Prognostic value of elevated high-sensitivity cardiac troponin T levels in patients with acute ischemic stroke treated with endovascular thrombectomy

Publication date: Available online 28 March 2019Source: Journal of Clinical NeuroscienceAuthor(s): Yue-Zhou Cao, Lin-Bo Zhao, Sheng Liu, Qiang-Hui Liu, Lei Jiang, Chun-Gao Zhou, Zhen-Yu Jia, Wei-Zhong Zhou, Jin-Guo Xia, Wen-Tao Wu, Qing-Quan Zu, Shan-Shan Lu, Xiao-Quan Xu, Hai-Bin ShiAbstractOur objective was to assess the impact of hs-cTnT elevation on functional outcome and mortality in AIS patients with large vessel occlusion (LVO) in the anterior circulation 3 months after ET and explore factors affecting hs-cTnT elevation.A total of 143 consecutive AIS patients with large vessel occlusion (LVO) in the anterior circulation following ET in a single stroke center were enrolled between January 2015 and November 2017. Hs-cTnT was quantitated on admission. Demographic characteristics, clinical data, functional outcome and all-cause mortality were compared between patients with elevated hs-cTnT levels (>14 ng/L) and those with normal hs-cTnT levels (≤14 ng/L). 58/143(40.6%) patients showed elevated hs-cTnT levels before ET. Factors independently associated with hs-cTnT elevation were admission NIHSS score (OR = 1.08, 95% CI 1.01–1.16, p = 0.032), coronary heart disease (OR = 4.89, 95% CI 1.82–13.11, p = 0.002) and congestive heart failure (OR = 4.10, 95% CI 1.07–15.68, p = 0.039). In the univariate analysis, patients with elevated hs-cTnT levels were at significantly higher risk of 3-month poor outcome (p = 0.029) and mortality (p ...
Source: Journal of Clinical Neuroscience - Category: Neuroscience Source Type: research