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Source: Journal of Clinical Neuroscience
Condition: Stroke
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Total 325 results found since Jan 2013.
Mirror writing after perimesencephalic subarachnoid haemorrhage
We report a case of a right-handed Caucasian woman who developed mirror writing following a non-aneurysmal, non-traumatic subarachnoid haemorrhage. The patient was unaware of having this phenomenon, and it was detected by clinical staff when the patient was writing a card to a family member. Serial imaging has ruled out a stroke as well as an underlying vascular abnormality. This phenomenon resolved after two months. Whilst there is a body of literature surrounding mirror writing, to our knowledge, this is the first description of mirror writing in the setting of a perimesencephalic subarachnoid haemorrhage.
Source: Journal of Clinical Neuroscience - April 5, 2019 Category: Neuroscience Source Type: research
Fabry’s disease and stroke: Effectiveness of enzyme replacement therapy (ERT) in stroke prevention, a review with meta-analysis
ConclusionOur meta-analysis based on the currently available data showed that ERT for Fabry’s disease has beneficial effect on stroke prevention. Female carriers and atypically affected males could be started on ERT as soon as diagnosis is made. Further studies are warranted to support the role of ERT in stroke prevention.
Source: Journal of Clinical Neuroscience - April 5, 2019 Category: Neuroscience Source Type: research
Intravenous thrombolysis with tissue-plasminogen activator in small vessel occlusion
This study included 2482 patients: 193 in the IV-TPA group and 2289 in the control group. After adjusting covariates, IV-TPA treatment was associated with an increased mRS 0-1 outcome (adjusted OR [95% CI], 1.56 [1.06–2.29]; P = 0.0249), but was not significantly associated with a favorable mRS shift (1.33 [0.98–1.81]; P = 0.0709). SICH and 3-month death occurred in three (1.6%) and none in the IV-TPA group versus one (0.04%) and 16 (0.7%) in the control group. In subgroup analyses, the IV-TPA effect appeared significantly greater in patients aged ≥80 versus <80 for mRS score distribution (Pinteraction ...
Source: Journal of Clinical Neuroscience - April 4, 2019 Category: Neuroscience Source Type: research
Prognostic value of elevated high-sensitivity cardiac troponin T levels in patients with acute ischemic stroke treated with endovascular thrombectomy
Publication date: Available online 28 March 2019Source: Journal of Clinical NeuroscienceAuthor(s): Yue-Zhou Cao, Lin-Bo Zhao, Sheng Liu, Qiang-Hui Liu, Lei Jiang, Chun-Gao Zhou, Zhen-Yu Jia, Wei-Zhong Zhou, Jin-Guo Xia, Wen-Tao Wu, Qing-Quan Zu, Shan-Shan Lu, Xiao-Quan Xu, Hai-Bin ShiAbstractOur objective was to assess the impact of hs-cTnT elevation on functional outcome and mortality in AIS patients with large vessel occlusion (LVO) in the anterior circulation 3 months after ET and explore factors affecting hs-cTnT elevation.A total of 143 consecutive AIS patients with large vessel occlusion (LVO) in the anterior circu...
Source: Journal of Clinical Neuroscience - March 29, 2019 Category: Neuroscience Source Type: research
Recurrent ischemic stroke in atrial fibrillation with non-vitamin K antagonist oral anticoagulation
Publication date: Available online 28 March 2019Source: Journal of Clinical NeuroscienceAuthor(s): Ho Geol Woo, Inyoung Chung, Dong Seok Gwak, Baik Kyun Kim, Beom Joon Kim, Hee-Joon Bae, Moon-Ku HanAbstractThe etiology or rate of recurrent ischemic stroke according to dosing methods including drug adherence in patients taking non-vitamin K antagonist oral anticoagulants (NOACs) remain uncertain. We investigated the association between dosing methods including drug adherence achieved with NOACs and the presence of major vessel occlusion (MVO) in patients with ischemic stroke with non-valvular atrial fibrillation (NVAF). Fro...
Source: Journal of Clinical Neuroscience - March 29, 2019 Category: Neuroscience Source Type: research
Ischemic stroke of the “hand knob area”: A case series and literature review
In conclusion, in this series the most prevalent stroke mechanism was SUE, mainly embolic stroke of undetermined source. The outcome was excellent regardless of stroke mechanism.
Source: Journal of Clinical Neuroscience - March 23, 2019 Category: Neuroscience Source Type: research
Vasospasm as a major complication after acute mechanical thrombectomy with stent retrievers
ConclusionStent retrievers appear to cause vasospasm more than expected when including mild cases. Vasospasm tends to occur especially in cases with IV-tPA; prognosis is generally good, and it rarely requires any treatment.
Source: Journal of Clinical Neuroscience - March 21, 2019 Category: Neuroscience Source Type: research
Extravasation control with preserved vessel patency after wire perforation during neurothrombectomy: Case report and literature review
Publication date: Available online 20 March 2019Source: Journal of Clinical NeuroscienceAuthor(s): Pouria Moshayedi, Shashvat M. Desai, Ashutosh P. JadhavAbstractParallel to a more widespread application of endovascular neurothrombectomy in acute ischemic stroke, it is critical to understand the nature and management of associated complications, including wire perforation of the middle cerebral artery (MCA). Sacrifice of the perforated vessel may be necessary to avoid fatal intra-cranial hemorrhage. Here we describe a case of right MCA distribution ischemia complicated by a right MCA perforation. Using super selective inje...
Source: Journal of Clinical Neuroscience - March 21, 2019 Category: Neuroscience Source Type: research
Beat-to-beat blood pressure variability and heart rate variability in relation to autonomic dysregulation in patients with acute mild-moderate ischemic stroke
Publication date: Available online 12 March 2019Source: Journal of Clinical NeuroscienceAuthor(s): Ge Tian, Li Xiong, Howan Leung, Yannie Soo, Thomas Leung, Lawrence Ka-sing WongAbstractAutonomic dysregulation is common in post-stroke patients. We aimed to correlate beat-to-beat blood pressure variability (BPV) and heart rate variability (HRV) with Ewing’s test classification. We enrolled patients with acute ischemic stroke. Autonomic function was assessed by Ewing battery and dichotomized into minor or significant group. Beat-to-beat blood pressure and heart rate were monitored for calculating the frequency components o...
Source: Journal of Clinical Neuroscience - March 13, 2019 Category: Neuroscience Source Type: research
Guillain-Barré syndrome as a complication of hypertensive basal ganglia haemorrhage
We present a case of a 70-year-old hypertensive woman who developed global weakness, eventually becoming quadriplegic, during an inpatient stay for treatment of a basal ganglia haemorrhagic stroke. Guillain-Barré syndrome was confirmed and treatment initiated. She responded well to intravenous immunoglobulin treatment and then subsequently continued with rehabilitation.There have been a few case reports of GBS as a complication of spontaneous intracranial haemorrhage (ICH) or traumatic brain injury. It may not be a coincidence that our patient developed GBS shortly after presentation. There may be an immunological explana...
Source: Journal of Clinical Neuroscience - March 7, 2019 Category: Neuroscience Source Type: research
Angioplasty and stenting for severe symptomatic atherosclerotic stenosis of intracranial vertebrobasilar artery
Publication date: Available online 6 March 2019Source: Journal of Clinical NeuroscienceAuthor(s): Yu Zhou, Li Wang, Jian-Rong Zhang, Kai Zhou, Jie Shuai, Zi-Li Gong, Yong Liu, Fei Wei, Yu-Fu Han, Lin Shen, Qing-Wu YangAbstractThis retrospective study is to investigate the safety and efficacy of the stent implanting for treating severe symptomatic atherosclerotic stenosis of the intracranial vertebrobasilar artery (ICVBA). 213 patients who had undergone intervention for severe symptomatic ICVBA stenosis between September 2012 to May 2018 were enrolled into this study. Among the 213 enrolled patients, 210 patients (98.6%) ob...
Source: Journal of Clinical Neuroscience - March 6, 2019 Category: Neuroscience Source Type: research
Medical and endovascular treatments of symptomatic intracranial stenosis. A Bayesian network meta-analysis
Publication date: Available online 8 February 2019Source: Journal of Clinical NeuroscienceAuthor(s): S. Vidale, E. Agostoni, G. Grampa, A. Consoli, D. ConsoliAbstractIntracranial stenosis is a well-established stroke risk factor with an increase of stroke recurrence or TIA up to 12.6% at 1 year. Treatments are different: medical and endovascular. We performed a multiple treatment comparison analysis to detect the best treatment in reducing the risk of stroke recurrence. We searched in Medline, Embase, Cochrane Central Register of Controlled Trials databases between 1979 and October 2017. Inclusion criteria were prospecti...
Source: Journal of Clinical Neuroscience - February 9, 2019 Category: Neuroscience Source Type: research
Platelet-to-neutrophil ratio is a prognostic marker for 90-days outcome in acute ischemic stroke
In this study, a total of 400 AIS patients were included. Demographic, clinical, laboratory data were collected on admission, and PNR was calculated according to platelet and neutrophil counts on admission. The prognosis after 3 months was evaluated by the Barthel index (BI), where BI ≤85 was defined as poor prognosis and BI>85 was defined as good prognosis. Regression analyses were performed, adjusting for confounders. (1) Compared with good prognosis group, PNR level on admission in poor prognosis group was significantly lower, the difference between the two groups was statistically significant (P < 0.05). (2...
Source: Journal of Clinical Neuroscience - February 6, 2019 Category: Neuroscience Source Type: research
Asymptomatic moderate carotid artery stenosis with intraplaque hemorrhage: Progression of degree of stenosis and new ischemic stroke
Publication date: Available online 4 February 2019Source: Journal of Clinical NeuroscienceAuthor(s): Kiyofumi Yamada, Shinichi Yoshimura, Manabu Shirakawa, Kazutaka Uchida, Shigehiro Nakahara, Shuji Nishida, Yasuhiro Iwamoto, Yoshikazu Sato, Masanori KawasakiAbstractCarotid intraplaque hemorrhage (IPH) plays a critical role in the progression of carotid atherosclerotic disease. IPH was associated with high intensity signal (HIS) in the plaque on Maximum intensity projection (MIP) images from routine three dimensional magnetic resonance imaging (3D-TOF MRA). The aim of this study was to evaluate the relationships among HIS,...
Source: Journal of Clinical Neuroscience - February 5, 2019 Category: Neuroscience Source Type: research
The different clinical value of susceptibility vessel sign in acute ischemic stroke patients under different interventional therapy: A systematic review and meta-analysis
Publication date: Available online 1 February 2019Source: Journal of Clinical NeuroscienceAuthor(s): Mingsu Liu, Lin Li, Guangqin LiAbstractAcute ischemic stroke (AIS) subtype, one of the most important factors for selecting therapeutic strategies, is difficult to be accurately diagnosed at admission sometimes. The magnetic susceptibility effect of deoxygenated hemoglobin in red thrombi appeared as hypointense signals in magnetic resonance imaging (MRI) scans. The prognostic value of susceptibility vessel sign (SVS) for stroke subtype, recanalization and outcomes in AIS patients will be comprehensively determined in the pr...
Source: Journal of Clinical Neuroscience - February 1, 2019 Category: Neuroscience Source Type: research
