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Cost of treatment failure: Medicare spending on stroke for atrial fibrillation patients not receiving anticoagulation
It is well known that atrial fibrillation (AF) patients not receiving anticoagulants are at higher risk of Ischemic Stroke (IS).
Source: Journal of the Neurological Sciences - September 19, 2023 Category: Neurology Authors: Steven D. Culler, W. Frank Peacock, April W. Simon Source Type: research

Association of non-sustained atrial tachycardia and its duration in 24-h Holter monitoring with embolic stroke of unknown source
Although supraventricular ectopic beats (SVE), including premature atrial contractions (PACs) and non-sustained atrial tachycardia (NSAT), are frequent in the general population, some study results indicate that they are pathologic. SVE may predict undiagnosed atrial fibrillation or be associated with the embolic pattern of ischemic stroke. The aim of this study was to identify the indicators most associated with embolic stroke among the parameters that suggest the burden of SVE.
Source: Journal of the Neurological Sciences - March 4, 2023 Category: Neurology Authors: Yeonggeun Choi, Yerim Kim, Sung Eun Kim, Ju-Hun Lee Source Type: research

Sustained atrial fibrillation is related to a higher severity of stroke in patients taking direct oral anticoagulants
This study aimed to investigate the differences in stroke severity at admission between patients with paroxysmal AF and sustained AF when treated with direct oral anticoagulants (DOACs).
Source: Journal of the Neurological Sciences - January 31, 2022 Category: Neurology Authors: Toshiyuki Hayashi, Satoshi Suda, Arata Abe, Yasuyuki Iguchi, Yoshiki Yagita, Takao Kanzawa, Seiji Okubo, Shigeru Fujimoto, Kazumi Kimura, on behalf of the PASTA study group Source Type: research

Prior direct oral anticoagulant dosage and outcomes in patients with acute ischemic stroke and non-valvular atrial fibrillation: A sub-analysis of PASTA registry study
This study aimed to propose a novel criterion for selecting the DOAC dose and investigate clinical characteristics of ischemic stroke (IS) under this criterion.
Source: Journal of the Neurological Sciences - January 25, 2022 Category: Neurology Authors: Takafumi Mashiko, Shigeru Fujimoto, Satoshi Suda, Arata Abe, Yasuyuki Iguchi, Yoshiki Yagita, Takao Kanzawa, Seiji Okubo, Todo Kenichi, Mineo Yamazaki, Nobuhito Nakajima, Kimito Kondo, Takeshi Inoue, Takeshi Iwanaga, Yuka Terasawa, Kensaku Shibazaki, Kazu Source Type: research

Echocardiographic predictors of cardioembolic stroke due to underlying atrial fibrillation: Reliable left atrial remodeling signs in acute stroke
Atrial remodeling due to high-burden atrial fibrillation (AF) is associated with cardioembolic stroke (CES). As not all CESs is caused by AF, we analyzed the diagnostic values of each echocardiographic parameter to distinguish likely AF-related CES in acute stroke patients while in non-AF rhythm.
Source: Journal of the Neurological Sciences - May 31, 2021 Category: Neurology Authors: Keiko Shimamoto, Hideaki Kanzaki, Tomotaka Tanaka, Atsushi Hirayama, Masatoshi Koga, Kengo F. Kusano, Kazunori Toyoda, Satoshi Yasuda, Masafumi Ihara Source Type: research

Stroke risk associated with carotid and aortic atherosclerosis in patients with atrial fibrillation: A systematic review
This review aimed to summarize the evidence on the risk of thromboembolism associated with carotid and aortic atherosclerosis in patients with AF, and the potential impact of their inclusion in current stroke risk stratification scores.
Source: Journal of the Neurological Sciences - April 10, 2021 Category: Neurology Authors: Jean Jacques Noubiap, Joseph Kamtchum-Tatuene, John L. Fitzgerald, Prashanthan Sanders Tags: Review Article Source Type: research

Adherence to anticoagulant guideline for atrial fibrillation: A large care gap among stroke patients in a rural population
This study aimed to investigate the prevalence and factors associated with oral anticoagulant undertreatment of atrial fibrillation (AF) among a cohort of rural patients with stroke outcomes and examine how undertreatment may influence a patient's one-year survival after stroke.
Source: Journal of the Neurological Sciences - March 20, 2021 Category: Neurology Authors: Johan Diaz, Eric Koza, Durgesh Chaudhary, Shima Shahjouei, Md Mobasshir Arshed Naved, Muhammad Taimur Malik, Jiang Li, Mohammad Adibuzzaman, Paul Griffin, Vida Abedi, Ramin Zand Source Type: research

Influence of atrial fibrillation detection time on outcome after endovascular thrombectomy
Cardiac emboli secondary to atrial fibrillation (AF) commonly cause large vessel occlusions (LVO) that require endovascular thrombectomy (EVT) to restore cerebral circulation. Whether the outcome of patients with AF diagnosed after the index stroke (newAF) differs from that of AF-patients in which AF was known before stroke (kAF) remains unknown.
Source: Journal of the Neurological Sciences - October 14, 2020 Category: Neurology Authors: R.R. Leker, A. Farraj, A. Filioglo, T. Sacagiu, A. Honig, J.M. Gomori, J.E. Cohen Source Type: research

Diagnostic value of N-terminal pro B-type natriuretic peptide for nonvalvular atrial fibrillation in acute ischemic stroke patients: A retrospective multicenter case-control study
The objective of this study is to evaluate the N-terminal pro B-type natriuretic peptide (NT-proBNP) diagnostic value for NVAF and the clinical outcome of AIS patients.
Source: Journal of the Neurological Sciences - April 5, 2020 Category: Neurology Authors: Jingjing Zhao, Yi Zhang, Fang Yuan, Changgeng Song, Yongli Jiang, Qiong Gao, Xiuxiu Leng, Wen Jiang Source Type: research

Cilostazol uncovers covert atrial fibrillation in non-cardioembolic stroke
We hypothesized that administration of cilostazol may clarify the occult atrial fibrillation (AF) during hospitalization in mild stroke patients, who has no history of AF.
Source: Journal of the Neurological Sciences - March 20, 2020 Category: Neurology Authors: Junya Aoki, Yasuyuki Iguchi, Takao Urabe, Hiroshi Yamagami, Kenichi Todo, Shigeru Fujimoto, Koji Idomari, Nobuyuki Kaneko, Takeshi Iwanaga, Tadashi Terasaki, Ryota Tanaka, Nobuaki Yamamoto, Akira Tsujino, Koichi Nomura, Koji Abe, Masaaki Uno, Yasushi Okad Source Type: research

Timing to start anticoagulants after acute ischemic stroke with non-valvular atrial fibrillation
To identify timing for initiation of anticoagulation therapy in acute ischemic stroke (AIS) with non-valvular AF as regards safety and efficacy by detecting the rate of intracranial haemorrhage (ICH) and recurrent ischemic symptoms (RIS) during follow-up.
Source: Journal of the Neurological Sciences - November 21, 2019 Category: Neurology Authors: Aishah Ibrahim Al Bakr, Reem Saeed AlOmar, Mona A.F. Nada, Noman Ishaque, Danah Aljaafari, Kawthar Hadiah, Fahd Ali Al Khmais, Azra Sohail Zafar, Rizwana Shahid, Erum Mobasir Shariff, Alaa Al Majid, Hanan Habib Khalid, Majid Alabdli Source Type: research

Large vessel occlusion stroke due to dislodged aortic valve calcification revealed by imaging and histopathology
The search for aetiology in ischemic stroke represents one of the most challenging, costly and critical issues to set up adequate secondary prevention strategies. However, despite extensive clinical examinations, up to one-third of ischemic strokes have no established cause (cryptogenic stroke) [1]. In patients with two or more potential risk factors for stroke, final aetiology often cannot be properly defined. Moreover, even when a major risk factor is present, e.g., atrial fibrillation or atherosclerotic vessel stenosis, stroke aetiology often remains presumptive.
Source: Journal of the Neurological Sciences - November 6, 2019 Category: Neurology Authors: A. Genchi, G. Schwarz, A. Semerano, M. Callea, F. Sanvito, F. Simionato, P. Panni, F. Scomazzoni, C. Doglioni, G. Comi, A. Falini, F. Ancona, M. Filippi, L. Roveri, M. Bacigaluppi Tags: Letter to the Editor Source Type: research

Effect of direct oral anticoagulant for acute major cerebral artery occlusion in cardioembolic stroke/transient ischemic attack patients with non-valvular atrial fibrillation
Direct oral anticoagulants (DOACs) can reduce the frequency of cardioembolic stroke with non-valvular atrial fibrillation as well as or better compared to vitamin K antagonists (VKAs). However, whether taking DOACs prior to stroke can prevent acute major cerebral artery occlusion (MCAO) has not been fully elucidated.
Source: Journal of the Neurological Sciences - May 22, 2019 Category: Neurology Authors: Shinya Tomari, Junnosuke Arima, Takashi Yoshida, Hitomi Yamashita, Reiko Sata, Rikuzo Hamada, Naoaki Kanda, Hiroshi Takashima Source Type: research

Atrial fibrillation, not atrial cardiopathy, is associated with stroke: A single center retrospective study
Atrial fibrillation (AF) increases the risk of thromboembolism. Atrial cardiopathy, defined as structural left atrial enlargement (LAE), has been proposed to be a unifying risk factor for stroke, with or without atrial fibrillation (AF). We sought to understand the relative importance of LAE and AF as risk factors for stroke.
Source: Journal of the Neurological Sciences - May 14, 2019 Category: Neurology Authors: Muhammad Affan, Abhimanyu Mahajan, Sumul Modi, Lonni Schultz, Angelos Katramados, Stephan A. Mayer, Daniel Miller Source Type: research

Accurate etiology diagnosis in patients with stroke and atrial fibrillation: A role for brain natriuretic peptide
Atrial fibrillation (AF) is the leading cause of cardioembolic stroke (CES), and patients with stroke and AF are frequently assumed to have CES. However, strokes presumably due to atherosclerotic pathophysiologies in large or small vessels can also occur in patients with AF. The aims of the present study were to clarify the prevalence of and factors related to a non-cardioembolic etiology in acute stroke patients with AF.
Source: Journal of the Neurological Sciences - March 28, 2019 Category: Neurology Authors: Yuki Sakamoto, Chikako Nito, Yasuhiro Nishiyama, Satoshi Suda, Noriko Matsumoto, Junya Aoki, Takashi Shimoyama, Takuya Kanamaru, Kentaro Suzuki, Yuki Go, Masahiro Mishina, Kazumi Kimura Source Type: research

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