence, physicians and patients should consider whether to apply EVT in patients with active malignancy.
Source: Journal of NeuroInterventional Surgery - August 29, 2023 Category: Neurosurgery Authors: Jhou, H.-J., Yang, L.-Y., Chen, P.-H., Lee, C.-H. Tags: Ischemic stroke Source Type: research

P124/272 Initial encounter with a cutting-edge mobile head CT scanner (Somatom On.site) in a neuro-intensive care unit
ConclusionThe study demonstrates the clinical effectiveness of modern mobile CT scanners in neurointensive care units. The Somatom On.site provides sufficient image quality, saves time and supports timely decision making. The integration of mobile CT scanners in NICUs improves patient care and workflow. Prospective studies are needed to validate these findings and assess the long-term impact in NICUs and other units, such as stroke units.Disclosure of InterestCK serves as consultants for Acandis GmbH (Pforzheim, Germany) and proctor for MicroVention Inc./Sequent Medical (Aliso Viejo, CA, USA).
Source: Journal of NeuroInterventional Surgery - August 21, 2023 Category: Neurosurgery Authors: Goertz, L., Al-Sewaidi, Y., Habib, M., Ranft, A., Kabbasch, C. Tags: 3.1 OTHER - Innovation Source Type: research

P156/208 Association between arterial diameter and outcome in acute M2 occlusive ischemic stroke patients treated with endovascular thrombectomy
ConclusionThis study demonstrated that the lowest quartile of M2 diameter was associated with procedural complication in the acute M2 occlusion patients treated with EVT. However, clinical outcome was not differed.Disclosure of InterestNothing to disclose
Source: Journal of NeuroInterventional Surgery - August 21, 2023 Category: Neurosurgery Authors: Kim, J. Y., Kim, D. Y., Kang, J., Kim, B. J., Han, M.-K., Bae, H.-J., Baik, S. H., Jung, C. Tags: 2.3 ISCHEMIC - Treatment Source Type: research

O15/151 Impact of post-thrombectomy isolated subarachnoid hemorrhage and other types of intracranial hemorrhage on neurological outcomes in patients with anterior circulation ischemic stroke - reperfusion grade determines
ConclusionPost-thrombectomy i-SAH is an important complication as it might aggravate patient’s neurological impairment, particularly in case of incomplete reperfusion.Disclosure of InterestNothing to disclose.
Source: Journal of NeuroInterventional Surgery - August 21, 2023 Category: Neurosurgery Authors: Landeghem, N. v., Ziegenfuss, C., Demircioglu, A., Dammann, P., Jabbarli, R., Haubold, J., Forsting, M., Wanke, I., Köhrmann, M., Frank, B., Deuschl, C., Li, Y. Tags: 2.3 ISCHEMIC - Treatment Source Type: research

P031/333 A very rare complication during mechanical thrombectomy: the breakage of the aspiration catheters tip and his rescue
ConclusionBreakage and retention of the thrombectomy devices represents a very rare cause of complications during mechanical thrombectomy but nevertheless possible. We have reported this case, with its related treatment, in order to help the management of this type of complication.Disclosure of InterestDr. D.G. Romano consultant and proctor for BALT Italy, Microvention Europe, Penumbra Inc.
Source: Journal of NeuroInterventional Surgery - August 21, 2023 Category: Neurosurgery Authors: Tortora, R., Flora, G., Frauenfelder, G., Locatelli, G., Siani, A., Saponiero, R., Romano, D. Tags: 4.4 CASE PROPOSAL - Complications Source Type: research

Decoding the data: a comment on the American Heart Association/American Stroke Association (AHA/ASA) 2023 Guideline for the Management of patients with Aneurysmal Subarachnoid Hemorrhage
Guideline summary The 2023 Guideline for the Management of Patients With Aneurysmal Subarachnoid Hemorrhage was recently released with endorsements from multiple societies, including the Society of NeuroInterventional Surgery.1 All who worked on this document should be congratulated for their work, as it provides many updates, and addresses new components of aneurysmal subarachnoid hemorrhage (aSAH) care. We encourage providers to thoroughly read the statement. While this Guideline statement is thorough, it is important to highlight opportunities for future research, and gaps in the literature, where rigorous adherence to ...
Source: Journal of NeuroInterventional Surgery - August 17, 2023 Category: Neurosurgery Authors: Fraser, J. F., Heit, J. J., Mascitelli, J. R., Tsai, J. P. Tags: Commentary Source Type: research

LB-004 Novel saccular endovascular aneurysm lattice (SEAL device) pre-seal it early clinical feasibility trial: procedural, 24-hours, and 3-month safety and effectiveness independent core lab adjudicated outcomes
ConclusionThe final procedural, 24-hour, and 3-month follow-up results of the PRE-SEAL-IT trial demonstrated promising occlusion rates at post-procedural, 24-hour, and 3 months follow-up with no safety concerns.DisclosuresB. Pabón: None. V. Torres: None. S. Zaidi: None. H. Salahuddin: None. M. Patiño: None. F. Peláez: None. J. Mútis: None. M. Cardozo: None. A. Hussain: None. I. Lutfi: None. M. Ali: None. S. Ahmed: None. E. Pereira: None. A. Badruddin: None. K. Woodward: None. T. Wolfe: None. C. Langerford: None. B. Jankowitz: None. V. Costalat: None. D. Altschell: None. M. Kaffashi: None. O. Zaidat: None.
Source: Journal of NeuroInterventional Surgery - August 3, 2023 Category: Neurosurgery Authors: Pabon, B., Torres, V., Zaidi, S., Salahuddin, H., Patino, M., Pelaez, F., Mutis, J., Cardozo, M., Hussain, A., Lutfi, I., Ali, M., Ahmed, S., Pereira, E., Badruddin, A., Woodward, K., Wolfe, T., Langerford, C., Jankowitz, B., Costalat, V., Altschell, D., Tags: SNIS 20th annual meeting late-breaking oral abstracts Source Type: research

E-078 Advancement in coil technology for treatment of brain aneurysms
ConclusionThis study concludes that is SMART coil system is safe and efficacious for the use in Endovascular treatment of intracranial aneurysms. The smart coil system is promising in the treatment of wide spectrum of intracranial aneurysms. The result of follow up angiographic data should reflect the high packing density and will be published when completed.Disclosures S. Khairandish: None. S. Pakbaz: None. M. McManus: None. G. Ammirati: None.
Source: Journal of NeuroInterventional Surgery - July 30, 2023 Category: Neurosurgery Authors: Khairandish, S., Pakbaz, S., McManus, M., Ammirati, G. Tags: SNIS 20th annual meeting electronic poster abstracts Source Type: research

E-108 Endovascular treatment of patients with acute ischemic stroke due to underlying arterial dissection: a nationwide analysis
ConclusionsDespite a similar prevalence among patients admitted for AIS, CA dissections are associated with a higher rate of endovascular intervention and poorer short-term outcomes compared to VA dissections. This study provides essential epidemiologic and outcome data for the cerebrovascular neurosurgeon.Abstract E-108 Table 1Comparison of clinical characteristics and outcomes among patients presenting with acute ischemic stroke due to carotid or vertebral artery dissections Characteristic Vertebral Artery Dissection, N = 2,562 Carotid Artery Dissection, N = 2,789 p-value1 Age (years), Mean (SD) 53 (17) 57 (17) <0.00...
Source: Journal of NeuroInterventional Surgery - July 30, 2023 Category: Neurosurgery Authors: Brandel, M., McCann, C., Wali, A., Wu, V., Esmail, S., Steinberg, J., Olson, S., Pannell, J., Khalessi, A., Santiago-Dieppa, D. Tags: SNIS 20th annual meeting electronic poster abstracts Source Type: research

E-126 Multicenter flow diversion in 200 patients for treatment of intracranial aneurysms
ConclusionThis report characterizes patient demographics, aneurysm characteristics, procedure complications and long-term angiographic and clinical outcomes for a large patient population across multiple medical centers treated with flow diversion. Overall, procedures resulted in a high rate of occlusion and low rate of serious complications. Continued iterative outcomes analysis is warranted particularly as flow diversion technology evolves. Despite diverse hospital settings, differences in presentation, patient characteristics and the inclusion of off-label treatments, flow diversion procedures remained safe and effectiv...
Source: Journal of NeuroInterventional Surgery - July 30, 2023 Category: Neurosurgery Authors: Meister, R., Lesko, A., Marginean, H., Deshmukh, V. Tags: SNIS 20th annual meeting electronic poster abstracts Source Type: research

P-028 Impact of the covid-19 pandemic on the intracranial aneurysm treatment and associated outcomes: a propensity score matching study
Conclusions and RelevanceThe COVID-19 pandemic has significantly impacted the healthcare system and has led to changes in the treatment of various neurological conditions, including ICAs. The pandemic resulted in a shift in the treatment of SAH and an increase in endovascular procedures over open surgical clipping. COVID-19 infection has been associated with an increased risk of ischemic stroke and worsened outcomes for stroke patients. Further research is necessary to understand the long-term effects of the pandemic on the healthcare system and patient outcomes.Disclosures A. Ghaith: None. M. Ghanem: None. E. Greco: None....
Source: Journal of NeuroInterventional Surgery - July 30, 2023 Category: Neurosurgery Authors: Ghaith, A., Ghanem, M., Greco, E., Rios-Zermeno, J., Bon Nieves, A., Kashyap, S., Tawk, R., Bydon, M. Tags: SNIS 20th annual meeting oral poster abstracts Source Type: research

E-020 Flow diversion for intracranial aneurysms: intracranial hemorrhage and thromboembolic complications in a multi-center cohort of 200 patients
ConclusionComplication rates in our study are comparable to previous reports, and our findings further support the general safety and efficacy of flow diversion. Despite a relatively large population, the low number of ICH and TE complications limit statistical significance. Further study of complications in more robust samples are needed. However, the descriptive understanding of these complications can help direction future investigations.Abstract E-020 Table 1ICH and TE Stratifications ICH Non-ICH p n=7 n=193 Hypertension 7 (100%) 97 (50.3%) 0.035 Currently Smoking 3 (42.9%) 28 (14.5%) 0.319 Mean Procedural Fluoroscopi...
Source: Journal of NeuroInterventional Surgery - July 30, 2023 Category: Neurosurgery Authors: Meister, R., Lesko, A., Marginean, H., Deshmukh, V. Tags: SNIS 20th annual meeting electronic poster abstracts Source Type: research

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