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Development of a stroke risk score with MRI asymptomatic brain lesions attributes to evaluate prognostic vascular events
The use of a combination of stroke predictors, such as clinical factors and asymptomatic lesions on brain magnetic resonance imaging (MRI), may improve the accuracy of stroke risk prediction. Therefore, we attempted to develop a stroke risk score for healthy individuals.
Source: Journal of the Neurological Sciences - April 2, 2023 Category: Neurology Authors: Kenichi Iwasa, Keiichi Onoda, Masahiro Takamura, Hiroyuki Takayoshi, Shingo Mitaki, Shuhei Yamaguchi, Atsushi Nagai Source Type: research

Letter to editor: Is improved access to magnetic resonance imaging imperative for optimal ischemic stroke care?
We read the article “Is improved access to magnetic resonance imaging imperative for optimal ischemic stroke care?” [1] with great interest. The authors have presented a concise and informative summary of the use of MRI in ischemic stroke care, emphasizing its significance in diagnosis, management, and secondary pr evention. We appreciate the authors for presenting a comprehensive summary of the use of MRI in ischemic stroke care. However, we have certain points to make about the comparison of the MR scanners provided in this article.
Source: Journal of the Neurological Sciences - March 31, 2023 Category: Neurology Authors: Alex Panther Source Type: research

Computed tomography versus short sequence magnetic resonance imaging in acute ischaemic stroke
It is undisputable that the acute management of stroke requires a fast and accurate diagnostic imaging modality. We read with interest and congratulate Kumar et al. on their article discussing the superiority and benefits of the use of magnetic resonance imaging (MRI) in acute ischaemic stroke (AIS) [1]. The authors suggest that MRI can improve the diagnostic accuracy of computed tomography (CT) negative AIS and allow better selection of patients for reperfusion therapies. Moreover, MRI may help avoid hospital admissions for patients with stroke mimics, facilitate earlier discharge, reduce overall hospital costs and play a...
Source: Journal of the Neurological Sciences - March 30, 2023 Category: Neurology Authors: Ho Lun Wong, Ashraf Nasim, Amit K.J. Mandal, Robert Davies, Constantinos G. Missouris Source Type: research

Restricted access in the emergency department prevents MRI from being the workhorse for ischemic stroke care
We express our sincere gratitude to Wong et al. for their interest in our recent publication, “Is improved access to magnetic resonance imaging imperative for optimal ischemic stroke care?” [1]. We value the insights provided by the authors regarding the potential of magnetic resonance imaging (MRI) as the preferred imaging modality for acute ischemic stroke (AIS). Additionally, we appre ciate their valuable contribution on the utilization of short-sequence head MRI in addition to computed tomography (CT) for AIS evaluation at their center, which provides further evidence for the use of MRI in this context.
Source: Journal of the Neurological Sciences - March 26, 2023 Category: Neurology Authors: Mukesh Kumar, Sherry Hu, Steven Beyea, Noreen Kamal Source Type: research

Is improved access to magnetic resonance imaging imperative for optimal ischemic stroke care?
Neuroimaging, including CT and MRI, is integral to ischemic stroke (IS) treatment, management, and prevention. However, the use of MRI for IS patients is limited despite its potential to provide high-quality images that yield definitive information related to the management of IS. MRI is beneficial when the information provided by CT is insufficient for decisions related to the diagnosis, etiology, or treatment of IS. In the emergency setting, MRI can improve the diagnostic accuracy of CT-negative acute ischemic strokes (AIS) and ensure a better selection of patients for reperfusion therapies with thrombolysis and/or thrombectomy.
Source: Journal of the Neurological Sciences - February 17, 2023 Category: Neurology Authors: Mukesh Kumar, Sherry Hu, Steven Beyea, Noreen Kamal Tags: Clinical short communication Source Type: research

Significance of concurrent ipsilateral intracranial carotid artery stenosis in carotid revascularization
A 71-year-old male presenting with a transient ischemic attack was found to have an ipsilateral severe proximal right internal carotid artery (ICA) stenosis as graded per the North American Symptomatic Carotid Endarterectomy Trial (NASCET) criteria. He was subsequently treated with right internal carotid endarterectomy (CEA). The surgery was complicated by a right sided watershed infarction determined by magnetic resonance imaging (MRI) of the head. His post-surgery National Institutes of Health Stroke Scale score was 6 and the 90  days modified Rankin Scale score was 3.
Source: Journal of the Neurological Sciences - February 19, 2021 Category: Neurology Authors: Riwaj Bhagat, Allison Muha Tags: Letter to the Editor Source Type: research

Clinical characteristics and brain MRI findings in myeloproliferative neoplasms
Myeloproliferative neoplasms (MPNs) including polycythemia vera (PV) and essential thrombocythemia (ET) have an increased risk of ischemic stroke. However, little is known about brain morphological changes and the cerebral vasculature in MPNs. The aim of the present study is to clarify the prevalence rates of brain infarcts (BIs) on magnetic resonance imaging (MRI) and to assess the detailed clinical and MRI characteristics in those patients.
Source: Journal of the Neurological Sciences - June 17, 2020 Category: Neurology Authors: Koichiro Nagai, Takashi Shimoyama, Hiroki Yamaguchi, Yuki Sakamoto, Satoshi Suda, Satoshi Wakita, Yasuhiro Nishiyama, Koiti Inokuchi, Kazumi Kimura Source Type: research

A novel homoplasmic mitochondrial DNA mutation (m.13376T > C, p.I347T) of MELAS presenting characteristic medial temporal lobe atrophy
Mitochondrial myopathy, encephalopathy, lactic acidosis, and stroke-like episodes (MELAS) is a maternally inherited mitochondrial cytopathy that usually affects people under 40  years of age with variable symptoms [1]. The prevalence of MELAS syndrome in Japan was reported to be 0.2: 100,000 [2]. MELAS can be diagnosed by serum analyses under an aerobic exercise test, brain magnetic resonance imaging (MRI), muscle biopsy and mitochondrial DNA (mtDNA) analysis [3]. Approx imately 80% of MELAS cases are caused by a mutation m.3243A > G of the mitochondrial transfer RNA gene [4].
Source: Journal of the Neurological Sciences - October 24, 2019 Category: Neurology Authors: Ryo Sasaki, Yasuyuki Ohta, Noriko Hatanaka, Koh Tadokoro, Emi Nomura, Jingwei Shang, Mami Takemoto, Nozomi Hishikawa, Toru Yamashita, Yoshio Omote, Eisaku Morimoto, Sanae Teshigawara, Jun Wada, Yu-ichi Goto, Koji Abe Tags: Letter to the Editor Source Type: research

Estimating the uptake of brain imaging and 30-days stroke mortality in Nigeria: A meta-analysis of hospital-based studies
This study aims to estimate the computed tomography (CT) and Magnetic resonance imaging (MRI) uptake, stroke subtypes and 30-days case-fatality in Nigeria.
Source: Journal of the Neurological Sciences - August 23, 2018 Category: Neurology Authors: Martinsixtus Ezejimofor, Amabetare Biu, Olalekan A. Uthman Tags: Review Article Source Type: research

Clinical and radiological determinants of transient symptoms associated with infarction (TSI)
The definition of transient ischemic attack was traditionally based on clinical features only. The wide use of magnetic resonance imaging (MRI) led to the definition of a new entity - transient symptoms associated with infarction (TSI). It is unclear why patients with similar radiological infarctions may have different clinical manifestation – ranging from complete symptoms resolution to major neurological sequelae.We sought to determine which factors differentiate acute diffuse weighted imaging (DWI) lesion presentation - stroke versus TSI.
Source: Journal of the Neurological Sciences - April 23, 2018 Category: Neurology Authors: J. Molad, E. Ben-Assayag, A.D. Korczyn, E. Kliper, N.M. Bornstein, H. Hallevi, E. Auriel Source Type: research

MRI scout images can detect the acute intracerebral hemorrhage on CT
We examined whether MRI scout imaging can detect ICHs observed by computed tomography (CT).
Source: Journal of the Neurological Sciences - February 3, 2018 Category: Neurology Authors: Toshiyuki Hayashi, Junya Aoki, Kentaro Suzuki, Yuki Sakamoto, Satoshi Suda, Seiji Okubo, Masahiro Mishina, Kazumi Kimura Source Type: research

About 30% of wake-up stroke patients may be candidate for the tPA therapy using Negative-FLAIR as a “tissue clock”
Recent studies using magnetic resonance imaging (MRI) have reported that wake-up stroke (WUS) patients may be able to be treated using tissue-plasminogen activator (tPA) when showing no ischemia on fluid-attenuated inversion recovery (Negative-FLAIR). We investigated the frequency of WUS and calculated what percentage of WUS patients with Negative-FLAIR meets most of the conventional tPA criteria. We did not include a time parameter in this study.
Source: Journal of the Neurological Sciences - September 30, 2017 Category: Neurology Authors: Koichiro Nagai, Junya Aoki, Yuki Sakamoto, Kazumi Kimura Source Type: research

Association between leukoaraiosis and hemorrhagic transformation after cardioembolic stroke due to atrial fibrillation and/or rheumatic heart disease
Cardioembolic stroke due to atrial fibrillation (AF) and/or rheumatic heart disease (RHD) often involves hemorrhagic transformation (HT), and we examined whether leukoaraiosis (LA) was associated with HT in these cases. We prospectively enrolled 251 patients who were admitted to two hospitals within one month of experiencing cardioembolic stroke due to AF/RHD. LA severity was assessed using three visual rating scales. HT was identified in 99 patients (39.4%) based on baseline computed tomography (CT) and post-admission magnetic resonance imaging or second CT.
Source: Journal of the Neurological Sciences - May 2, 2017 Category: Neurology Authors: Chen-Chen Wei, Shu-Ting Zhang, Yun-Han Wang, Jun-Feng Liu, Jie Li, Ruo-Zhen Yuan, Ge Tan, Shi-Hong Zhang, Ming Liu Source Type: research

Feasibility of using magnetic resonance imaging as a screening tool for acute stroke thrombolysis
Feasibility of performing MRI first for suspected hyperacute stroke patients in real-world practice has not been fully examined. Moreover, most past studies of reducing door-to-needle time (DNT) in intravenous thrombolysis were conducted using CT. The aim of this study was to evaluate the feasibility of an MRI-first policy and examine the effects of a quality improvement (QI) process for reducing DNT using MRI.
Source: Journal of the Neurological Sciences - July 8, 2016 Category: Neurology Authors: Yuki Sakamoto, Midori Tanabe, Kyoko Masuda, Hitomi Ozaki, Seiji Okubo, Satoshi Suda, Arata Abe, Junya Aoki, Kanako Muraga, Takuya Kanamaru, Kentaro Suzuki, Takehiro Katano, Kazumi Kimura Source Type: research

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