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Total 39 results found since Jan 2013.

The modifying effect of the MTHFR genotype on the association between folic acid supplementation and pulse wave velocity: Findings from the CSPPT
ConclusionIn a subgroup of Chinese hypertensive patients who had received 5 ‐year antihypertensive therapy, increases in folate status were associated with higher reductions in PWV, and individuals with the CC genotype showed greatest PWV response to folic acid supplementation.
Source: Cardiovascular Therapeutics - January 28, 2019 Category: Cardiology Authors: Xin Yang, Minghua Zhang, Rensheng Song, Changfu Liu, Yong Huo, Geng Qian Tags: ORIGINAL RESEARCH ARTICLE Source Type: research

Predicting long ‐term ischemic events using routine clinical parameters in patients with coronary artery disease: The OPT‐CAD risk score
ConclusionsAmong CAD patients, a risk score based on 10 baseline clinical variables performed better than the GRACE risk score in predicting long ‐term ischemic events. However, further research is needed to assess the value of the OPT‐CAD score in guiding the management of antiplatelet therapy for patients with CAD.
Source: Cardiovascular Therapeutics - September 12, 2018 Category: Cardiology Authors: Yaling Han, Jiyan Chen, Miaohan Qiu, Yi Li, Jing Li, Yingqing Feng, Jian Qiu, Liang Meng, Yihong Sun, Guizhou Tao, Zhaohui Wu, Chunyu Yang, Jincheng Guo, Kui Pu, Shaoliang Chen, Xiaozeng Wang Tags: ORIGINAL RESEARCH ARTICLE Source Type: research

Safety and efficacy of nonvitamin K antagonist oral anticoagulants during catheter ablation of atrial fibrillation: A systematic review and meta ‐analysis
ConclusionsUse of NOACs compared to VKAs significantly reduced the risk of bleeding in patients with AF ablation. Similarly, the risk of bleeding was lower with uninterrupted NOACs than with uninterrupted VKAs, and with interrupted NOACs than with interrupted VKAs. The rate of thromboembolic complications was extremely low in both study groups without any differences.
Source: Cardiovascular Therapeutics - September 12, 2018 Category: Cardiology Authors: Zhen Ge, Michela Faggioni, Usman Baber, Samantha Sartori, Sabato Sorrentino, Serdar Farhan, Jaya Chandrasekhar, Birgit Vogel, Abdul Qadeer, Jonathan Halperin, Vivek Reddy, Srinivas Dukkipati, George Dangas, Roxana Mehran Tags: ORIGINAL RESEARCH ARTICLE Source Type: research

Warfarin prescription in patients with nonvalvular atrial fibrillation and one non –gender‐related risk factor (CHA2DS2VASc 1 or 2): A treatment dilemma
ConclusionWe found an elevated risk of major bleeding and intracranial hemorrhage in NVAF individuals treated with warfarin with 1 NGR risk factor for stroke. These data call for caution when treating with warfarin these individuals.
Source: Cardiovascular Therapeutics - November 11, 2017 Category: Cardiology Authors: Gentian Denas, Giacomo Zoppellaro, Seena Padayattil Jose, Emilia Antonucci, Francesco Marongiu, Daniela Poli, Sophie Testa, Armando Tripodi, Gualtiero Palareti, Vittorio Pengo Tags: ORIGINAL RESEARCH ARTICLE Source Type: research

Warfarin prescription in patients with non ‐valvular atrial fibrillation and one non‐gender related risk factor (CHA2DS2VASc 1 or 2): a treatment dilemma
ConclusionWe found an elevated risk of major bleeding and intracranial haemorrhage in AF individuals treated with warfarin with 1 NGR risk factor for stroke. These data call for caution when treating with warfarin these individuals.This article is protected by copyright. All rights reserved.
Source: Cardiovascular Therapeutics - October 1, 2017 Category: Cardiology Authors: Gentian Denas, Giacomo Zoppellaro, Seena Padayattil Jose, Emilia Antonucci, Francesco Marongiu, Daniela Poli, Sophie Testa, Armando Tripodi, Gualtiero Palareti, Vittorio Pengo Tags: Original Research Article Source Type: research

The relationship between knowledge, health literacy, and adherence among patients taking oral anticoagulants for stroke thromboprophylaxis in atrial fibrillation
ConclusionSignificant correlations between health literacy, OAC knowledge, and adherence were observed, and these relationships should to be considered by health professionals responsible for monitoring patients who are prescribed anticoagulants. We also observed serious gaps in OAC knowledge. Interventions designed to optimize the outcomes of anticoagulant treatment need to address these factors.
Source: Cardiovascular Therapeutics - September 25, 2017 Category: Cardiology Authors: Chanelle A. Rolls, Kehinde O. Obamiro, Leanne Chalmers, Luke R. E. Bereznicki Tags: ORIGINAL RESEARCH ARTICLE Source Type: research

The relationship between knowledge, health literacy and adherence among patients taking oral anticoagulants for stroke thromboprophylaxis in atrial fibrillation
ConclusionSignificant correlations between health literacy, OAC knowledge and adherence were observed, and these relationships should to be considered by health professionals responsible for monitoring patients who are prescribed anticoagulants. We also observed serious gaps in OAC knowledge. Interventions designed to optimize the outcomes of anticoagulant treatment need to address these factors.This article is protected by copyright. All rights reserved.
Source: Cardiovascular Therapeutics - August 1, 2017 Category: Cardiology Authors: Chanelle A Rolls, Kehinde O Obamiro, Leanne Chalmers, Luke R E Bereznicki Tags: Original Research Article Source Type: research

Gender ‐related differences in antiplatelet treatment patterns and outcome: Insights from the GReekAntiPlatElet Registry
ConclusionsIn a contemporary “real‐life” cohort of patients with ACS treated with PCI and focusing on antiplatelet treatment 1‐year ischemic outcome does not differ by gender, while women do present more frequently not actionable bleeding events.
Source: Cardiovascular Therapeutics - July 14, 2017 Category: Cardiology Authors: Ioanna Xanthopoulou, Periklis Davlouros, Spyridon Deftereos, Michalis Hamilos, George Sitafidis, Ioannis Kanakakis, Manolis Vavouranakis, John Goudevenos, John Lekakis, Dimitrios Alexopoulos Tags: ORIGINAL RESEARCH ARTICLE Source Type: research

Effect of postprocedural full ‐dose infusion of bivalirudin on acute stent thrombosis in patients with ST‐elevation myocardial infarction undergoing primary percutaneous coronary intervention: Outcomes in a large real‐world population
ConclusionPost‐PCI full‐dose bivalirudin infusion is safe and has a trend to protect against acute ST in STEMI patients undergoing primary PCI in real‐world settings.
Source: Cardiovascular Therapeutics - May 12, 2017 Category: Cardiology Authors: Heyang Wang, Zhenyang Liang, Yi Li, Bin Li, Junming Liu, Xueyi Hong, Xin Lu, Jiansheng Wu, Wei Zhao, Qiang Liu, Jian An, Linfeng Li, Fanli Pu, Qiang Ming, Yaling Han Tags: ORIGINAL RESEARCH ARTICLE Source Type: research

Percutaneous coronary intervention vs coronary artery bypass grafting for left main coronary artery disease? A systematic review and meta ‐analysis of randomized controlled trials
ConclusionPercutaneous coronary intervention could be as safe and effective as CABG in a select group of left main coronary artery disease patients.
Source: Cardiovascular Therapeutics - May 12, 2017 Category: Cardiology Authors: Sharan P. Sharma, Khagendra Dahal, Jaspreet Khatra, Alan Rosenfeld, Juyong Lee Tags: ORIGINAL RESEARCH ARTICLE Source Type: research

Gender related differences in antiplatelet treatment patterns and outcome: insights from the GreekAntiPlatElet(GRAPE) Registry
ConclusionsIn a contemporary ‘real life’ cohort of ACS patients treated with PCI and focusing on antiplatelet treatment one‐year ischemic outcome does not differ by gender, while women do present more frequently not actionable bleeding events.This article is protected by copyright. All rights reserved.
Source: Cardiovascular Therapeutics - April 1, 2017 Category: Cardiology Authors: I. Xanthopoulou, P. Davlouros, S. Deftereos, M. Hamilos, G. Sitafidis, I. Kanakakis, M. Vavouranakis, J. Goudevenos, J. Lekakis, D. Alexopoulos Tags: Original Research Article Source Type: research

Percutaneous Coronary Intervention versus Coronary Artery Bypass Grafting for left main coronary artery disease? A systematic review and meta ‐analysis of randomized controlled trials
ConclusionPCI could be as safe and effective as CABG in a select group of left main coronary artery disease patients.This article is protected by copyright. All rights reserved.
Source: Cardiovascular Therapeutics - March 30, 2017 Category: Cardiology Authors: Sharan P Sharma, Khagendra Dahal, Jaspreet Khatra, Alan Rosenfeld, Juyoung Lee Tags: Original Research Article Source Type: research

The Tasmanian Atrial Fibrillation Study: Transition to Direct Oral Anticoagulants 2011 ‐2015
ConclusionsDOACs rapidly became the most commonly prescribed class of antithrombotic medications in patients with AF soon after they became widely available. Warfarin and antiplatelet prescribing declined significantly, although a substantial proportion of patients continued to be prescribed antiplatelet therapy. Patients who were initiated on DOACs were typically younger with fewer comorbid conditions compared to those initiated on warfarin therapy.This article is protected by copyright. All rights reserved.
Source: Cardiovascular Therapeutics - January 31, 2017 Category: Cardiology Authors: Endalkachew Admassie Alamneh, Leanne Chalmers, Luke R. Bereznicki Tags: Original Research Article Source Type: research