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Prognostic Implications of Left Ventricular Dyssynchrony for Major Adverse Cardiovascular Events in Asymptomatic Women and Men: The Multi-Ethnic Study of Atherosclerosis Heart Failure
Conclusions In an asymptomatic cohort, greater LV dyssynchrony determined by cardiac magnetic resonance imaging predicts adverse cardiovascular outcome in women but not in men. Clinical Trial Registration URL: http://clinicaltrials.gov. Unique identifier: NCT00005487.
Source: JAHA:Journal of the American Heart Association - August 4, 2014 Category: Cardiology Authors: Sharma, R. K., Volpe, G., Rosen, B. D., Ambale-Venkatesh, B., Donekal, S., Fernandes, V., Wu, C. O., Carr, J., Bluemke, D. A., Lima, J. A. C. Tags: Heart Failure Source Type: research

Clinical and Magnetic Resonance Imaging Predictors of Very Early Neurological Response to Intravenous Thrombolysis in Patients With Middle Cerebral Artery Occlusion Stroke
Conclusions Lack of VENI provides an early estimate of 3-month outcome and recanalization after IV-tPA. Baseline NIHSS, onset to treatment time, and diffusion weighted imaging—Alberta Stroke Programme Early CT Score could help to predict lack of VENI and, in turn, might help early selection of candidates for complementary reperfusion strategies.
Source: JAHA:Journal of the American Heart Association - December 5, 2013 Category: Cardiology Authors: Apoil, M., Turc, G., Tisserand, M., Calvet, D., Naggara, O., Domigo, V., Baron, J.-C., Oppenheim, C., Touze, E. Tags: Stroke Source Type: research

Clinical and Magnetic Resonance Imaging Predictors of Very Early Neurological Response to Intravenous Thrombolysis in Patients With Middle Cerebral Artery Occlusion Cardiovascular Surgery
Conclusions Lack of VENI provides an early estimate of 3-month outcome and recanalization after IV-tPA. Baseline NIHSS, onset to treatment time, and diffusion weighted imaging—Alberta Stroke Programme Early CT Score could help to predict lack of VENI and, in turn, might help early selection of candidates for complementary reperfusion strategies.
Source: JAHA:Journal of the American Heart Association - December 5, 2013 Category: Cardiology Authors: Apoil, M., Turc, G., Tisserand, M., Calvet, D., Naggara, O., Domigo, V., Baron, J.-C., Oppenheim, C., Touze, E. Tags: Cardiovascular Surgery Source Type: research

Circulating Omega-3 Polyunsaturated Fatty Acids and Subclinical Brain Abnormalities on MRI in Older Adults: The Cardiovascular Health Study Stroke
Conclusions Among older adults, higher phospholipid long-chain omega-3 PUFA content was associated with lower prevalence of subclinical infarcts and better white matter grade on MRI. Our results support the beneficial effects of fish consumption, the major source of long-chain omega-3 PUFAs, on brain health in later life. The role of plant-derived alpha-linolenic acid in brain health requires further investigation.
Source: JAHA:Journal of the American Heart Association - October 10, 2013 Category: Cardiology Authors: Virtanen, J. K., Siscovick, D. S., Lemaitre, R. N., Longstreth, W. T., Spiegelman, D., Rimm, E. B., King, I. B., Mozaffarian, D. Tags: Stroke Source Type: research

Clopidogrel Use Is Associated With an Increased Prevalence of Cerebral Microbleeds in a Stroke-Free Population: The Rotterdam Study Stroke
Conclusions In stroke-free individuals, clopidogrel use was associated with a higher prevalence and higher number of CMBs. Whether this association is causal requires confirmation in prospective studies, especially given the small number of participants taking clopidogrel and the possibility of residual confounding in this study.
Source: JAHA:Journal of the American Heart Association - September 26, 2013 Category: Cardiology Authors: Darweesh, S. K. L., Leening, M. J. G., Akoudad, S., Loth, D. W., Hofman, A., Arfan Ikram, M., Vernooij, M. W., Stricker, B. H. Tags: Stroke Source Type: research

Leukoaraiosis and Increased Cerebral Susceptibility to Ischemia: Lack of Confounding by Carotid Disease Stroke
Conclusions The association with more severe ischemic events (stroke versus TIA) and infarction on imaging is consistent with leukoaraiosis being a marker of increased cerebral susceptibility to ischemia. In contrast, the presence, severity of, and risk factors for atheromatous disease showed no association with leukoaraiosis, suggesting that these are two unrelated disease processes.
Source: JAHA:Journal of the American Heart Association - August 20, 2013 Category: Cardiology Authors: Schulz, U. G., Gruter, B. E., Briley, D., Rothwell, P. M. Tags: Stroke Source Type: research

Magnetic Resonance Imaging Profile of Blood-Brain Barrier Injury in Patients With Acute Intracerebral Hemorrhage Stroke
Conclusions BBB leakage in the brain tissue immediately bordering the hematoma can be measured and quantified by DCE MRI in human ICH. BBB leakage at 1 week is greater in larger hematomas as well as in hematomas in lobar locations and is associated with larger edema volumes.
Source: JAHA:Journal of the American Heart Association - May 24, 2013 Category: Cardiology Authors: Aksoy, D., Bammer, R., Mlynash, M., Venkatasubramanian, C., Eyngorn, I., Snider, R. W., Gupta, S. N., Narayana, R., Fischbein, N., Wijman, C. A. C. Tags: Stroke Source Type: research

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