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Source: Journal of Clinical Neuroscience
Management: National Institutes of Health (NIH)
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Total 20 results found since Jan 2013.
Prevalence of hypohydration and its association with stroke severity and independence outcomes in acute ischemic stroke patients
Publication date: Available online 11 December 2019Source: Journal of Clinical NeuroscienceAuthor(s): Alex Buoite Stella, Marina Gaio, Giovanni Furlanis, Mariana Ridolfi, Miloš Ajčević, Arianna Sartori, Paola Caruso, Shawnda A. Morrison, Marcello Naccarato, Paolo ManganottiAbstractHypohydration has been suggested increasing the risk of vascular diseases, and it is associated with poor prognosis and worse functional outcome in stroke. Most studies have used blood parameters to determine patients’ hydration status. The aim of this study was to measure urine osmolality (uOsm) and its influence on stroke severity and inde...
Source: Journal of Clinical Neuroscience - December 12, 2019 Category: Neuroscience Source Type: research
Clinical outcomes of moderate to severe acute ischemic stroke in a telemedicine network
The objective of this study was to analyze clinical and imaging based outcomes of moderate to severe stroke following treatment with thrombolysis, thrombectomy or a combination of both in a telemedicine network. Data of this retrospective study was abstracted from the institutional telestroke database. Patients with a National Institute of Health Stroke Scale score (NIH-SS ≥ 10) were included into the study. Primary outcome measure was the difference in NIH-SS at admission compared to discharge from the hospital. Secondary outcome measure was the discharge disposition defined as favorable (discharge to home or rehabi...
Source: Journal of Clinical Neuroscience - November 2, 2019 Category: Neuroscience Source Type: research
Brachial-ankle pulse wave velocity for predicting functional outcomes in patients with cryptogenic stroke
Publication date: Available online 18 July 2019Source: Journal of Clinical NeuroscienceAuthor(s): Minho Han, Young Dae Kim, Hyung Jong Park, In Gun Hwang, Junghye Choi, Jimin Ha, Ji Hoe Heo, Hyo Suk NamAbstractEven after extensive standard evaluation, the probable cause of stroke in some patients remains unclear; this condition is defined as cryptogenic stroke (CS). The prognosis of patients with CS is largely undetermined. We investigated whether higher brachial-ankle pulse wave velocities (baPWVs) can predict poor functional outcomes at 3 months after stroke onset in these patients. We investigated patients with CS wit...
Source: Journal of Clinical Neuroscience - July 20, 2019 Category: Neuroscience Source Type: research
A troponin study on patients with ischemic stroke, intracerebral hemorrhage and subarachnoid hemorrhage: Type II myocardial infarction is significantly associated with stroke severity, discharge disposition and mortality
Publication date: Available online 20 April 2019Source: Journal of Clinical NeuroscienceAuthor(s): Ayham M. Alkhachroum, Benjamin Miller, Tarek Chami, Curtis Tatsuoka, Cathy SilaAbstractTroponin elevations due to Type II myocardial infarction (T2MI) are associated with hemorrhagic and ischemic strokes but there is little data on stroke severity, troponin elevation and outcome. We studied 1655 patients from a tertiary medical center between 1/2013-4/2015 using multivariate regression analysis for demographics, vascular risk factors, admission stroke severity, laboratory tests, echocardiogram results and discharge dispositio...
Source: Journal of Clinical Neuroscience - April 21, 2019 Category: Neuroscience Source Type: research
Blood microRNA-93 as an indicator for diagnosis and prediction of functional recovery of acute stroke patients
Publication date: Available online 19 December 2018Source: Journal of Clinical NeuroscienceAuthor(s): Qingfeng Ma, Guangwen Li, Zhen Tao, Jue Wang, Rongliang Wang, Ping Liu, Yumin Luo, Haiping ZhaoAbstractThe present study evaluated the diagnostic and predictive potential of microRNA-93 in acute ischemic stroke (AIS) patients within 6 h of stroke onset and its regulation on microglial inflammation in vitro. Our results showed that the miR-93 levels in plasma and neutrophil detected by real-time PCR were evidently reduced in AIS patients, and Pearson's correlation analysis showed that miR-93 levels in plasma and neutrophi...
Source: Journal of Clinical Neuroscience - December 20, 2018 Category: Neuroscience Source Type: research
Thrombectomy in stroke of unknown onset, wake up stroke and late presentations: Australian experience from 2 comprehensive stroke centres
This study shows good ‘real world’ outcomes, comparable to published RCTs, in patients with unknown-onset, or late presentation, stroke treated with EVT more than 6 h from stroke onset.
Source: Journal of Clinical Neuroscience - November 8, 2018 Category: Neuroscience Source Type: research
Association of lower leukocyte count before thrombolysis with early neurological improvement in acute ischemic stroke patients
Publication date: Available online 17 August 2018Source: Journal of Clinical NeuroscienceAuthor(s): Canhui Tian, Zhong Ji, Wei Xiang, Xiaomei Huang, Shengnan Wang, Yongmin Wu, Suyue Pan, Liang Zhou, Zhen DengAbstractEarly neurological improvement (ENI) after thrombolysis in acute ischemic stroke is associated with a favorable long-term outcome. With the goal to evaluate ENI, we aimed to investigate whether ENI bears a relationship with routine blood tests before thrombolysis. A total of 240 patients with confirmed early ischemic stroke and intravenous recombinant tissue plasminogen activator (rtPA) treatment were enrolled ...
Source: Journal of Clinical Neuroscience - August 17, 2018 Category: Neuroscience Source Type: research
Factors associated with early dramatic recovery following successful recanalization of occluded artery by endovascular treatment in anterior circulation stroke
Publication date: Available online 3 October 2017 Source:Journal of Clinical Neuroscience Author(s): Dae-Hyun Kim, Hyun-Wook Nah, Hyun-Seok Park, Jae-Hyung Choi, Myung-Jin Kang, Jae-Kwan Cha Endovascular treatment (EVT) significantly increases the recanalization rate and improves functional outcomes in acute ischemic stroke. However, despite successful recanalization by EVT, some stroke patients demonstrate no early dramatic recovery (EDR). We assessed factors associated with EDR following recanalization by EVT. We included subjects with anterior circulation stroke treated with EVT who met the following criteria: Thrombol...
Source: Journal of Clinical Neuroscience - October 3, 2017 Category: Neuroscience Source Type: research
Evaluation of the role of susceptibility-weighted imaging in thrombolytic therapy for acute ischemic stroke
Publication date: Available online 20 February 2017 Source:Journal of Clinical Neuroscience Author(s): Guangjian Zhao, Ling Sun, Ziran Wang, Liquan Wang, Zhongrong Cheng, Hongyan Lei, Daiqun Yang, Yansen Cui, Shirui Zhang We inspected low-intensity venous signals and microbleeds in patients with acute ischemic stroke (AIS) using susceptibility-weighted imaging (SWI) before and after administration of within-thrombolytic-time-window thrombolytic therapies, and observed their prognosis and safety, in order to guide individualized thrombolytic therapies. Patients with AIS were divided into groups A or B according to the pres...
Source: Journal of Clinical Neuroscience - February 20, 2017 Category: Neuroscience Source Type: research
Prediction of favorable outcome by percent improvement in patients with acute ischemic stroke treated with endovascular stent thrombectomy
Publication date: Available online 20 January 2017 Source:Journal of Clinical Neuroscience Author(s): Yuezhou Cao, Shuiping Wang, Wen Sun, Qiliang Dai, Wei Li, Jin Cai, Xinying Fan, Wusheng Zhu, Yunyun Xiong, Yunfei Han, Wenjie Zi, Shiquan Yang, Jia Chen, Xinfeng Liu Our objective was to investigate a method for assessing early improvement and its predictive value for 3-month functional outcome in patients treated with EST. A total of 97 consecutive AIS patients undergoing EST were prospectively collected and retrospective reviewed. Data on demographics, vascular risk factors, admission National Institutes of Health Strok...
Source: Journal of Clinical Neuroscience - January 19, 2017 Category: Neuroscience Source Type: research
Mechanical thrombectomy with the Solitaire AB stent for treatment of acute basilar artery occlusion: A single-center experience
Publication date: October 2016 Source:Journal of Clinical Neuroscience, Volume 32 Author(s): Shiwei Du, Gengsheng Mao, Dongmei Li, Ming Qiu, Qingbin Nie, Haibo Zhu, Yang Yang, Youping Zhang, Youxiang Li, Zhongxue Wu Basilar artery occlusion (BAO) remains one of the most devastating subtypes of ischemic stroke, and prognosis is poor if early recanalization is not achieved. The purpose of this study was to evaluate the safety and technical feasibility of mechanical thrombectomy with the Solitaire AB stent (Covidien, Irvine, CA, USA) for the treatment of acute BAO through a single-center experience. Twenty-one patients with ...
Source: Journal of Clinical Neuroscience - August 31, 2016 Category: Neuroscience Source Type: research
International benchmarking for acute thrombolytic therapy implementation in Australia and Japan
Publication date: July 2016 Source:Journal of Clinical Neuroscience, Volume 29 Author(s): Hiroyuki Kawano, Christopher Levi, Yuichiro Inatomi, Heather Pagram, Erin Kerr, Andrew Bivard, Neil Spratt, Ferdinand Miteff, Toshiro Yonehara, Yukio Ando, Mark Parsons Although a wide range of strategies have been established to improve intravenous tissue plasminogen activator (IV-tPA) treatment rates, international benchmarking has not been regularly used as a systems improvement tool. We compared acute stroke codes (ASC) between two hospitals in Australia and Japan to study the activation process and potentially improv...
Source: Journal of Clinical Neuroscience - May 29, 2016 Category: Neuroscience Source Type: research
Emergency endovascular revascularization of tandem occlusions: Internal carotid artery dissection and intracranial large artery embolism
We present our recent experience in the endovascular management of occlusive ICAD and major intracranial occlusion. Consecutive anterior circulation acute stroke patients meeting Medical Center criteria for endovascular management of ICAD from June 2011 to June 2015 were included. Clinical, imaging, and procedure data were collected retrospectively under Institutional Review Board approval. The endovascular procedure for carotid artery revascularization and intracranial stent thrombectomy is described. Six patients met inclusion criteria (National Institutes of Health Stroke Scale score 12–24, time from symptom onset 2...
Source: Journal of Clinical Neuroscience - April 29, 2016 Category: Neuroscience Source Type: research
Treatment of patients with mild acute ischemic stroke and associated large vessel occlusion
Publication date: Available online 3 April 2016 Source:Journal of Clinical Neuroscience Author(s): Russell Cerejo, Esteban Cheng-Ching, Ferdinand Hui, M. Shazam Hussain, Ken Uchino, Jennifer Bullen, Gabor Toth Several recent studies have shown that patients presenting with mild acute ischemic stroke (mAIS) symptoms may have an unfavorable natural history. The presence of associated large vessel occlusion (LVO) may lead to even worse outcomes, but most mAIS patients are still excluded from acute stroke treatment (AST). A retrospective review of patients with acute ischemic stroke presenting to our institution betwe...
Source: Journal of Clinical Neuroscience - April 3, 2016 Category: Neuroscience Source Type: research
Direct admission to stroke centers reduces treatment delay and improves clinical outcome after intravenous thrombolysis
Publication date: Available online 9 January 2016 Source:Journal of Clinical Neuroscience Author(s): Dae-Hyun Kim, Hee-Joon Bae, Moon-Ku Han, Beom Joon Kim, Sang-Soon Park, Tai Hwan Park, Kyung Bok Lee, Kyusik Kang, Jong-Moo Park, Youngchai Ko, Soo Joo Lee, Jay Chol Choi, Joon-Tae Kim, Ki-Hyun Cho, Keun-Sik Hong, Yong-Jin Cho, Dong-Eog Kim, Jun Lee, Juneyoung Lee, Mi Sun Oh, Kyung-Ho Yu, Byung-Chul Lee, Hyun-Wook Nah, Jae-Kwan Cha We aimed to examine whether direct access to hospitals offering intravenous thrombolysis is associated with functional outcomes in patients with acute ischemic stroke tr...
Source: Journal of Clinical Neuroscience - January 11, 2016 Category: Neuroscience Source Type: research
