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Computed tomography versus short sequence magnetic resonance imaging in acute ischaemic stroke
It is undisputable that the acute management of stroke requires a fast and accurate diagnostic imaging modality. We read with interest and congratulate Kumar et al. on their article discussing the superiority and benefits of the use of magnetic resonance imaging (MRI) in acute ischaemic stroke (AIS) [1]. The authors suggest that MRI can improve the diagnostic accuracy of computed tomography (CT) negative AIS and allow better selection of patients for reperfusion therapies. Moreover, MRI may help avoid hospital admissions for patients with stroke mimics, facilitate earlier discharge, reduce overall hospital costs and play a...
Source: Journal of the Neurological Sciences - March 30, 2023 Category: Neurology Authors: Ho Lun Wong, Ashraf Nasim, Amit K.J. Mandal, Robert Davies, Constantinos G. Missouris Source Type: research

Risk of readmission and mortality in patients with ischaemic stroke
Morton et al. conducted a 1-year follow-up study to evaluate the risk of readmission to hospital and all-cause mortality in patients with ischaemic stroke (IS) [1]. The cumulative incidence of all-cause readmission was 56.1%, and the adjusted hazard ratios (HRs) (95% confidence intervals [CI]) of patients with diabetes for all-cause, cardiovascular, and IS readmission were 1.13 (1.09 –1.17), 1.14 (1.07–1.21), and 1.17 (1.06–1.29). One-year mortality also increased significantly in patients with diabetes, and IS readmission and mortality were higher in women than those in men.
Source: Journal of the Neurological Sciences - September 30, 2022 Category: Neurology Authors: Tomoyuiki Kawada Source Type: research

Prevalence of stroke in acute vertigo presentations: A UK tertiary stroke centre perspective
The reported prevalence of stroke amongst patients presenting to hospital with acute vertigo and/or imbalance is c. 5%, leading to the pervasive notion amongst emergency and stroke physicians, that stroke is uncommon in this cohort.To interrogate the veracity of this notion, we systematically and retrospectively screened the electronic care records in our institution of patients referred as suspected stroke, to a hyperacute stroke service at a large tertiary referral centre.We screened 24,310 consecutive patients' electronic case records presenting to our hospital as an emergency over a 4-month period, 332 of whom were ref...
Source: Journal of the Neurological Sciences - September 12, 2022 Category: Neurology Authors: Mohammad Mahmud, Abdel Rahman Saad, Zaeem Hadi, Jordan Elliot, Mabel Prendergast, Joseph Kwan, Barry Seemungal Source Type: research

Impact of prior antiplatelet therapy on outcomes of endovascular therapy for acute ischemic stroke with large vessel occlusion: Sub-analysis of the RESCUE-Japan Registry 2
The impact of prior antiplatelet therapy (APT) on clinical outcomes of endovascular therapy (EVT) for large vessel occlusion (LVO) on clinical outcomes is uncertain. We explored the associations between prior APT and in-hospital and 90-day outcomes in a real-world setting.
Source: Journal of the Neurological Sciences - May 10, 2022 Category: Neurology Authors: Satoru Fujiwara, Nobuyuki Sakai, Hirotoshi Imamura, Nobuyuki Ohara, Kanta Tanaka, Hiroshi Yamagami, Yasushi Matsumoto, Masataka Takeuchi, Kazutaka Uchida, Shinichi Yoshimura, Takeshi Morimoto, RESCUE-Japan Registry 2 Investigators Source Type: research

Predictors of in-hospital and 90-day post-discharge stroke mortality in Lusaka, Zambia
Factors associated with stroke mortality are understudied in sub-Saharan Africa but have implications for designing interventions that improve stroke outcomes. We investigated predictors of in-hospital and 90-day post-discharge stroke mortality in Lusaka, Zambia.
Source: Journal of the Neurological Sciences - April 6, 2022 Category: Neurology Authors: Aparna Nutakki, Mashina Chomba, Lorraine Chishimba, Mataa M. Mataa, Stanley Zimba, Michelle Kvalsund, Rebecca F. Gottesman, Mona N. Bahouth, Deanna Saylor Source Type: research

One-year readmission and mortality following ischaemic stroke by diabetes status, sex, and socioeconomic disadvantage: An analysis of 27,802 strokes from 2012 to 2017
We estimated the 1-year incidence of readmission to hospital and 1-year all-cause mortality following ischaemic stroke (IS), by diabetes status, sex, and socioeconomic disadvantage.
Source: Journal of the Neurological Sciences - January 12, 2022 Category: Neurology Authors: Jedidiah I. Morton, Jenni Ilom äki, Stephen J. Wood, J. Simon Bell, Jonathan E. Shaw, Dianna J. Magliano Source Type: research

Low-dose tirofiban is associated with reduced in-hospital mortality in cardioembolic stroke patients treated with endovascular thrombectomy
Whether tirofiban is safe and effective in cardioembolic stroke patients treated with endovascular thrombectomy (EVT) remains unknown; this study evaluated the safety and efficacy of low-dose tirofiban in this patients population.
Source: Journal of the Neurological Sciences - June 14, 2021 Category: Neurology Authors: Wenbo Zhao, Jiali Xu, Sijie Li, Guiyou Liu, Longfei Wu, Chuanhui Li, Chuanjie Wu, Changhong Ren, Jian Chen, Jiangang Duan, Ruixian Wang, Haiqing Song, Qingfeng Ma, Xunming Ji Source Type: research

Risk factors and outcomes of hospitalized stroke patients in Lusaka, Zambia
Limited data exists about stroke risk factors and outcomes in sub-Saharan African countries, including Zambia. We aim to fill this gap by describing features of hospitalized stroke patients at University Teaching Hospital (UTH), the national referral hospital in Lusaka, Zambia.
Source: Journal of the Neurological Sciences - March 18, 2021 Category: Neurology Authors: Aparna Nutakki, Mashina Chomba, Lorraine Chishimba, Stanley Zimba, Rebecca F. Gottesman, Mona N. Bahouth, Deanna Saylor Source Type: research

Early-hospital readmission after generalized status epilepticus during stroke hospitalization
To assess the relationship between generalized convulsive status epilepticus (GCSE) during an index stroke hospitalization and occurrence of 30-day hospital readmission.
Source: Journal of the Neurological Sciences - November 30, 2020 Category: Neurology Authors: Alain Lekoubou, Kinfe G. Bishu, Bruce Ovbiagele Source Type: research

Impact of pulmonary embolism on in-hospital mortality of patients with ischemic stroke
Pulmonary embolism (PE) is a frequent complication in immobile stroke patients and an important cause of death in stroke patients. We aimed to investigate predictors of PE and impact of PE on survival of ischemic stroke patients.
Source: Journal of the Neurological Sciences - October 8, 2020 Category: Neurology Authors: Karsten Keller, Lukas Hobohm, Thomas M ünzel, Mareike Lankeit, Mir Abolfazl Ostad Source Type: research

The potential impact of enhanced hygienic measures during the COVID-19 outbreak on hospital-acquired infections: A pragmatic study in neurological units
This study aimed to investigate if enhanced hygienic measures, including the systematic use of personal protective equipment (PPE), determined a decrease in HAI during the recent COVID-19 outbreak in “COVID-free” neurological units.
Source: Journal of the Neurological Sciences - August 28, 2020 Category: Neurology Authors: Emanuele Cerulli Irelli, Biagio Orlando, Enrico Cocchi, Alessandra Morano, Francesco Fattapposta, Vittorio Di Piero, Danilo Toni, Maria R. Ciardi, Anna T. Giallonardo, Giovanni Fabbrini, Alfredo Berardelli, Carlo Di Bonaventura Tags: Clinical short communication Source Type: research

COVID-19 AND STROKE: Experience in a GHANAIAN healthcare system
Background:The novel coronavirus disease 19 (COVID-19) causes multi-system disease including possibly heightened stroke risk. Data from high-income countries (HIC) suggest disruptions to care delivery with reduced stroke admissions and administration of acute stroke reperfusion therapies. We are unaware of any published data on the impact of the COVID-19 pandemic on stroke admissions and outcomes in sub-Saharan Africa.Purpose: To compare rates of stroke admissions and case fatality between corresponding periods in 2020 and 2019, within a hospital system in Ghana, to assess the potential impact of the COVID-19 pandemic.
Source: Journal of the Neurological Sciences - July 14, 2020 Category: Neurology Authors: Fred S. Sarfo, Naa Oboshie Mensah, Francis Agyapong Opoku, Nathaniel Adusei-Mensah, Michael Ampofo, Bruce Ovbiagele Source Type: research

Prevalence and predictors of statin utilization among patient populations at high vascular risk in Ghana
Inadequate implementation of evidence-based preventive measures for individuals at high risk of cardiovascular disease (CVD) will only worsen the current epidemic of CVDs in sub-Saharan Africa. We assessed rates and predictors of statin utilization among two high CVD risk patient populations, people with type 2 diabetes mellitus (T2DM) and those with stroke, encountered across five hospitals in Ghana.
Source: Journal of the Neurological Sciences - April 14, 2020 Category: Neurology Authors: Fred Stephen Sarfo, Bruce Ovbiagele Source Type: research

12 versus 24  h bed rest after acute ischemic stroke thrombolysis: a preliminary experience
The practice of ≥24 h of bed rest after acute ischemic stroke thrombolysis is common among hospitals, but its value compared to shorter periods of bed rest is unknown.
Source: Journal of the Neurological Sciences - December 4, 2019 Category: Neurology Authors: Brian Silver, Tariq Hamid, Muhib Khan, Mario Di Napoli, Reza Behrouz, Gustavo Saposnik, Jo-Ann Sarafin, Susan Martin, Majaz Moonis, Nils Henninger, Richard Goddeau, Adalia Jun-O'Connell, Shawna M. Cutting, Ali Saad, Shadi Yaghi, Wiley Hall, Susanne Muehls Source Type: research

12 versus 24  h bed rest after acute ischemic stroke thrombolysis
The practice of ≥24 h of bed rest after acute ischemic stroke thrombolysis is common among hospitals, but its value compared to shorter periods of bed rest is unknown.
Source: Journal of the Neurological Sciences - December 4, 2019 Category: Neurology Authors: Brian Silver, Tariq Hamid, Muhib Khan, Mario DiNapoli, Reza Behrouz, Gustavo Saposnik, Jo-Ann Sarafin, Susan Martin, Majaz Moonis, Nils Henninger, Richard Goddeau, Adalia Jun-O'Connell, Shawna M. Cutting, Ali Saad, Shadi Yaghi, Wiley Hall, Susanne Muehlsc Source Type: research

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