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A Study of Convulsive Status Epilepticus Cases in Indonesia
Publication date: Available online 14 March 2019Source: Epilepsy & Behavior Case ReportsAuthor(s): Machlusil Husna, K. Shahdevi Nandar, Risma Karlina Prabawati, Siti NurlaelaAbstractStatus epilepticus (SE) is a serious health issue in developing countries, with high morbidity and mortality rates of 3%–46%. There are two types of SE, convulsive status epilepticus (CSE) and non-convulsive status epilepticus. The most common type, CSE, is easy to detect but, in several cases, the patients are diagnosed too late to be properly treated and hospitalized. The present study therefore investigated the clinical manifestations of C...
Source: Epilepsy and Behavior Case Reports - March 16, 2019 Category: Neurology Source Type: research

PERAMPANEL: A therapeutic alternative in refractory status epilepticus associated with MELAS syndrome
We present three cases of patients with refractory SE associated with MELAS syndrome who responded favorably to PER.All cases were diagnosed as non-convulsive SE (focal without impairment of level of consciousness). After an initial treatment with other antiepileptic drugs, PER was added in all cases (8, 16 and 12 mg) and cessation of SE was observed within the next hours. All the cases showed a stroke-like lesion in MRI.PER may be an effective option in SE associated with MELAS syndrome.
Source: Epilepsy and Behavior Case Reports - February 8, 2019 Category: Neurology Source Type: research

Visual hallucinations: A novel complication after hemispherectomy
Publication date: 2018Source: Epilepsy & Behavior Case Reports, Volume 9Author(s): Jonas Vanags, Monisha Sachdev, Gerald Grant, Mohamad A. MikatiAbstractTwo patients at our center experienced florid visual hallucinations following hemispherectomy. The first patient had drug-resistant left hemispheric focal seizures at 20 months of age from a previous stroke. Following functional hemispherectomy at age 3, he experienced frightening hallucinations 1 month post-operatively lasting 3.5 months. Our second patient underwent subtotal hemispherectomy at age 6 for drug-resistant focal seizures from right hemispheric ...
Source: Epilepsy and Behavior Case Reports - July 10, 2018 Category: Neurology Source Type: research

Visual Hallucinations: A Novel Complication After Hemispherectomy
Publication date: Available online 2 October 2017 Source:Epilepsy & Behavior Case Reports Author(s): Jonas Vanags, Monisha Sachdev, Gerald Grant, Mohamad A. Mikati Two patients at our center experienced florid visual hallucinations following hemispherectomy. Case 1 had intractable left hemisphere focal seizures at 20months of age from a previous stroke. Following functional hemispherectomy at age 3, he experienced frightening hallucinations 1month post-operatively for 3.5months. Case 2 underwent subtotal hemispherectomy at age 6 for intractable focal seizures from right hemisphere cortical dysplasia. 18months late...
Source: Epilepsy and Behavior Case Reports - October 4, 2017 Category: Neurology Source Type: research

Recurrent status epilepticus as the primary neurological manifestation of CADASIL: A case report
Publication date: 2015 Source:Epilepsy & Behavior Case Reports, Volume 3 Author(s): Naim Haddad , Catherine Ikard , Kim Hiatt , Vignesh Shanmugam , James Schmidley Cerebral autosomal dominant arteriopathy with subcortical infarcts and leukoencephalopathy (CADASIL) often presents with a history of migraine with aura and eventual manifestations of dementia with unrelenting, repeated cerebral vascular insults. Only 6–10% of patients with CADASIL have been reported to develop seizures, and status epilepticus (SE) is exceedingly rare. Here, we describe a patient who presented with recurrent SE, with eventual biopsy ...
Source: Epilepsy and Behavior Case Reports - April 2, 2015 Category: Neurology Source Type: research

Young woman with a four-year history of epilepsy and progressive focal cortical atrophy — What is the diagnosis?
We report the case of a young woman with a four-year history of epilepsy that progressed rapidly as evidenced by the development of progressive focal cortical atrophy. She underwent biopsy that showed perinatal ischemia and a prominent inflammatory response, including T-cell infiltration and microglial activation. There was no consensus reached on the final diagnosis although the hypothesis of dual pathology (adult variant of Rasmussen's encephalitis and perinatal stroke) was considered. The possible role of inflammation in the progression of epilepsy caused by a “static” lesion (perinatal stroke) is discussed.
Source: Epilepsy and Behavior Case Reports - November 1, 2014 Category: Neurology Source Type: research