• Filter By:
• Specialty
• Source
• Condition
• Cancer
• Infectious Disease
• Drug
• Training
• Management
• Procedure
• Therapy
• Vaccine
• Nutrition
• Country

Neuropsychological Status and Structural Brain Imaging in Adolescents With Single Ventricle Who Underwent the Fontan Procedure Congenital Heart Disease
Conclusions The neuropsychological deficits and high frequencies of structural brain abnormalities in adolescents who underwent the Fontan procedure highlight the need for research on interventions to improve the long-term outcomes in this high-risk group.
Source: JAHA:Journal of the American Heart Association - December 14, 2015 Category: Cardiology Authors: Bellinger, D. C., Watson, C. G., Rivkin, M. J., Robertson, R. L., Roberts, A. E., Stopp, C., Dunbar-Masterson, C., Bernson, D., DeMaso, D. R., Wypij, D., Newburger, J. W. Tags: Congenital Heart Disease Source Type: research

Comparison of Approaches to Revascularization in Patients With Multivessel Coronary Artery Disease Presenting With ST-Segment Elevation Myocardial Infarction: Meta-analyses of Randomized Control Trials Interventional Cardiology
Conclusion Results suggest that CR and SR compared with CL reduce major adverse cardiovascular event and revascularization rates primarily by lowering repeated percutaneous coronary intervention rates. We did not observe any increase in the rate of adverse events while using a CR or SR strategy compared with a CL approach. Current guidelines discouraging CR need to be reevaluated, and clinical judgment should prevail in treating multivessel coronary artery disease patients with ST-segment elevation myocardial infarction as data from larger RCTs accumulate.
Source: JAHA:Journal of the American Heart Association - December 14, 2015 Category: Cardiology Authors: Bajaj, N. S., Kalra, R., Aggarwal, H., Ather, S., Gaba, S., Arora, G., McGiffin, D. C., Ahmed, M., Aslibekyan, S., Arora, P. Tags: Interventional Cardiology Source Type: research

Incidence, Time Trends, and Predictors of Intracranial Hemorrhage During Long-Term Follow-up After Acute Myocardial Infarction Coronary Heart Disease
Conclusion The 1-year incidence of ICH after AMI remained stable, at 0.35%, over the study period. Advanced age, decreased renal function, and previous ischemic or hemorrhagic stroke are predictive of increased ICH risk.
Source: JAHA:Journal of the American Heart Association - December 11, 2015 Category: Cardiology Authors: Graipe, A., Binsell-Gerdin, E., Soderstrom, L., Mooe, T. Tags: Coronary Heart Disease Source Type: research

Incremental Value of the CRUSADE, ACUITY, and HAS-BLED Risk Scores for the Prediction of Hemorrhagic Events After Coronary Stent Implantation in Patients Undergoing Long or Short Duration of Dual Antiplatelet Therapy Coronary Heart Disease
Conclusions Our analysis suggests that the CRUSADE score predicts major bleeding similarly to ACUITY and better than HAS BLED in an all-comer population with percutaneous coronary intervention and potentially identifies patients at higher risk of hemorrhagic complications when treated with a long-term dual antiplatelet therapy regimen. Clinical Trial Registration URL: http://clinicaltrials.gov. Unique identifier: NCT00611286.
Source: JAHA:Journal of the American Heart Association - December 7, 2015 Category: Cardiology Authors: Costa, F., Tijssen, J. G., Ariotti, S., Giatti, S., Moscarella, E., Guastaroba, P., De Palma, R., Ando, G., Oreto, G., Zijlstra, F., Valgimigli, M. Tags: Coronary Heart Disease Source Type: research

Blood Pressure Control and Risk of Stroke or Systemic Embolism in Patients With Atrial Fibrillation: Results From the Apixaban for Reduction in Stroke and Other Thromboembolic Events in Atrial Fibrillation (ARISTOTLE) Trial Stroke
Conclusions High BP measurement at any point during the trial was independently associated with a substantially higher risk of stroke or systemic embolism. These results strongly support efforts to treat elevated BP as an important strategy to optimally lower risk of stroke in patients with AF. Clinical Trial Registration URL: https://ClinicalTrials.gov/. Unique identifier: NCT00412984.
Source: JAHA:Journal of the American Heart Association - December 1, 2015 Category: Cardiology Authors: Rao, M. P., Halvorsen, S., Wojdyla, D., Thomas, L., Alexander, J. H., Hylek, E. M., Hanna, M., Bahit, M. C., Lopes, R. D., De Caterina, R., Erol, C., Goto, S., Lanas, F., Lewis, B. S., Husted, S., Gersh, B. J., Wallentin, L., Granger, C. B., the Apixaban Tags: Stroke Source Type: research

Effect Modification of Long-Term Air Pollution Exposures and the Risk of Incident Cardiovascular Disease in US Women Epidemiology
Conclusions In this nationwide cohort, women with diabetes were identified as the subpopulation most sensitive to the adverse cardiovascular health effects of PM.
Source: JAHA:Journal of the American Heart Association - November 25, 2015 Category: Cardiology Authors: Hart, J. E., Puett, R. C., Rexrode, K. M., Albert, C. M., Laden, F. Tags: Epidemiology Source Type: research

N-glycome Profile Levels Relate to Silent Brain Infarcts in a Cohort of Hypertensives Imaging
Conclusions N-glycome levels might be potentially useful as biomarkers for the presence of silent cerebrovascular disease.
Source: JAHA:Journal of the American Heart Association - November 23, 2015 Category: Cardiology Authors: Vilar-Bergua, A., Riba-Llena, I., Vanhooren, V., Dewaele, S., Libert, C., Penalba, A., Montaner, J., Delgado, P. Tags: Imaging Source Type: research

Dysbiosis of Gut Microbiota With Reduced Trimethylamine-N-Oxide Level in Patients With Large-Artery Atherosclerotic Stroke or Transient Ischemic Attack Stroke
Conclusions Participants with asymptomatic atherosclerosis did not exhibit an obvious change in gut microbiota and blood TMAO levels; however, stroke and transient ischemic attack patients showed significant dysbiosis of the gut microbiota, and their blood TMAO levels were decreased.
Source: JAHA:Journal of the American Heart Association - November 23, 2015 Category: Cardiology Authors: Yin, J., Liao, S.-X., He, Y., Wang, S., Xia, G.-H., Liu, F.-T., Zhu, J.-J., You, C., Chen, Q., Zhou, L., Pan, S.-Y., Zhou, H.-W. Tags: Stroke Source Type: research

"Life's Simple 7" and Long-Term Mortality After Stroke Stroke
Conclusions Achieving a greater number of ideal cardiovascular health metrics is associated with lower long-term risk of dying after stroke. Specifically targeting "Life's Simple 7" goals might have a profound impact, extending survival after stroke.
Source: JAHA:Journal of the American Heart Association - November 20, 2015 Category: Cardiology Authors: Lin, M. P., Ovbiagele, B., Markovic, D., Towfighi, A. Tags: Stroke Source Type: research

Long-Term Risk of Stroke in Patients With Type 1 and Type 2 Diabetes Following Coronary Artery Bypass Grafting Cardiovascular Surgery
Conclusions The long-term risk for stroke after coronary artery bypass grafting was increased in patients with type 1 and type 2 diabetes, compared to patients with no diabetes.
Source: JAHA:Journal of the American Heart Association - November 9, 2015 Category: Cardiology Authors: Nystrom, T., Holzmann, M. J., Sartipy, U. Tags: Cardiovascular Surgery Source Type: research

Thiosulfate Mediates Cytoprotective Effects of Hydrogen Sulfide Against Neuronal Ischemia Stroke
Conclusions The protective effects of H2S are mediated by thiosulfate that is transported across cell membrane by NaS-2 and exerts antiapoptotic effects via persulfidation of caspase-3. Given the established safety track record, thiosulfate may be therapeutic against ischemic brain injury.
Source: JAHA:Journal of the American Heart Association - November 6, 2015 Category: Cardiology Authors: Marutani, E., Yamada, M., Ida, T., Tokuda, K., Ikeda, K., Kai, S., Shirozu, K., Hayashida, K., Kosugi, S., Hanaoka, K., Kaneki, M., Akaike, T., Ichinose, F. Tags: Stroke Source Type: research

Patterns of Anticoagulation Use and Cardioembolic Risk After Catheter Ablation for Atrial Fibrillation Arrhythmia and Electrophysiology
Conclusion The overall risk of stroke in postablation patients is low; however, OAC discontinuation after ablation is common and is associated with increased risk of cardioembolism for all patients within the first 3 months and for high-risk patients in the long term. Continuing OAC for at least 3 months in all patients and indefinitely in high-risk patients appears to be the safest strategy.
Source: JAHA:Journal of the American Heart Association - November 5, 2015 Category: Cardiology Authors: Noseworthy, P. A., Yao, X., Deshmukh, A. J., Van Houten, H., Sangaralingham, L. R., Siontis, K. C., Piccini, J. P., Asirvatham, S. J., Friedman, P. A., Packer, D. L., Gersh, B. J., Shah, N. D. Tags: Arrhythmia and Electrophysiology Source Type: research

Acquisition, Analysis, and Sharing of Data in 2015 and Beyond: A Survey of the Landscape: A Conference Report From the American Heart Association Data Summit 2015 AHA Conference Proceedings
Conclusion There was a consensus across stakeholder domains that Big Data holds great promise for revolutionizing the way cardiovascular and stroke research is conducted and clinical care is delivered; however, there is a clear need for the creation of a vision of how to use it to achieve the desired goals. Potential roles for the AHA center around facilitating a discussion of standards, providing education, and helping establish a cardiovascular digital ecosystem. This ecosystem should be interoperable and needs to interface with the rapidly growing digital object environment of the modern-day healthcare system.
Source: JAHA:Journal of the American Heart Association - November 5, 2015 Category: Cardiology Authors: Antman, E. M., Benjamin, E. J., Harrington, R. A., Houser, S. R., Peterson, E. D., Bauman, M. A., Brown, N., Bufalino, V., Califf, R. M., Creager, M. A., Daugherty, A., Demets, D. L., Dennis, B. P., Ebadollahi, S., Jessup, M., Lauer, M. S., Lo, B., MacRae Tags: AHA Conference Proceedings Source Type: research

Individual Proton Pump Inhibitors and Outcomes in Patients With Coronary Artery Disease on Dual Antiplatelet Therapy: A Systematic Review Coronary Heart Disease
Conclusions Several frequently used PPIs previously thought to be safe for concomitant use with clopidogrel were associated with greater risk of adverse cardiovascular events. Although the data are observational, they highlight the need for randomized controlled trials to evaluate the safety of concomitant PPI and clopidogrel use in patients with coronary artery disease.
Source: JAHA:Journal of the American Heart Association - October 29, 2015 Category: Cardiology Authors: Sherwood, M. W., Melloni, C., Jones, W. S., Washam, J. B., Hasselblad, V., Dolor, R. J. Tags: Coronary Heart Disease Source Type: research

Reducing the Blood Pressure-Related Burden of Cardiovascular Disease: Impact of Achievable Improvements in Blood Pressure Prevention and Control Epidemiology
Conclusions Modest population-wide shifts in systolic blood pressure could have a substantial impact on cardiovascular disease incidence and should be developed in parallel with interventions targeting populations with blood pressure above goal.
Source: JAHA:Journal of the American Heart Association - October 27, 2015 Category: Cardiology Authors: Hardy, S. T., Loehr, L. R., Butler, K. R., Chakladar, S., Chang, P. P., Folsom, A. R., Heiss, G., MacLehose, R. F., Matsushita, K., Avery, C. L. Tags: Epidemiology Source Type: research

Pages: 1  2  3  4  5  6  7  8  9  10  11  12  13  14  15  16  17  18  19  20