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Use of TEG/Platelet Mapping to Dose-Adjust Platelet Inhibitors in Children Supported with the Berlin EXCOR: In Search of a Correlation
There is uncertain correlation between doses of aspirin (ASA), dipyridamole (DPM) and clopidogrel (CLP) and the absolute % inhibition as measured by Platelet Mapping, a platelet function test that accompanies Thromboelastography (TEG). This is particularly relevant for children supported with the Berlin EXCOR pediatric ventricular assist device (VAD), as the TEG/PM is currently used to adjust their antiplatelet medications but the stroke rate remains unacceptably high. We sought to determine whether there was better correlation between medication doses and the relative change from baseline in the % inhibition.
Source: The Journal of Heart and Lung Transplantation - March 25, 2017 Category: Transplant Surgery Authors: L.J. May, X. Liu, C. Sherwin, L. Yang, J. Zhender, J. Lee, S. Chen, D.N. Rosenthal, C.S. Almond Source Type: research