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Incremental value of enhanced plaque length for identifying intracranial atherosclerotic culprit plaques: a high-resolution magnetic resonance imaging study
ConclusionsEnhanced length longer than the plaque length and grade II enhancement were independently associated with culprit plaques. The combination of the enhanced plaque features resulted in better culprit plaque identification.
Source: Insights into Imaging - May 25, 2023 Category: Radiology Source Type: research

A clinical –radiomics model based on noncontrast computed tomography to predict hemorrhagic transformation after stroke by machine learning: a multicenter study
ConclusionThe proposed clinical –radiomics model is a dependable approach that could provide risk assessment of HT for patients who receive IVT after stroke.
Source: Insights into Imaging - March 29, 2023 Category: Radiology Source Type: research

Agreement between estimated computed tomography perfusion ischemic core and follow-up infarct on diffusion-weighted imaging
ConclusionsIn patients with successful reperfusion after EVT, CTP-estimated ischemic core showed moderate volumetric and spatial agreement with the follow-up infarct lesion on DWI, similar to the most used commercially available CTP software packages. Severe ischemic core overestimation was relatively uncommon.
Source: Insights into Imaging - December 13, 2022 Category: Radiology Source Type: research

Improving the diagnosis of acute ischemic stroke on non-contrast CT using deep learning: a multicenter study
ConclusionsWith the assistance of our proposed DL model, radiologists got better performance in the detection of AIS lesions on NCCT.
Source: Insights into Imaging - December 6, 2022 Category: Radiology Source Type: research

Cost-effectiveness of artificial intelligence aided vessel occlusion detection in acute stroke: an early health technology assessment
ConclusionsAI tools for LVO detection in emergency care have the potential to improve healthcare outcomes and save costs. We demonstrate how early HTA may be applied for the evaluation of clinically applied AI software for radiology.
Source: Insights into Imaging - September 25, 2021 Category: Radiology Source Type: research

Mapping the ischemic penumbra and predicting stroke progression in acute ischemic stroke: the overlooked role of susceptibility weighted imaging
ConclusionA positive DWI-SWI mismatch is an indicator of the ischemic penumbra and a predictor of infarct expansion if left untreated.
Source: Insights into Imaging - January 12, 2020 Category: Radiology Source Type: research

Diagnostic value of  alternative techniques to gadolinium-based contrast agents in MR neuroimaging—a comprehensive overview
AbstractGadolinium-based contrast agents (GBCAs) increase lesion detection and improve disease characterization for many cerebral pathologies investigated with MRI. These agents, introduced in the late 1980s, are in wide use today. However, some non-ionic linear GBCAs have been associated with the development of nephrogenic systemic fibrosis in patients with kidney failure. Gadolinium deposition has also been found in deep brain structures, although it is of unclear clinical relevance. Hence, new guidelines from the International Society for Magnetic Resonance in Medicine advocate cautious use of GBCA in clinical and resea...
Source: Insights into Imaging - August 22, 2019 Category: Radiology Source Type: research

Current concepts in imaging and endovascular treatment of acute ischemic stroke: implications for the clinician
AbstractDuring the last decade, the management of acute ischemic stroke has changed dramatically, from an expectant bedside “wait and see” attitude towards active treatment, thanks to the continuous improvement of new therapeutic options. In addition to the use of intravenous (IV) thrombolysis in emergent large vessel occlusion (ELVO), endovascular therapy (EVT) has proven to be very efficient in selected acute strok e patients. The indications for EVT have progressed from the era of thrombolysis to individual patient profiling. Recently, several indication parameters, e.g., “treatment time window” or “more dista...
Source: Insights into Imaging - June 12, 2019 Category: Radiology Source Type: research

Magnetic resonance imaging of arterial stroke mimics: a pictorial review
AbstractAcute ischaemic stroke represents the most common cause of new sudden neurological deficit, but other diseases mimicking stroke happen in about one-third of the cases. Magnetic resonance imaging (MRI) is the best technique to identify those ‘stroke mimics’. In this article, we propose a diagnostic approach of those stroke mimics on MRI according to an algorithm based on diffusion-weighted imaging (DWI), which can be abnormal or normal, followed by the results of other common additional MRI sequences, such as T2 with gradient recall ed echo weighted imaging (T2-GRE) and fluid-attenuated inversion recovery (FLAIR...
Source: Insights into Imaging - June 22, 2018 Category: Radiology Source Type: research

Beyond the embolus: “do not miss” diffusion abnormalities of ischaemic and non-ischaemic neurological disease
AbstractGiven the rapid evolution and technological advances in the diagnosis and treatment of acute ischaemic stroke (AIS), including the proliferation of comprehensive stroke centres and increasing emphasis on interventional stroke therapies, the need for prompt recognition of stroke due to acute large vessel occlusion has received significant attention in the recent literature. Diffusion-weighted imaging (DWI) is the gold standard for the diagnosis of acute ischaemic stroke, as images appear positive within minutes of ischaemic injury, and a high signal-to-noise ratio enables even punctate infarcts to be readily detecte...
Source: Insights into Imaging - October 6, 2017 Category: Radiology Source Type: research

ASL and susceptibility-weighted imaging contribution to the management of acute ischaemic stroke
AbstractMagnetic resonance imaging (MRI) plays a central role in the early diagnosis of cerebral vascular events. Today, MRI is used not only for the detection of acute ischaemic lesions, but also to fine tune the diagnosis and improve patient selection for early therapeutic decision-making. In this perspective, new tools such as arterial spin labelling (ASL) and susceptibility-weighted imaging (SWI) sequences have been developed. These MRI sequences enable noninvasive assessment of brain damage, providing important diagnostic and prognostic information: evaluation of cerebral parenchymal perfusion; detection and aetiologi...
Source: Insights into Imaging - November 6, 2016 Category: Radiology Source Type: research