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E-189 Outcomes of tenecteplase versus alteplase after mechanical thrombectomy in a multiethnic stroke consortium registry
ConclusionIn this prospective, multi-center stroke consortium study, IV TNK in comparison to tPA prior to MT for ischemic stroke resulted in non-inferior outcomes related to angiographic reperfusion and functional status at discharge. These findings compliment the current literature and include a large Hispanic US cohort. Further analysis will include expansion of contributing centers and use of propensity scoring.Abstract E-189 Table 1 and 2Disclosures M. Gaub: None. D. Ramaswamy: None. A. Cardentey: None. S. Bandela: None. G. Gealogo: None. J. Mascitelli: None. F. Al Saiegh: None. L. Birnbaum: 2; C; Rapid AI, Imperative Care.
Source: Journal of NeuroInterventional Surgery - July 30, 2023 Category: Neurosurgery Authors: Gaub, M., Ramaswamy, D., Cardentey, A., Bandela, S., Gealogo, G., Mascitelli, J., Al Saiegh, F., Birnbaum, L. Tags: SNIS 20th annual meeting electronic poster abstracts Source Type: research

First-line thrombectomy strategy for distal and medium vessel occlusions: a systematic review
Conclusions Our systematic review supports the proposition that MT is a safe and effective treatment option for DMVOs. Additionally, while the SR+ASP group had consistently high rates of clot clearance and good neurological outcomes, the SR and SR+ASP groups also had higher rates of subarachnoid hemorrhage, highlighting the need for improved DMVO treatment devices.
Source: Journal of NeuroInterventional Surgery - May 16, 2023 Category: Neurosurgery Authors: Bilgin, C., Hardy, N., Hutchison, K., Pederson, J. M., Mebane, A., Olaniran, P., Kobeissi, H., Kallmes, K. M., Fiorella, D., Kallmes, D. F., Brinjikji, W. Tags: Ischemic stroke Source Type: research

Distal cerebral vasospasm treatment following aneurysmal subarachnoid hemorrhage using the Comaneci device: technical feasibility and single-center preliminary results
Conclusion This initial experience suggests that distal mechanical angioplasty performed with the Comaneci-17 device for refractory vasospasm following aSAH seems to be safe, with good feasibility and efficacy.
Source: Journal of NeuroInterventional Surgery - March 14, 2023 Category: Neurosurgery Authors: Thiery, L., Carle, X., Testud, B., Boulouis, G., Habert, P., Tradi, F., Reyre, A., Lehmann, P., Dory-Lautrec, P., Stellmann, J.-P., Girard, N., Brunel, H., Hak, J.-F. Tags: Hemorrhagic stroke Source Type: research

Higher Hospital Frailty Risk Score is associated with increased complications and healthcare resource utilization after endovascular treatment of ruptured intracranial aneurysms
Conclusions Our study found that greater frailty as defined by the HFRS was associated with increased complications, LOS, total costs, and non-routine discharge.
Source: Journal of NeuroInterventional Surgery - February 14, 2023 Category: Neurosurgery Authors: Koo, A. B., Elsamadicy, A. A., Renedo, D., Sarkozy, M., Sherman, J., Reeves, B. C., Havlik, J., Antonios, J., Sujijantarat, N., Hebert, R., Malhotra, A., Matouk, C. Tags: Hemorrhagic stroke, COVID-19 Source Type: research

First clinical multicenter experience with the new Pipeline Vantage flow diverter
Conclusions The new PV FD is safe and feasible for the treatment of intracranial aneurysms. The short-term occlusion rates are promising but need further assessment in prospective long-term follow-up studies.
Source: Journal of NeuroInterventional Surgery - December 14, 2022 Category: Neurosurgery Authors: Vollherbst, D. F., Cekirge, H. S., Saatci, I., Baltacioglu, F., Onal, B., Koc, O., Rautio, R., Sinisalo, M., Tomasello, A., Vega, P., Martinez-Galdamez, M., Lynch, J., Mendes Pereira, V., Bendszus, M., Möhlenbruch, M. A. Tags: New devices New devices and techniques Source Type: research

Antiplatelet therapy for standalone coiling of ruptured intracranial aneurysms: a systematic review and meta-analysis
Conclusions Although this study showed no beneficial effect of AT on clinical outcomes, the results suggest that AT could be combined with standalone coiling to avoid thromboembolism during the perioperative period. A large prospective study and/or an additional meta-analysis would be required to further investigate how AT benefits standalone coil embolization in aSAH.
Source: Journal of NeuroInterventional Surgery - November 14, 2022 Category: Neurosurgery Authors: Takase, H., Tatezuki, J., Salem, M. M., Tayama, K., Nakamura, Y., Burkhardt, J.-K., Yamamoto, T. Tags: Hemorrhagic stroke Source Type: research

Distribution of symptomatic cerebral vasospasm following subarachnoid hemorrhage assessed using cone-beam CT angiography
Conclusions Our study demonstrated that symptomatic cerebral vasospasm following aSAH did not involve arteries smaller than 900 µm, and frequently predominated in middle or distal segments. These results offer new insights into the potential management options for vasospasm using PBA.
Source: Journal of NeuroInterventional Surgery - October 14, 2022 Category: Neurosurgery Authors: Simonato, D., Borchert, R. J., Vallee, F., Joachim, J., Civelli, V., Cancian, L., Houdart, E., Labeyrie, M.-A. Tags: Hemorrhagic stroke Source Type: research

Comparing the efficacy and safety of the Skyflow device with those of the Solitaire FR stent in patients with acute ischemic stroke: a prospective, multicenter, randomized, non-inferiority clinical trial
Conclusion Endovascular thrombectomy with the Skyflow stent retriever was non-inferior to Solitaire FR with regard to successful reperfusion in AIS due to LVO (with a pre-specified non-inferiority margin of 12.5%).
Source: Journal of NeuroInterventional Surgery - October 14, 2022 Category: Neurosurgery Authors: Zhou, T., Li, T., Zhu, L., Li, Z., Li, Q., Bai, W.-x., He, Y.-k., Liu, X., Guan, H., Long, Y., Liu, J., Wei, L., Nan, G., Li, H., Wen, C., Zhang, Y., Qiao, H., Han, J., Wang, S., Gu, J., Cai, X., Liu, S., Zhao, Z. Tags: New devices and techniques Source Type: research

Endovascular treatment of ruptured anterior communicating aneurysms: a 17-year institutional experience with coil embolization
Conclusions Endovascular treatment of ruptured ACoA aneurysms is safe and is associated with low mortality and retreatment rates. Younger patients with favorable functional status and larger aneurysm size are more likely to be retreated. Ruptured aneurysms <4 mm, although prevalent in the study (29%), never required retreatment.
Source: Journal of NeuroInterventional Surgery - September 14, 2022 Category: Neurosurgery Authors: Catapano, J. S., Karahalios, K., Rumalla, K., Srinivasan, V. M., Rutledge, C., Baranoski, J. F., Cole, T. S., Jadhav, A. P., Ducruet, A. F., Albuquerque, F. C. Tags: Hemorrhagic stroke Source Type: research

O23 Mechanical thrombectomy using a modified ADAPT (a direct aspiration first pass technique) in a patient with m1-occlusion and concomitant mca-aneurysm
We present a case in which a patient with a right-sided MCA M1 occlusion (NIHSS 30) and concomitant mediabifurcation aneurysm was fully recanalized (TICI 3) using a modified ADAPT technique, without prior passage of the thrombus as previously described by Turc et al.2. To us, the avoidance of blind aneurysm passage by microwire and microcatheter appears to be a major advantage of the method used. Instead, the aspiration catheter was advanced via a 0.035 Terumo guide wire for proximal stabilization. Thrombus was aspirated with proximally inflated BGC and repeated imaging series up to visualization of the aneurysm neck. Thus...
Source: Journal of NeuroInterventional Surgery - August 29, 2022 Category: Neurosurgery Authors: Demerath, T., Elbaz, A., Urbach, H., Taschner, C. Tags: 14th Congress of the European Society of Minimally Invasive Neurological Therapy 2022 Meeting Abstracts Source Type: research

P08 Detection of cerebral aneurysms in unenhanced CT images of patients with subarachnoid hemorrhage using the sparing aneurysm sign (SAS)
ConclusionsThe aneurysm location and size can be determined in unenhanced CT images in many cases using the new SAS (sparing aneurysm sign). Whereas quantitative measurements of HU can support the aneurysm detection.ReferencesConnolly ES, Rabinstein AA, Carhuapoma JR, et al. Guidelines for the Management of Aneurysmal Subarachnoid Hemorrhage. Stroke. 2012;43. Do you have any conflict of interest to declare?: No
Source: Journal of NeuroInterventional Surgery - August 29, 2022 Category: Neurosurgery Authors: Peters, S., Klintz, T., Larsen, N., Hensler, J., Wodarg, F., Jansen, O. Tags: 14th Congress of the European Society of Minimally Invasive Neurological Therapy 2022 Meeting Abstracts Source Type: research

P16 Semi-emergent management of ruptured intracranial blood blister-like aneurysms: single centre experience
ConclusionsOur endovascular treatment approach for ruptured blister aneurysms is safe and effective, with a low risk of procedural complications and favourable clinical outcomes.ReferencesPeschillo, S et al. "A Systematic Review and Meta-analysis of Treatment and Outcome of Blister-like Aneurysms." AJNR. American Journal of Neuroradiology Vol. 37,5 (2016): 856–61. DOI:10.3174/AJNR.A4606.Nasra, Mohamed et al. "Contemporary Treatment of Intracranial Blood Blister Aneurysms – A Systematic Review." Journal of Stroke and Cerebrovascular Diseases: The Official Journal of National Stroke Association Vol. 30,9 (2021): ...
Source: Journal of NeuroInterventional Surgery - August 29, 2022 Category: Neurosurgery Authors: Abou-Foul, M., Balian, V., Chotai, A., Demetriou, V., White, P., Padmanabhan, R., Gan, C. Tags: 14th Congress of the European Society of Minimally Invasive Neurological Therapy 2022 Meeting Abstracts Source Type: research

P18 Acute flow diversion with Pipeline Flex and Pipeline Vantage with Shield technology with single antiplatelet cover - short term results
ConclusionPipeline Flex and Vantage with Shield technology with phosphoryl choline surface modification is safe with no mortality and acceptable morbidity with single antiplatelet intra-operative cover. Initial results showed excellent occlusion and good clinical outcomes.ReferencesMahajan A, Das B, Narang KS, et al. Surpass Flow Diverter in the Treatment of Ruptured Intracranial Aneurysms-A Single-Center Experience. World Neurosurg. 2018 Dec;120:E1061-E1070. DOI: 10.1016/J.WNEU.2018.09.011. EPUB 2018 Sep 11. PMID: 30213677.Gopinathan A, Jain S, Lwin S, et al. Flow diversion in acute sub arachnoid haemorrhage: a single cen...
Source: Journal of NeuroInterventional Surgery - August 29, 2022 Category: Neurosurgery Authors: Skinner, N., Galea, J., Van Beijnum, J., Mattar, G., Sastry, A. Tags: 14th Congress of the European Society of Minimally Invasive Neurological Therapy 2022 Meeting Abstracts Source Type: research

P25 Short- and long-term mortality of subarachnoid hemorrhage according to hospital volume and severity using a nationwide multicenter stroke registry
ConclusionShort- and long-term mortality in patients with SAH differed according to hospital volume. In the modern endovascular era, clipping and coiling can lead to better outcomes in facilities with high stroke-care capabilities.ReferencesPobereskin LH. Incidence and outcome of subarachnoid haemorrhage: a retrospective population based study. J Neurol Neurosurg Psychiatry 2001;70:340–3. DOI:10.1136/JNNP.70.3.340.Lee JY, Heo NH, Lee MR, Ahn JM, Oh HJ, Shim JJ, et al. Short and long-term outcomes of subarachnoid hemorrhage treatment according to hospital volume in korea: a nationwide multicenter registry. J Korean Me...
Source: Journal of NeuroInterventional Surgery - August 29, 2022 Category: Neurosurgery Authors: Oh, J. Tags: 14th Congress of the European Society of Minimally Invasive Neurological Therapy 2022 Meeting Abstracts Source Type: research

P29 FD use in acutely presented dissecting aneurysms, 2 years follow up of 53 cases
ConclusionsFlow diverters might be a feasible, alternative treatment option for acutely symptomatic dissecting aneurysms and may effectively prevent rebleeding in ruptured aneurysms.ReferencesWalcott B.P., Koch M.J., Stapleton C.J., Patel A.B. Blood flow diversion as a primary treatment method for ruptured brain aneurysms-concerns, controversy, and future directions. Neurocritical Care 2017;26:465–473. DOI: 10.1007/S12028-016-0318-Y. -Cagnazzo F., Di Carlo D.T., Cappucci M., Lefevre P.H., Costalat V., Perrini P. Acutely ruptured intracranial aneurysms treated with flow-diverter stents: a systematic review and meta-an...
Source: Journal of NeuroInterventional Surgery - August 29, 2022 Category: Neurosurgery Authors: Mansour, O., Hassan, T., Hassan, F. Tags: 14th Congress of the European Society of Minimally Invasive Neurological Therapy 2022 Meeting Abstracts Source Type: research

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