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Abstract P443: Multiple Chronic Conditions in Older Adults: Implications for Clinical Trials & Guidelines in Hypertension Session Title: Hypertension and Aging and Cerebrovascular Disease and Stroke
Conclusions: HTN impacts ~82% of older adults with a higher burden of MCC, and ~75% (27,324/36,533) of Medicare beneficiaries with HTN have a large burden of MCCs. Behavioral health diagnosis, associated with adverse outcomes and costs, are common with MCCs. Clinical care, outcomes and costs for older adults with HTN and MCCs could improve with more representative inclusion in clinical trials and translation through integrated clinical guidelines developed by multi-specialty/disciplinary teams.
Source: Hypertension - September 14, 2017 Category: Cardiology Authors: Brent M Egan, Susan E Sutherland, Valinda Rutledge, Robert A Davis, Peter L Tilkemeier, Angelo Sinopoli Tags: Poster Abstract Presentations Source Type: research

Blood Pressure Trajectories and the Risk of Intracerebral Hemorrhage and Cerebral InfarctionNovelty and Significance Epidemiology/Population
The association between long-term blood pressure (BP) patterns in community-dwelling adults and risk of intracerebral hemorrhage and cerebral infarction is not well characterized. This prospective study included 79 385 participants, free of stroke, myocardial infarction, and cancer in or before 2010 (baseline). Systolic BP trajectories were identified using latent mixture modeling with data from 2006, 2008, and 2010. Incident cases of intracerebral hemorrhage and cerebral infarction occurred during 2010 to 2014, confirmed by review of medical records, by 3 physicians. We identified 5 distinct systolic BP trajectories durin...
Source: Hypertension - August 9, 2017 Category: Cardiology Authors: Weijuan Li, Cheng Jin, Anand Vaidya, Yuntao Wu, Kathryn Rexrode, Xiaoming Zheng, Mahmut E. Gurol, Chaoran Ma, Shouling Wu, Xiang Gao Tags: Cardiovascular Disease, Epidemiology, High Blood Pressure Original Articles Source Type: research

Earlier Age of Onset of Chronic Hypertension and Type 2 Diabetes Mellitus After a Hypertensive Disorder of Pregnancy or Gestational Diabetes Mellitus Epidemiology/Population
A prospective cohort study was conducted to assess the impact of a history of hypertensive disorder of pregnancy (HDP) or gestational diabetes mellitus (GDM) on the risk and age of onset of hypertension, type 2 diabetes mellitus (T2D), and cardiovascular disease (CVD) later in life, independent of hypertension and T2D. Between 1993 and 1997, 22 265 ever-pregnant women were included from the European Prospective Investigation into Cancer and Nutrition-NL study, aged 20 to 70 years at baseline. Details on complications of pregnancy and known hypertension were obtained by questionnaire. Blood pressure was measured at enrollme...
Source: Hypertension - November 11, 2015 Category: Cardiology Authors: Heida, K. Y., Franx, A., van Rijn, B. B., Eijkemans, M. J. C., Boer, J. M. A., Verschuren, M. W. M., Oudijk, M. A., Bots, M. L., van der Schouw, Y. T. Tags: Cardiovascular Disease, Diabetes, Type 2, Epidemiology, Primary Prevention, Cerebrovascular Disease/Stroke Epidemiology/Population Source Type: research

Use of Nonsteroidal Anti-Inflammatory Drugs and Risk of Chronic Kidney Disease in Subjects With Hypertension: Nationwide Longitudinal Cohort Study Kidney
Limited studies have examined the effects of nonsteroidal anti-inflammatory drug (NSAID) use on the risk of chronic kidney disease (CKD), especially in subjects with hypertension. Using National Health Insurance claims data in Taiwan, we conducted a propensity score–matched cohort study to investigate the relationship between NSAID use and CKD in subjects with hypertension. A total of 31976 subjects were included in this study: subjects not taking any NSAIDs in 2007 (n=10782); subjects taking NSAIDs for 1 to 89 days in 2007 (n=10605); and subjects taking NSAIDs for ≥90 days in 2007 (n=10589). We performed multivar...
Source: Hypertension - August 12, 2015 Category: Cardiology Authors: Hsu, C.-C., Wang, H., Hsu, Y.-H., Chuang, S.-Y., Huang, Y.-W., Chang, Y.-K., Liu, J.-S., Hsiung, C. A., Tsai, H.-J. Tags: Clinical Studies Kidney Source Type: research