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Source: JAHA:Journal of the American Heart Association
Condition: Ischemic Stroke

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Total 169 results found since Jan 2013.

Impact of Atrial Fibrillation on Stroke-Related Healthcare Costs Stroke
Conclusion Stroke-related care for IS, HS, and TIA is costly, especially among individuals with AF. Reducing the risk of AF-related stroke is important from both clinical and economic standpoints.
Source: JAHA:Journal of the American Heart Association - November 25, 2013 Category: Cardiology Authors: Sussman, M., Menzin, J., Lin, I., Kwong, W. J., Munsell, M., Friedman, M., Selim, M. Tags: Stroke Source Type: research

Impact of Atrial Fibrillation on Stroke-Related Healthcare Costs Hypertension
Conclusion Stroke-related care for IS, HS, and TIA is costly, especially among individuals with AF. Reducing the risk of AF-related stroke is important from both clinical and economic standpoints.
Source: JAHA:Journal of the American Heart Association - November 25, 2013 Category: Cardiology Authors: Sussman, M., Menzin, J., Lin, I., Kwong, W. J., Munsell, M., Friedman, M., Selim, M. Tags: Hypertension Source Type: research

Early Adoption of Dabigatran and Its Dosing in US Patients With Atrial Fibrillation: Results From the Outcomes Registry for Better Informed Treatment of Atrial Fibrillation Health Services and Outcomes Research
Conclusions Patients receiving dabigatran were younger and at a lower risk of stroke and bleeding. Patients appeared to drive switching from warfarin, whereas clinical characteristics influenced de novo start of dabigatran. These data suggest cautious early uptake of dabigatran, and more careful attention to dosing adjustments is warranted. Clinical Trial Registration URL: Clinicaltrials.gov. Unique identifier: NCT01165710.
Source: JAHA:Journal of the American Heart Association - November 25, 2013 Category: Cardiology Authors: Steinberg, B. A., Holmes, D. N., Piccini, J. P., Ansell, J., Chang, P., Fonarow, G. C., Gersh, B., Mahaffey, K. W., Kowey, P. R., Ezekowitz, M. D., Singer, D. E., Thomas, L., Peterson, E. D., Hylek, E. M., The Outcomes Registry for Better Informed Treatme Tags: Health Services and Outcomes Research Source Type: research

Incidence and Risk Factors of Cerebrovascular Events Following Cardiac Catheterization Stroke
Conclusion In a single-center, retrospective assessment over nearly 20 years, cardiac catheterization-related CVEs were very rare and nearly exclusively ischemic. The independent predictors for these events were found to be the performance of an intervention and those associated with increased atherosclerotic burden, specifically older age, triple vessel disease, and prior stroke. The presence of intracoronary thrombus appears also to raise the risk of procedure-related CVE.
Source: JAHA:Journal of the American Heart Association - November 14, 2013 Category: Cardiology Authors: Korn-Lubetzki, I., Farkash, R., Pachino, R. M., Almagor, Y., Tzivoni, D., Meerkin, D. Tags: Stroke Source Type: research

Comparison of Performance Achievement Award Recognition With Primary Stroke Center Certification for Acute Ischemic Stroke Care Stroke
Conclusions While both PSC certification and GWTG-Stroke PAA recognition identified hospitals providing higher conformity with care measures for patients hospitalized with acute ischemic stroke, PAA recognition was a more robust identifier of hospitals with better performance.
Source: JAHA:Journal of the American Heart Association - October 14, 2013 Category: Cardiology Authors: Fonarow, G. C., Liang, L., Smith, E. E., Reeves, M. J., Saver, J. L., Xian, Y., Hernandez, A. F., Peterson, E. D., Schwamm, L. H., GWTG-Stroke Steering Committee & Investigators Tags: Stroke Source Type: research

Circulating Omega-3 Polyunsaturated Fatty Acids and Subclinical Brain Abnormalities on MRI in Older Adults: The Cardiovascular Health Study Stroke
Conclusions Among older adults, higher phospholipid long-chain omega-3 PUFA content was associated with lower prevalence of subclinical infarcts and better white matter grade on MRI. Our results support the beneficial effects of fish consumption, the major source of long-chain omega-3 PUFAs, on brain health in later life. The role of plant-derived alpha-linolenic acid in brain health requires further investigation.
Source: JAHA:Journal of the American Heart Association - October 10, 2013 Category: Cardiology Authors: Virtanen, J. K., Siscovick, D. S., Lemaitre, R. N., Longstreth, W. T., Spiegelman, D., Rimm, E. B., King, I. B., Mozaffarian, D. Tags: Stroke Source Type: research

Hostility, Health Behaviors, and Risk of Recurrent Events in Patients With Stable Coronary Heart Disease: Findings From the Heart and Soul Study Epidemiology
Conclusions Hostility was a significant predictor of secondary events in this sample of outpatients with baseline stable CHD. Much of this association was moderated by poor health behaviors, specifically physical inactivity and smoking.
Source: JAHA:Journal of the American Heart Association - September 30, 2013 Category: Cardiology Authors: Wong, J. M., Na, B., Regan, M. C., Whooley, M. A. Tags: Epidemiology Source Type: research

Association of Geographical Factors With Administration of Tissue Plasminogen Activator for Acute Ischemic Stroke Stroke
Conclusion The association between ambulance use and tPA administration suggests the importance of calling an ambulance for suspected stroke. Promoting ambulance use for acute ischemic stroke patients may increase tPA use.
Source: JAHA:Journal of the American Heart Association - September 17, 2013 Category: Cardiology Authors: Kunisawa, S., Morishima, T., Ukawa, N., Ikai, H., Otsubo, T., Ishikawa, K. B., Yokota, C., Minematsu, K., Fushimi, K., Imanaka, Y. Tags: Stroke Source Type: research

Trials to Improve Blood Pressure Through Adherence to Antihypertensives in Stroke/TIA: Systematic Review and Meta-Analysis Stroke
Conclusions Multifactorial interventions including a component to improve medication adherence can lower blood pressure after stroke/TIA. However, it is not possible to say whether or not this is achieved through better medication adherence. Trials are needed of well-characterized interventions to improve medication adherence and clinical outcomes with measurement along the hypothesized causal pathway.
Source: JAHA:Journal of the American Heart Association - August 20, 2013 Category: Cardiology Authors: De Simoni, A., Hardeman, W., Mant, J., Farmer, A. J., Kinmonth, A. L. Tags: Stroke Source Type: research

Leukoaraiosis and Increased Cerebral Susceptibility to Ischemia: Lack of Confounding by Carotid Disease Stroke
Conclusions The association with more severe ischemic events (stroke versus TIA) and infarction on imaging is consistent with leukoaraiosis being a marker of increased cerebral susceptibility to ischemia. In contrast, the presence, severity of, and risk factors for atheromatous disease showed no association with leukoaraiosis, suggesting that these are two unrelated disease processes.
Source: JAHA:Journal of the American Heart Association - August 20, 2013 Category: Cardiology Authors: Schulz, U. G., Gruter, B. E., Briley, D., Rothwell, P. M. Tags: Stroke Source Type: research

Simple Integer Risk Score to Determine Prognosis of Patients With Hypertension and Chronic Stable Coronary Artery Disease Coronary Heart Disease
Conclusion Readily available clinical variables can rapidly stratify patients with hypertension and chronic stable CAD into useful risk categories.
Source: JAHA:Journal of the American Heart Association - August 15, 2013 Category: Cardiology Authors: Bavry, A. A., Kumbhani, D. J., Gong, Y., Handberg, E. M., Cooper-DeHoff, R. M., Pepine, C. J. Tags: Coronary Heart Disease Source Type: research

Risk of Ischemic Cerebrovascular and Coronary Events in Adult Users of Anticonvulsant Medications in Routine Care Settings Stroke
Conclusions In this exploratory analysis, there was no evidence of a consistent and statistically significant effect of initiating anticonvulsants that highly induce cytochrome P450 activity on ischemic coronary or cerebrovascular outcomes compared with other agents, given routine care utilization patterns.
Source: JAHA:Journal of the American Heart Association - July 30, 2013 Category: Cardiology Authors: Patorno, E., Glynn, R. J., Hernandez-Diaz, S., Avorn, J., Wahl, P. M., Bohn, R. L., Mines, D., Liu, J., Schneeweiss, S. Tags: Stroke Source Type: research

Paradoxical Association of Smoking With In-Hospital Mortality Among Patients Admitted With Acute Ischemic Stroke Stroke
Conclusions Similar to myocardial ischemia, smoking was independently associated with lower inpatient mortality in acute ischemic stroke. This effect may be due to tobacco-induced changes in cerebrovascular vasoreactivity, or may be due in part to residual confounding. Larger, multicenter studies are needed to confirm the finding and the effect on 30-day and 1-year mortality.
Source: JAHA:Journal of the American Heart Association - June 19, 2013 Category: Cardiology Authors: Ali, S. F., Smith, E. E., Bhatt, D. L., Fonarow, G. C., Schwamm, L. H. Tags: Stroke Source Type: research

A New Risk Scheme to Predict Ischemic Stroke and Other Thromboembolism in Atrial Fibrillation: The ATRIA Study Stroke Risk Score Arrhythmia and Electrophysiology
Conclusions The ATRIA stroke risk score performed better than existing risk scores, was validated successfully, and showed improvement in predicting severe events, which is of greatest concern. The ATRIA score should improve the antithrombotic decision for patients with AF and should provide a secure foundation for the addition of biomarkers in future prognostic models.
Source: JAHA:Journal of the American Heart Association - June 19, 2013 Category: Cardiology Authors: Singer, D. E., Chang, Y., Borowsky, L. H., Fang, M. C., Pomernacki, N. K., Udaltsova, N., Reynolds, K., Go, A. S. Tags: Arrhythmia and Electrophysiology Source Type: research

Joint Commission Primary Stroke Centers Utilize More rt-PA in the Nationwide Inpatient Sample Stroke
Conclusions Subjects evaluated at PSCs were more likely to receive rt-PA than those evaluated at non-PSCs. This association was significant after adjustment for patient and hospital-level variables. Systems of care are necessary to ensure stroke patients have rapid access to PSCs throughout the United States.
Source: JAHA:Journal of the American Heart Association - March 26, 2013 Category: Cardiology Authors: Mullen, M. T., Kasner, S. E., Kallan, M. J., Kleindorfer, D. O., Albright, K. C., Carr, B. G. Tags: Stroke Source Type: research