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Impact of early enteral nutrition on short term prognosis after acute stroke
Publication date: Available online 14 July 2015 Source:Journal of Clinical Neuroscience Author(s): Tianheng Zheng , Xinpu Zhu , Huazheng Liang , Haixia Huang , Jiandao Yang , Shaoshi Wang We hypothesized that early enteral nutritional support would improve the short term prognosis of acute stroke patients with dysphagia, demonstrated by lower malnutrition rates, lower complication rates, and lower National Institutes of Health Stroke Scale (NIHSS) scores at 90days post stroke. Nutrition support is an essential element in the care of stroke patients and many studies have investigated the effect of specific nutritional ele...
Source: Journal of Clinical Neuroscience - July 14, 2015 Category: Neuroscience Source Type: research

Magnetisation transfer parameters and stroke outcome
Publication date: Available online 16 April 2015 Source:Journal of Clinical Neuroscience Author(s): I. Sibon , T. Tourdias , S. Felix , J. Asselineau , L. Bracoud , A. Vivot , F. Rouanet , P. Renou , J.M. Orgogozo , V. Dousset Our aim was to evaluate the association between magnetisation transfer imaging (MTI) parameters measured 30 to 45days after a cerebrovascular insult and post-stroke functional outcome at the same time. MTI offers the opportunity to depict subtle microstructural changes in infarcted areas. The clinical significance of the heterogeneity of brain damage within ischaemic stroke lesions is unknown. We p...
Source: Journal of Clinical Neuroscience - April 28, 2015 Category: Neuroscience Source Type: research

Predictors of malignant brain edema in middle cerebral artery infarction observed on CT angiography
Publication date: March 2015 Source:Journal of Clinical Neuroscience, Volume 22, Issue 3 Author(s): Hoon Kim , Seon Tak Jin , Young Woo Kim , Seong Rim Kim , Ik Seong Park , Kwang Wook Jo Patients with middle cerebral artery (MCA) infarction accompanied by MCA occlusion with or without internal carotid artery (ICA) occlusion have a poor prognosis, as a result of brain cell damage caused by both the infarction and by space-occupying and life-threatening edema formation. Multiple treatments can reduce the likelihood of edema formation, but tend to show limited efficacy. Decompressive hemicraniectomy with duroplasty has bee...
Source: Journal of Clinical Neuroscience - February 16, 2015 Category: Neuroscience Source Type: research

Downregulation of serum brain specific microRNA is associated with inflammation and infarct volume in acute ischemic stroke
Publication date: February 2015 Source:Journal of Clinical Neuroscience, Volume 22, Issue 2 Author(s): Yanping Liu , Junjian Zhang , Rongfei Han , Hanxing Liu , Dong Sun , Xuan Liu Cerebral ischemic injury activates a robust inflammatory response, exacerbating neurological deficit. Several brain specific microRNA (miRNA) molecules have been reported to mediate functioning of the immune system, referred to as NeurimmiR. We aimed to explore possible associations between serum miRNA levels and stroke severity and their involvement in the regulation of inflammatory responses after stroke. Blood samples were obtained from 31 ...
Source: Journal of Clinical Neuroscience - January 14, 2015 Category: Neuroscience Source Type: research

Saving the ischemic penumbra: Endovascular thrombolysis versus medical treatment
We present the first study to our knowledge comparing the ischemic penumbra saved with endovascular versus medical therapy. A retrospective review of 21 patients undergoing endovascular intervention for stroke from 2010 to 2011 was contrasted with 21 consecutive patients treated with antiplatelet agents alone. Immediate computed tomography perfusion (CTP) scan of the head and neck was obtained in all patients. Patients with lacunar and posterior circulation infarcts, and those who were medically unstable for MRI post-operatively were excluded. CTP and MRI underwent volumetric calculation. CTP penumbra was correlated with d...
Source: Journal of Clinical Neuroscience - November 29, 2014 Category: Neuroscience Source Type: research

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