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Clinical characteristics and treatment outcomes among stroke patients hospitalized to Nekemte referral hospital, western Ethiopia
ConclusionAbout two third of the patients had poor treatment outcome. Educational status and mean length of hospital stays were independent predictors of poor treatment out-comes. An emergency care setup capable of early patient evaluation, identification and management of stroke complications is crucial to overcome early stroke related mortality.
Source: Journal of Clinical Neuroscience - January 25, 2020 Category: Neuroscience Source Type: research

Epidemiologic features and risk factors of sepsis in ischemic stroke patients admitted to intensive care: A prospective cohort study
ConclusionsThis study showed that ICU patients with severe ischemic stroke were more susceptible to sepsis during the hospital course.
Source: Journal of Clinical Neuroscience - September 20, 2019 Category: Neuroscience Source Type: research

Carotid artery plaque detected on ultrasound is associated with impaired cognitive state in the elderly: A population-based study in Wakiso district, Uganda
This study set out to determine the prevalence of abnormal carotid ultrasound findings and their association with cognitive function among the adults ≥60 years in Wakiso district, Uganda in 2018. A total of 210 participants were included. Carotid artery stenosis, presence of plaque, stenosis and intima-media thickness were assessed by ultrasound. Cognitive status was assessed using a Mini Mental State Exam (MMSE) test. The prevalence of plaque was 21.4%. Variables which included; presence of plaque, age, education, gender, marital status, whether participant stayed alone or with someone else, care for self, occupation ...
Source: Journal of Clinical Neuroscience - July 12, 2019 Category: Neuroscience Source Type: research

Mechanical thrombectomy for recurrent large vessel occlusion
Publication date: Available online 18 May 2019Source: Journal of Clinical NeuroscienceAuthor(s): P. Bhogal, M. AlMatter, V. Hellstern, M. Aguilar Pérez, O. Ganslandt, H. Bäzner, H. HenkesAbstractAlthough mechanical thrombectomy (MT) has been shown in numerous trials to be a successful treatment option for patients with large vessel occlusion (LVO), there is limited information on the safety and effectiveness of the technique in cases of recurrent LVO. To this end, we performed a retrospective review of our prospectively maintained database to identify all patients that had undergone more than one MT procedure January 200...
Source: Journal of Clinical Neuroscience - May 19, 2019 Category: Neuroscience Source Type: research

Correlation between pre-admission blood pressure and outcome in a large telestroke cohort
ConclusionsThis study displays better clinical outcomes at latest follow-up when compared to current international TS studies. SBP during transportation to the hub hospital did not prove to be a useful prognostic metric. However, future studies should address the limitations of this study to confirm these findings.
Source: Journal of Clinical Neuroscience - January 17, 2019 Category: Neuroscience Source Type: research

Impact of risk factors for recurrence after the first ischemic stroke in adults: A systematic review and meta-analysis
Publication date: Available online 16 October 2018Source: Journal of Clinical NeuroscienceAuthor(s): Shengbang Zheng, Baodong YaoAbstractRisk factors for first-ever stroke have been studied extensively, while those for recurrent stroke are not accurately understood. To provide the adequate secondary prevention for the patients, it is necessary to reveal the risk factors that dominate recurrent stroke. Multiple databases were adopted to search for the relevant studies and full-text articles involving in the risk factors for stroke recurrence were reviewed. Meta-analyses were performed with Review Manager 5.0 to estimate the...
Source: Journal of Clinical Neuroscience - October 17, 2018 Category: Neuroscience Source Type: research

Impact of small vessel disease on severity of motor and cognitive impairment in Parkinson’s disease
ConclusionsThis study demonstrates an association between SVD and motor impairment, and between vascular risk factors, particularly hypertension, and dementia in PD and highlights the need to manage vascular co-morbidities in PD patients.
Source: Journal of Clinical Neuroscience - October 14, 2018 Category: Neuroscience Source Type: research

The current role of decompressive craniectomy for severe traumatic brain injury
Publication date: September 2017 Source:Journal of Clinical Neuroscience, Volume 43 Author(s): S. Honeybul, K.M. Ho, C.R.P. Lind, G.R. Gillett There is little doubt that decompressive craniectomy can reduce mortality however, the results of a recent study has provided more evidence to inform the debate regarding clinical and ethical concerns that it merely converts death into survival with severe disability or in a vegetative state. The recently published RESCUEicp trial compared last-tier secondary decompressive craniectomy with continued medical management for refractory intracranial hypertension after severe traumatic ...
Source: Journal of Clinical Neuroscience - August 1, 2017 Category: Neuroscience Source Type: research

Clinical and radiological assessment of cerebral hemodynamics after cranioplasty for decompressive craniectomy – A Clinical study
Conclusion Cranioplasty influences the cerebral hemodynamics after cranioplasty and has a positive correlation on the functional outcome and cerebral blood flow in the MCA territory.
Source: Journal of Clinical Neuroscience - June 29, 2017 Category: Neuroscience Source Type: research

Prognostic value of peripheral leukocyte counts and plasma glucose in intracerebral haemorrhage
Conclusion These results suggest that a logistic regression model using low admission glucose and low total leukocyte count may be markers of better prognosis in acute haemorrhagic stroke with a differential effect between sexes.
Source: Journal of Clinical Neuroscience - June 12, 2017 Category: Neuroscience Source Type: research

Changing paradigm in the management of elderly patients with intracranial aneurysms: An institutional review
Publication date: Available online 7 June 2017 Source:Journal of Clinical Neuroscience Author(s): Oleg Y. Chernyshev, Shyamal C. Bir, Tanmoy K. Maiti, Devi Prasad Patra, Cesar Liendo, Hugo Cuellar, Alireza Minagar, Anil Nanda Optimal treatment of intracranial aneurysms (IAs) in elderly patients has not yet been well established. We have investigated the clinical and radiological outcomes and predictors of unfavorable outcome of IAs in elderly patients. Radiological and clinical data of 85 elderly patients from 2010 through 2015 were retrospectively reviewed. Significant differences between the groups were determined by a ...
Source: Journal of Clinical Neuroscience - June 7, 2017 Category: Neuroscience Source Type: research

Clinical predictors for favorable outcomes from endovascular recanalization in wake-up stroke
Conclusions The results of this study suggest that the SRDT is an independent predictor of both an improvement of NIHSS score and a good functional outcome in endovascular recanalization for WUS patients.
Source: Journal of Clinical Neuroscience - March 1, 2017 Category: Neuroscience Source Type: research

Pituitary aspergillus infection
We report a case of Aspergillus infection involving the pituitary gland and sellar region discovered in a 74-year-old man. The patient had a history of hypertension, chronic renal disease, autoimmune hemolytic anemia and presented with right eye pain, headaches and worsening hemiparesis. Imaging studies revealed a right internal carotid artery occlusion and an acute right pontine stroke along with smaller infarcts in the right middle cerebral artery distribution. Clinically, the patient was thought to have vasculitis. An infectious etiology was not identified. He developed respiratory distress and died. At autopsy, necroti...
Source: Journal of Clinical Neuroscience - May 29, 2016 Category: Neuroscience Source Type: research