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Source: Journal of Clinical Neuroscience
Condition: Ischemic Stroke
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Total 164 results found since Jan 2013.
Vertebrobasilar dolichoectasia presenting simultaneously with ischemic and hemorrhagic strokes
ConclusionThe perforating vessels branching off of the pathologic VBDE may result in both ischemia and hemorrhage. This is the first known case, to our knowledge, in which hemorrhage and cerebral ischemia occurred simultaneously.
Source: Journal of Clinical Neuroscience - November 12, 2018 Category: Neuroscience Source Type: research
Risk factors for ischemic stroke post bone fracture
Publication date: Available online 7 November 2018Source: Journal of Clinical NeuroscienceAuthor(s): Qi An, Zhe Chen, Kang Huo, Hua Su, Qiu-Min QuAbstractStroke is one of the most devastating complications after bone fracture. However, due to the rarity of the complication, the risk factor for post fracture stroke remains unknown. We retrospectively reviewed 2914 fractured adults referred to the first affiliated hospital of Xi’an Jiaotong University, a regional referral center of China, from January 2008 to May 2013. As a result, among the 2914 patients, 13 of them had newly onset stroke within a median of 4 days after...
Source: Journal of Clinical Neuroscience - November 8, 2018 Category: Neuroscience Source Type: research
Thrombectomy in stroke of unknown onset, wake up stroke and late presentations: Australian experience from 2 comprehensive stroke centres
This study shows good ‘real world’ outcomes, comparable to published RCTs, in patients with unknown-onset, or late presentation, stroke treated with EVT more than 6 h from stroke onset.
Source: Journal of Clinical Neuroscience - November 8, 2018 Category: Neuroscience Source Type: research
Efficacy and safety of drug-eluting stent for the intracranial atherosclerotic disease: A systematic review and meta-analysis
Publication date: Available online 3 November 2018Source: Journal of Clinical NeuroscienceAuthor(s): Gengfan Ye, Xiaoliang Yin, Ximeng Yang, Junjie Wang, Peng Qi, Jun Lu, Lijun Wang, Daming WangAbstractDrug-eluting stent (DES) is a potential endovascular treatment for patients with symptomatic intracranial atherosclerotic disease (sICAD). However, evidence regarding the treatment of ICAD with DES is lacking. We systematically searched Pubmed, Embase, Cochrane database (before 2017-12-21) for literature reporting the application of DES in the treatment of sICAD. The main outcomes were as follows: the incidence of any stroke...
Source: Journal of Clinical Neuroscience - November 4, 2018 Category: Neuroscience Source Type: research
Iron nanoparticle contrast enhanced microwave imaging for emergent stroke: A pilot study
Publication date: Available online 1 November 2018Source: Journal of Clinical NeuroscienceAuthor(s): Joseph S. Hudson, Timothy K. Chung, Benjamin S. Prout, Yasunori Nagahama, Madhavan L. Raghavan, David M. HasanAbstractEmergent stroke is mostly evaluated using hospital based imaging. Quick imaging allows for rapid administration of IV thrombolysis and outcome improvement. Microwave imaging (MI) is an emerging portable imaging modality. Iron oxide nanoparticles are known to interact with microwave frequency electromagnetic radiation. In this manuscript, we provide proof of concept for a novel iron oxide nanoparticle enhance...
Source: Journal of Clinical Neuroscience - November 2, 2018 Category: Neuroscience Source Type: research
Post-thrombolysis rupture of small lenticulostriate aneurysms: A report of 2 consecutive cases
This report suggests that LSA aneurysms, regardless of size, be considered separately from other conventional aneurysms as “high-risk” lesions and a contraindication to thrombolysis.
Source: Journal of Clinical Neuroscience - October 25, 2018 Category: Neuroscience Source Type: research
2016–2017 clinical trials in cerebrovascular neurosurgery
Publication date: Available online 24 October 2018Source: Journal of Clinical NeuroscienceAuthor(s): Wendy Huang, Rose DuAbstractSeveral clinical trials in cerebrovascular neurosurgery were published during 2016–2017. The Collaborative Unruptured Endovascular versus Surgery Trial (CURES) found no difference in outcome between clipping versus coiling of unruptured aneurysms after one year. The Flow Diversion in the Treatment of Intracranial Aneurysm Trial (FIAT) was terminated due to safety concerns. Nimodipine Microparticles to Enhance Recovery While Reducing Toxicity after Subarachnoid Hemorrhage Trial (NEWTON) and othe...
Source: Journal of Clinical Neuroscience - October 25, 2018 Category: Neuroscience Source Type: research
Emergency medical services for acute ischemic stroke: Hub-and-spoke model versus exclusive care in comprehensive centers
ConclusionsUsing a comprehensive all-payer cohort of acute ischemic stroke patients in New York State we demonstrated that patients treated in a hub-and-spoke model were not associated with worse outcomes than patients receiving care exclusively in comprehensive institutions. This needs to be taken into consideration when considering acute emergency services in this setting.
Source: Journal of Clinical Neuroscience - October 20, 2018 Category: Neuroscience Source Type: research
Impact of risk factors for recurrence after the first ischemic stroke in adults: A systematic review and meta-analysis
Publication date: Available online 16 October 2018Source: Journal of Clinical NeuroscienceAuthor(s): Shengbang Zheng, Baodong YaoAbstractRisk factors for first-ever stroke have been studied extensively, while those for recurrent stroke are not accurately understood. To provide the adequate secondary prevention for the patients, it is necessary to reveal the risk factors that dominate recurrent stroke. Multiple databases were adopted to search for the relevant studies and full-text articles involving in the risk factors for stroke recurrence were reviewed. Meta-analyses were performed with Review Manager 5.0 to estimate the...
Source: Journal of Clinical Neuroscience - October 17, 2018 Category: Neuroscience Source Type: research
Acute reversal of dabigatran with Idarucizumab for intravenous thrombolysis as acute stroke treatment
We describe the case of a 73 year old male with AIS and active dabigatran use. Idarucizumab was administered per an approved medical center protocol and the patient was subsequently treated with IV rt-PA. The patient had a severe stroke with no other contraindications to IV rt-PA other than dabigatran use. The patient was administered Idarucizumab and IV rt-PA was given. Within 24 h of treatment, the patient had minimal stroke deficits. Imaging revealed a right middle cerebral artery patchy infarct. The patient was restarted on dabigatran therapy for his atrial fibrillation and was discharged to a skilled nursing facil...
Source: Journal of Clinical Neuroscience - October 9, 2018 Category: Neuroscience Source Type: research
Predictive value of plasma matrix metalloproteinase-9 concentrations for spontaneous haemorrhagic transformation in patients with acute ischaemic stroke: A cohort study in Chinese patients
Publication date: Available online 2 October 2018Source: Journal of Clinical NeuroscienceAuthor(s): Ruozhen Yuan, Song Tan, Deren Wang, Simiao Wu, Xinhui Cao, Shihong Zhang, Bo Wu, Ming LiuAbstractWhether matrix metalloproteinase 9 (MMP-9) concentrations in plasma predict risk of spontaneous haemorrhagic transformation (sHT) in acute ischaemic stroke is unclear. From 1 March 2003 to 27 February 2006, patients with acute ischaemic stroke admitted to West China Hospital within 24 h of onset and healthy controls were enrolled and blood samples obtained. Plasma MMP-9 concentrations were determined using enzyme-linked immunos...
Source: Journal of Clinical Neuroscience - October 4, 2018 Category: Neuroscience Source Type: research
Comparison of magnetic resonance spectroscopy (MRS) with arterial spin labeling (ASL) in the differentiation between mitochondrial encephalomyopathy, lactic Acidosis, plus stroke-like episodes (MELAS) and acute ischemic stroke (AIS)
Publication date: September 2018Source: Journal of Clinical Neuroscience, Volume 55Author(s): Xiaodi Li, Yuzhou Wang, Zhanhang Wang, Jianjun Lu, Yan Xu, Jinlong Ye, Zuying Kuang, Bo Li, Mengqiu Pan, Wenming Chen, Shuisheng Lu, Ziyang Zhou, Lina Cheng, Honghao WangAbstractTo compare the utility and limitation of magnetic resonance spectroscopy (MRS) and arterial spin labeling (ASL) in the differentiation between mitochondrial encephalomyopathy, lactic acidosis, plus stroke-like episodes (MELAS) and acute ischemic stroke (AIS), a retrospective review of 17 MELAS and 26 AIS patients were performed. In all patients both MRS an...
Source: Journal of Clinical Neuroscience - October 4, 2018 Category: Neuroscience Source Type: research
Association of serum lipids with clinical outcome in acute ischaemic stroke: A systematic review and meta-analysis
This study aimed at assessing the association between serum lipid and clinical outcomes in acute ischaemic stroke. Relevant data were obtained from Cochrane Library, PubMed and Web of Science databases. The heterogeneity of pooled results was determined by the Cochran’s Q test and Higgins I-squared statistic. The random-effect model was performed to calculate the pooled results if PH < 0.05 for Q-test, otherwise the fixed-effect model was applied. The primary results were death, and the secondary were recurrence, dependency, mRS score ≥3, and early neurological deterioration. A total of 21 full-text studies was...
Source: Journal of Clinical Neuroscience - September 20, 2018 Category: Neuroscience Source Type: research
Ability of the Khorana score to predict recurrent thromboembolism in cancer patients with ischemic stroke
In this study, the Khorana score had poor discriminatory ability for predicting RTE in cancer patients with AIS. Future research is needed to identify better methods for predicting RTE in this high-risk population.
Source: Journal of Clinical Neuroscience - August 23, 2018 Category: Neuroscience Source Type: research
Predictors of 30-day mortality after endovascular mechanical thrombectomy for acute ischemic stroke
ConclusionWe observed a moderate rate of 30-day mortality after EMT at an academic CSC. Older age, higher baseline NIHSS score, higher NIHSS score at 24 h after thrombectomy, and lower rates of successful revascularization were predictive of 30-day mortality in univariate analysis. Further efforts to identify modifiable risk factors of mortality are warranted.
Source: Journal of Clinical Neuroscience - August 23, 2018 Category: Neuroscience Source Type: research
