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Prevalence and predictors of statin utilization among patient populations at high vascular risk in Ghana
Inadequate implementation of evidence-based preventive measures for individuals at high risk of cardiovascular disease (CVD) will only worsen the current epidemic of CVDs in sub-Saharan Africa. We assessed rates and predictors of statin utilization among two high CVD risk patient populations, people with type 2 diabetes mellitus (T2DM) and those with stroke, encountered across five hospitals in Ghana.
Source: Journal of the Neurological Sciences - April 14, 2020 Category: Neurology Authors: Fred Stephen Sarfo, Bruce Ovbiagele Source Type: research

Effect of icosapent ethyl on stroke risk: Different strokes for different folks?
In the Reduction of Cardiovascular Events with Icosapent Ethyl –Intervention Trial (REDUCE-IT) [1], among patients with elevated triglycerides on statins, ischemic event risk was lower among those who received icosapent ethyl vs. placebo. However, while coronary events were reduced in both REDUCE-IT and another pure EPA trial, Japan EPA lipid intervention stu dy (JELIS) [2], ischemic stroke risk was lowered in REDUCE-IT (HR 0.64, 0.49-0.85), but not decreased in JELIS (HR 0.97, 0.85-1.10). The discrepancy between these two pure EPA trials might be due to the varied race-ethnicity composition of participants, since partic...
Source: Journal of the Neurological Sciences - April 18, 2019 Category: Neurology Authors: Meng Lee, Bruce Ovbiagele Tags: Letter to the Editor Source Type: research

Letter by Huang regarding the article, “Statin use increases the risk of depressive disorder in stroke patients: A population-based study”
I read with interest the article by Kang et al. which evaluated the risk for depressive disorder (DD) among stroke patients with statin use [1]. In a retrospective cohort study including 11,218 Chinese patients who had a first-time acute hospitalization for stroke in Taiwan, the authors followed each study subject for a 1-year period, finding that regular statin use was positively associated with the occurrence of DD following stroke. Their findings seem interesting, but I would like to raise 2 concerns.
Source: Journal of the Neurological Sciences - August 14, 2015 Category: Neurology Authors: Jian Huang Tags: Letter to the editor Source Type: research

Letter by Huang regarding article, ''Statin use increases the risk of depressive disorder in stroke patients: a population-based study''
We read with interest the article by Kang et al which evaluated the risk for depressive disorder (DD) among stroke patients with statin use [1]. In a retrospective cohort study including 11,218 Chinese patients who had a first-time acute hospitalization for stroke in Taiwan, the authors followed each study subject for a 1-year period, finding that regular statin use was positively associated with the occurrence of DD following stroke. Their findings seem interesting, but I would like to raise 2 concerns.
Source: Journal of the Neurological Sciences - August 14, 2015 Category: Neurology Authors: Jian Huang Source Type: research

Statin Use Increases the Risk of Depressive Disorder in Stroke Patients: A Population-Based Study
This study aimed to explore the risk for depressive disorder (DD) among stroke patients with statin use. Totally, 11,218 patients who had a first-time acute hospitalization for stroke were identified from Taiwan’s Longitudinal Health Insurance Database 2000. We individually followed each study subject for a 1-year period to identify those patients who were subsequently diagnosed with DD during the follow-up period. We found that the incidence rate of DD during the 1-year follow-up period was 5.52 (95% CI: 4.70~6.43) and 3.46 (95% CI: 3.08~3.88) per 100 person-years for stroke patients who were statin users and nonusers, respectively.
Source: Journal of the Neurological Sciences - November 17, 2014 Category: Neurology Authors: Jiunn-Horng Kang, Li-Ting Kao, Herng-Ching Lin, Ming-Chieh Tsai, Shiu-Dong Chung Source Type: research

Thalamic cramplike pain
Conclusions and relevance: Thalamic cramplike pain should be recognized as a type of central post-stroke pain, probably produced by lesions localized to the border between the ventral posterior and pulvinar nuclei and connected to the ipsilateral primary somatosensory cortex and primary and secondary motor cortices.
Source: Journal of the Neurological Sciences - November 7, 2013 Category: Neurology Authors: Luciano A. Sposato, Harish A. Sharma, Ali R. Khan, Robert Bartha, Vladimir Hachinski Tags: Short Communications Source Type: research

Cerebral hemorrhages in CADASIL: Report of four cases and a brief review
Conclusions: Hemorrhagic stroke can occur in CADASIL similarly to sporadic cerebral small vessel diseases; this finding expands the phenotype of the disease. A diagnosis of CADASIL should probably be considered also in patients with ICH. These data bear potential implications in terms of need of better control of risk factors, particularly hypertension, and raise relevant questions about the use of antiplatelets as prevention measures in CADASIL patients.
Source: Journal of the Neurological Sciences - May 2, 2013 Category: Neurology Authors: Valentina Rinnoci, Serena Nannucci, Raffaella Valenti, Ida Donnini, Silvia Bianchi, Francesca Pescini, Maria Teresa Dotti, Antonio Federico, Domenico Inzitari, Leonardo Pantoni Tags: Original Articles Source Type: research