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Source: Journal of Clinical Neuroscience
Condition: Ischemic Stroke

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Total 164 results found since Jan 2013.

Early partial recanalization after intravenous thrombolysis leads to prediction of favorable outcome in cases of acute ischemic stroke with major vessel occlusion
Publication date: December 2017 Source:Journal of Clinical Neuroscience, Volume 46 Author(s): Jun Young Chang, Hyun Park, Se Young Jang, Seunguk Jung, Hee-Joon Bae, O-Ki Kwon, Moon-Ku Han We investigated the association between early recanalization degree after intravenous thrombolysis (IVT), occurrence of hemorrhagic transformation, and functional outcome. We also evaluated whether recombinant tissue plasminogen activator (rTPA) dosing error could influence the outcome. Patients with ischemic stroke with major vessel occlusion (n=256) who underwent IVT were included. Recanalization status (no recanalization, partial reca...
Source: Journal of Clinical Neuroscience - October 27, 2017 Category: Neuroscience Source Type: research

Clinical characteristics of patients with ischemic stroke following the 2016 Kumamoto earthquake
Publication date: December 2017 Source:Journal of Clinical Neuroscience, Volume 46 Author(s): Yuichiro Inatomi, Makoto Nakajima, Toshiro Yonehara, Yukio Ando To investigate the clinical characteristics of patients with ischemic stroke following the 2016 Kumamoto earthquake. We retrospectively studied patients with ischemic stroke admitted to our hospital for 12weeks following the earthquake. We compared the clinical backgrounds and characteristics of the patients: before (the same period from the previous 3years) and after the earthquake; and the early (first 2weeks) and late (subsequent 10weeks) phases. A total of 194 pa...
Source: Journal of Clinical Neuroscience - October 27, 2017 Category: Neuroscience Source Type: research

High prevalence of small vessel disease long after cranial irradiation
In conclusion, small vessel disease is not a rare complication after cranial irradiation, even in young patients. Patients after cranial irradiation should be followed up with MR imaging including a hemosiderin-sensitive sequence.
Source: Journal of Clinical Neuroscience - October 27, 2017 Category: Neuroscience Source Type: research

Endovascular treatment of acute tandem occlusion strokes and stenting first experience
This study demonstrates the radiologic and clinical findings, etiologies and intervention strategy in 8 acute ischemic stroke patients with tandem occlusions. The mean age was 57 and mean NIHSS score was 19. Stent-assisted thrombectomy (SAT) was performed on all of the patients. Additionally, 6 patients underwent carotid artery stenting before SAT. Recanalization with TICI≥2b was attained in 7/8 patients. The 90thday median mRS was 2 and mortality was 1/8. The etiologies of the tandem occlusions were either extracranial high grade ICA stenosis/occlusion or cervical ICA dissection. When the stent-first approach was applie...
Source: Journal of Clinical Neuroscience - October 9, 2017 Category: Neuroscience Source Type: research

Factors associated with early dramatic recovery following successful recanalization of occluded artery by endovascular treatment in anterior circulation stroke
Publication date: Available online 3 October 2017 Source:Journal of Clinical Neuroscience Author(s): Dae-Hyun Kim, Hyun-Wook Nah, Hyun-Seok Park, Jae-Hyung Choi, Myung-Jin Kang, Jae-Kwan Cha Endovascular treatment (EVT) significantly increases the recanalization rate and improves functional outcomes in acute ischemic stroke. However, despite successful recanalization by EVT, some stroke patients demonstrate no early dramatic recovery (EDR). We assessed factors associated with EDR following recanalization by EVT. We included subjects with anterior circulation stroke treated with EVT who met the following criteria: Thrombol...
Source: Journal of Clinical Neuroscience - October 3, 2017 Category: Neuroscience Source Type: research

Access disparities to Magnet hospitals for ischemic stroke patients
We examined the association of African–American race with Magnet status hospitalization after ischemic stroke. A mixed effects propensity adjusted multivariable regression analysis was used to control for confounding. During the study period, 176,557 patients presented with ischemic stroke, and met the inclusion criteria. Overall, 4,624 (13.7%) African-Americans, and 27,468 (19.2%) non African-Americans with ischemic stroke were admitted to Magnet hospitals. Using a multivariable logistic regression, we demonstrate that African-Americans were associated with lower admission rates to Magnet institutions (OR 0.70; 95% CI, ...
Source: Journal of Clinical Neuroscience - August 1, 2017 Category: Neuroscience Source Type: research

Isolated intracranial fibromuscular dysplasia of the posterior cerebral artery
We report a patient with FMD involving the posterior cerebral arteries (PCAs). A 24year old female was presented with a 4day history of right homonymous hemianopsia with throbbing headache in the left temporo-occipital area. The brain magnetic resonance imaging (MRI) revealed an acute ischemic stroke in the left PCA territory, while the Time of Flight (TOF) magnetic resonance angiogram (MRA) showed segmental luminal irregularities in the left proximal PCA. The conventional angiogram revealed the “string of beads” appearance, a characteristic that is pathognomonic for FMD. The patient’s inhospital clinical course was ...
Source: Journal of Clinical Neuroscience - August 1, 2017 Category: Neuroscience Source Type: research

Association between nocturnal blood pressure variation and wake-up ischemic stroke
In this study, we used ambulatory blood pressure monitoring (ABPM) to examine the association between WUS and variation in nocturnal BP. A total of 369 patients with ischemic stroke within one week were consecutively enrolled. ABPM was applied 1–2weeks after the ictus because of possible reactive increments of BP; antihypertensive medications were delayed until ABPM. Patients were classified into two groups: WUS and non-WUS. Clinical characteristics, including ABPM parameters, were compared. Sixty-seven (18%) patients had WUS. In univariate analysis, patients with WUS had more severe stroke symptoms than patients with no...
Source: Journal of Clinical Neuroscience - July 20, 2017 Category: Neuroscience Source Type: research

Stroke prediction with CHA2DS2-VASc score in patients with mesenteric ischemia without atrial fibrillation-insights from a nationwide cohort
Conclusions A higher CHA2DS2-VASc score is demonstrated to be associated with an increased risk of ischemic stroke among patients with mesenteric ischemia without comorbid AF.
Source: Journal of Clinical Neuroscience - July 3, 2017 Category: Neuroscience Source Type: research

Association of ischemic and hemorrhagic strokes hospital admission with extreme temperature in Nanchang, China —A case-crossover study
This study suggests that extreme high temperature might be a risk factor for both hemorrhagic and ischemic strokes, and that extreme low temperature might be a risk factor of hemorrhagic stroke. Further studies are necessary in order to clarify this relationship and provide evidence for stroke prevention.
Source: Journal of Clinical Neuroscience - June 17, 2017 Category: Neuroscience Source Type: research

Prognostic value of peripheral leukocyte counts and plasma glucose in intracerebral haemorrhage
Conclusion These results suggest that a logistic regression model using low admission glucose and low total leukocyte count may be markers of better prognosis in acute haemorrhagic stroke with a differential effect between sexes.
Source: Journal of Clinical Neuroscience - June 12, 2017 Category: Neuroscience Source Type: research

Chronic kidney disease is independently associated with acute recurrent cerebral infarct in patients with atrial fibrillation
Conclusions We found that RCI frequently develops about 5days after admission in patients with AIS and AF and that chronic kidney disease is independently associated with RCI.
Source: Journal of Clinical Neuroscience - March 8, 2017 Category: Neuroscience Source Type: research

Metabolic syndrome and stroke: A meta-analysis of prospective cohort studies
Conclusions This meta-analysis suggests that metabolic syndrome might be an important risk factor of stroke, particularly among women and those with ischemic stroke.
Source: Journal of Clinical Neuroscience - March 7, 2017 Category: Neuroscience Source Type: research

Evaluation of the role of susceptibility-weighted imaging in thrombolytic therapy for acute ischemic stroke
Publication date: Available online 20 February 2017 Source:Journal of Clinical Neuroscience Author(s): Guangjian Zhao, Ling Sun, Ziran Wang, Liquan Wang, Zhongrong Cheng, Hongyan Lei, Daiqun Yang, Yansen Cui, Shirui Zhang We inspected low-intensity venous signals and microbleeds in patients with acute ischemic stroke (AIS) using susceptibility-weighted imaging (SWI) before and after administration of within-thrombolytic-time-window thrombolytic therapies, and observed their prognosis and safety, in order to guide individualized thrombolytic therapies. Patients with AIS were divided into groups A or B according to the pres...
Source: Journal of Clinical Neuroscience - February 20, 2017 Category: Neuroscience Source Type: research

Pharmacologic cardioversion with intravenous amiodarone is likely safe in neurocritically Ill patients
Publication date: Available online 13 February 2017 Source:Journal of Clinical Neuroscience Author(s): Michael Su, David Seki, Asma M. Moheet Neurological injury is often associated with cardiac abnormalities, including electrophysiological issues. Cardioversion of acute atrial fibrillation (<48h’ duration) without anticoagulation carries about a 0.7% risk of thromboembolism. There is limited data on managing acute atrial fibrillation specifically in the neuroscience intensive care unit (NSICU) setting. We sought to determine the safety of using intravenous (IV) amiodarone for restoring sinus rhythm in patients w...
Source: Journal of Clinical Neuroscience - February 13, 2017 Category: Neuroscience Source Type: research